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Mac Shine @macshine.bsky.social · 5d

Thanks Deb!

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Mac Shine @macshine.bsky.social · 12d

update - i found a copy. thanks all for boosting!

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Mac Shine @macshine.bsky.social · 12d

random neuroimaging question: does anyone in bluesky-land have access to the loadings for neurosynth topics in schaefer 400 (yeo7) space? #neuroskyence @misicbata.bsky.social @richardfbetzel.bsky.social @borismontreal.bsky.social @sofievalk.bsky.social

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Tim Viney @vineytj.bsky.social · 23d

*New preprint from the lab* – “Granularity of thalamic head direction cells”
doi.org/10.1101/2025...
🧠📈 🧪
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Granularity of thalamic head direction cells

Head direction signaling is fundamental for spatial orientation and navigation. The anterodorsal nucleus of the thalamus (ADn) contains a high density of head direction (HD) cells that process sensori...

doi.org

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Mac Shine @macshine.bsky.social · 26d

There's lots of opportunities in the brain for closures of these kinds, though I fear that this ultimately raises another set of even-more challenging questions: namely, how do our brains decipher between different circuit closures if they differ in their constraints? Fun to think about...

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Mac Shine @macshine.bsky.social · 26d

The short answer is yes, but we were quite limited in writing that paper to keep the text short and the references mostly to the last few years. I'm certainly not an expert on circular causality/constraint closure, but I do very much like the implications of the ideas

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Paul Middlebrooks @braininspired.bsky.social · 28d

What changes and what stays the same as you scale from single neurons up to local populations of neurons up to whole brains?

Michael and Mac @macshine.bsky.social on the systems approach to study brains across scales.

braininspired.co/podcast/220/

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Mehrdad Kashefi @mkashefi.bsky.social · Sep 6

Excited to share my latest work with @jonathanamichaels.bsky.social @diedrichsenjorn.bsky.social & @andpru.bsky.social!
We asked: How does the motor cortex account for arm posture when generating movement?
Paper 👉 www.biorxiv.org/content/10.1...
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Compositional neural dynamics during reaching

The complex mechanics of the arm make the neural control of reaching inherently posture dependent. Because previous reaching studies confound reach direction with final posture, it remains unknown how...

www.biorxiv.org

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Claire O'Callaghan @claireocallaghan.bsky.social · Aug 29

Adaptive learning is coordinated across behaviour, time and neurobiology (from synapses and dendrites, to astrocytes and the systems level).

If you’ve ever wondered how noradrenaline helps shape these multiscale learning processes, you might like this: www.cell.com/trends/cogni...

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Mac Shine @macshine.bsky.social · Aug 28

great episode! covered lots of cool territory -- great to see the concept of affordances coming back into the spotlight

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Paul Middlebrooks @braininspired.bsky.social · Aug 27

BI 219 Xaq Pitkow: Principles and Constraints of Cognition

YouTube video by Brain Inspired

www.youtube.com

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Nature Reviews Neuroscience @natrevneuro.nature.com · Aug 21

Theoretical neuroscience has room to grow — a Comment article by Ann Kennedy

@antihebbiann.bsky.social

#neuroscience #neuroskyence

www.nature.com/articles/s41...

Theoretical neuroscience has room to grow - Nature Reviews Neuroscience

The goal of theoretical neuroscience is to uncover principles of neural computation through careful design and interpretation of mathematical models. Here, I examine the use of top-down conceptual and...

www.nature.com

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Mac Shine @macshine.bsky.social · Aug 20

Massive congratulations Annie! Thoroughly well-deserved!!

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Mac Shine @macshine.bsky.social · Aug 18

Should have guessed that you would know the precise quote ;)

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Mac Shine @macshine.bsky.social · Aug 18

Haha yep. The son of the lobotomist... news.berkeley.edu/2016/04/27/n...

Neurophysiologist and philosopher Walter Freeman dies at 89 - Berkeley News

Pioneering neuroscientist focused on how the brain generates our perception of the world

news.berkeley.edu

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Mac Shine @macshine.bsky.social · Aug 18

thanks mate! much appreciated

a cartoon of a man with braces on his teeth says i think we have a winner

ALT: a cartoon of a man with braces on his teeth says i think we have a winner

media.tenor.com

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Mac Shine @macshine.bsky.social · Aug 18

@dryohanjohn.bsky.social @drbreaky.bsky.social @christopherjwhyte.bsky.social

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Mac Shine @macshine.bsky.social · Aug 18

I need some help from the #neuroskyence Bluesky-verse. Anyone know the source of this ~quote from Walter J. Freeman Jr.: "the secrets of the brain are hidden by two of God’s own firewalls: neurobiology and non-linear dynamics". I read it yrs ago but can't seem to find my way back to the source.

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Guido Meijer @guidomeijer.com · Aug 5

🚨Pre-print alert🚨

We stimulated serotonin with optogenetics while doing large-scale Neuropixel recordings across the mouse brain. We found strong widespread modulation of neural activity, but no effect on the choices of the mouse 🐭

How is this possible? Strap in! (1/9) 👇🧵

doi.org/10.1101/2025...

Serotonin drives choice-independent reconfiguration of distributed neural activity

Serotonin (5-HT) is a central neuromodulator which is implicated in, amongst other functions, cognitive flexibility. 5-HT is released from the dorsal raphe nucleus (DRN) throughout nearly the entire f...

doi.org

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Christopher Webb @cwebbonline.com · Jul 30

🚨 California and Hawaii under tsunami watch after 8.7M quake in Eastern Russia.

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Takuo Matsuzawa @matsuzawa.bsky.social · Jul 30

Tsunami Warning – 7/30, 9:40am
The Tsunami Advisory has been upgraded to a Tsunami Warning. Waves of up to 3m are expected. Those near coastal areas, rivers, or lakes should evacuate to higher ground immediately. #tsunami

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Robert Sansom @fossilrob.bsky.social · Jul 27

The point is, the monkeys making the loudest noise have the smallest balls.
pubmed.ncbi.nlm.nih.gov/26592343/

Evolutionary trade-off between vocal tract and testes dimensions in howler monkeys - PubMed

Males often face a trade-off between investments in precopulatory and postcopulatory traits [1], particularly when male-male contest competition determines access to mates [2]. To date, studies of pre...

pubmed.ncbi.nlm.nih.gov

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Claire Willett @clairewillett.bsky.social · Jul 22

Dem leadership should appoint an official Alt Press Secretary to give briefings after every one that Karoline Leavett does and just break them down lie by lie

maybe THAT’S the job we give Colbert 😂

Kevin M. Kruse @kevinmkruse.bsky.social · Jul 22

At this point, you should be embarrassed if your outlet has done nothing over these tumultuous six months to get itself barred by the administration.

The Wall Street Journal is speaking truth to power, but you're still on good terms with these assholes? Yeah, be proud of that.

Ned Resnikoff @resnikoff.bsky.social · Jul 21

Really difficult to make the argument that any reporter still in the White House pool isn't at best a scab and at worst a propagandist. www.politico.com/news/2025/07...

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The Transmitter @thetransmitter.bsky.social · Jul 18

An exciting collaboration is underway. @thetransmitter.bsky.social is partnering with @neuromatch.bsky.social to serve the computational neuroscience community and help connect neuroscientists across all career stages.
www.thetransmitter.org/neuromatch-p...

#neuroskyence

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shauna @goldengateblond.bsky.social · Jul 17

“the kindest person in the room is often the smartest.” JB Pritzker is a mensch.

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