Mariah Hoye
@mariahhoye.bsky.social
1.4K followers 510 following 97 posts
Scientific Project Manager in the NINDS Office of Research Quality Loves high-quality research, particularly in neuroscience and RNA biology Working to change the culture of science Views are my own
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Reposted by Mariah Hoye
jasonwilliamsny.bsky.social
Please share with anyone who cares about NSF support for graduate students and take 30 seconds to sign and leave a comment.

The deadline for the 2025 Graduate Research Fellowship Program is about one month away and literally no one can apply. #NSFGRFP

jasonjwilliamsny.github.io/grfp2025/
An Open Letter to U.S. STEM Leadership on the NSF Graduate Research Fellowship Program
An Open Letter to U.S. STEM Leadership on the NSF Graduate Research Fellowship Program
jasonjwilliamsny.github.io
Reposted by Mariah Hoye
mariahhoye.bsky.social
IMO, tackling our bias against null studies is essential for improving the culture of science.

We want high-quality science,

BUT we evaluate research and researchers more on the outcome of their work (“positive” findings, novelty, etc.) than the process by which those results were obtained.
plosbiology.org
Sharing knowledge is a fundamental principle within the scientific community, yet null and negative results are still being underreported. @scurry.bsky.social &co present a roadmap to a solution that has a role for everyone in the scientific community 🧪 #Academicsky #reproducibility
plos.io/3VwaU2O
Ending publication bias: A values-based approach to surface null and negative results
Sharing knowledge is a fundamental principle within the scientific community, yet null and negative results are still being underreported. This Consensus View discusses the problem of such publication...
plos.io
Reposted by Mariah Hoye
varechavala.bsky.social
No publicar todos los resultados de investigación, incluidos los "negativos" es un problema que tenemos que afrontar juntos... @scurry.bsky.social explica mucho mejor que yo lo que contamos en nuestro último paper. @plosbiology.org
scurry.bsky.social
Let's get negative about scholarly publishing – a new paper (first in a long time for me!) on proposals to tackle the problem of publication bias that emerged from a NINDS workshop held in May last year.
occamstypewriter.org/scurry/2025/... [Direct link to paper: journals.plos.org/plosbiology/...
Let’s get negative about scholarly publishing | Reciprocal Space
occamstypewriter.org
Reposted by Mariah Hoye
marymunson4.bsky.social
Grateful to @stephencurryuk.bsky.social and the other participants in this terrific workshop focused on how to combat our bias against publishing negative data (so important!) 👇
scurry.bsky.social
Let's get negative about scholarly publishing – a new paper (first in a long time for me!) on proposals to tackle the problem of publication bias that emerged from a NINDS workshop held in May last year.
occamstypewriter.org/scurry/2025/... [Direct link to paper: journals.plos.org/plosbiology/...
Let’s get negative about scholarly publishing | Reciprocal Space
occamstypewriter.org
Reposted by Mariah Hoye
Reposted by Mariah Hoye
plosbiology.org
Sharing knowledge is a fundamental principle within the scientific community, yet null and negative results are still being underreported. @scurry.bsky.social &co present a roadmap to a solution that has a role for everyone in the scientific community 🧪 #Academicsky #reproducibility
plos.io/3VwaU2O
Ending publication bias: A values-based approach to surface null and negative results
Sharing knowledge is a fundamental principle within the scientific community, yet null and negative results are still being underreported. This Consensus View discusses the problem of such publication...
plos.io
Reposted by Mariah Hoye
scurry.bsky.social
Let's get negative about scholarly publishing – a new paper (first in a long time for me!) on proposals to tackle the problem of publication bias that emerged from a NINDS workshop held in May last year.
occamstypewriter.org/scurry/2025/... [Direct link to paper: journals.plos.org/plosbiology/...
Let’s get negative about scholarly publishing | Reciprocal Space
occamstypewriter.org
Reposted by Mariah Hoye
jeremymberg.bsky.social
There are currently 11 acting Institute and Center directors at NIH and this will add another. Two more and the majority of these positions will be vacant.
jeremymberg.bsky.social
Hearing from multiple sources that Jon Lorsch is stepping down as NIGMS Director to become Deputy Director for Extramural Research, a job he has held in an acting capacity for some time.
mariahhoye.bsky.social
This is an awesome primer for peer review and also a helpful guide to get people thinking about the quality of their own experimental design!

Kudos to the authors!
mariahhoye.bsky.social
Congrats @federicamosti.bsky.social and @debbysilver.bsky.social lab! I’m excited to read it!!
debbysilver.bsky.social
Sharing our newest study led by the incredibly talented @federicamosti.bsky.social investigating new molecular mechanisms of human brain development. We discover a human-specific enhancer HAR1984 that influences chromatin looping to promote cortical size and folding! www.biorxiv.org/cgi/content/...
Reposted by Mariah Hoye
needhibhalla.bsky.social
I am honored to be selected as an ASCB fellow! SO much thanks to those who nominated me and provided letters of support!

And congratulations to the other Fellows selected! 🎉🥳🎊
Reposted by Mariah Hoye
davidimiller.bsky.social
🧪 Senate appropriators say: NIH's budget gets a... boost!

Rather than 40% cut, NIH gets a $400M *increase* in the Senate committee bill for FY26 (about +1%).

"Congress has your back," said @murray.senate.gov.

ADVOCACY MATTERS! There's still a long road (esp in the House), so keep up pressure.
Full Committee Markup of Defense and Labor, Health and Human Services, and Education Appropriations Acts | United States Senate Committee on Appropriations
United States Senate Committee on Appropriations
www.appropriations.senate.gov
Reposted by Mariah Hoye
mhagenauer.bsky.social
🧠 Tomorrow (6/24: 12-1) I will be doing an interactive webinar with Christophe Bernard and Daniela Schiller to discuss our paper, “Promoting Open Discussions of Scientific Failure within the Annual Society for Neuroscience Conference”. Come join & submit questions!
neuronline.sfn.org/scientific-r...
Promoting Open Discussions of Scientific Failure within the Annual Society for Neuroscience Conference
<p>Join this interactive session as Megan Hagenauer and Daniela Schiller discuss their paper, &ldquo;<a href="https://doi.org/10.1523/ENEURO.0524-24.2024">Promoting Open Discussions of Scientific Fail...
neuronline.sfn.org
Reposted by Mariah Hoye
flscitriguy.bsky.social
Also be sure to read the instructions a Forms I SF424. These Fs will have the new format/review instructions so there are different components from the previous NOFOs.
flscitriguy.bsky.social
Yas! Parent F32 (PA-25-423) and F30s (PA-25-426, PA-25-425) are also published.
simpler.grants.gov
mariahhoye.bsky.social
And I would take issue if a study with null outcomes was written up to say “this proves the null hypothesis”, etc, but rigorously-conducted null studies are important contributions to a body of scientific evidence.

I really like how this paper lays it out: elifesciences.org/articles/21451
Reposted by Mariah Hoye
thenewstats.bsky.social
What happens when scientists discuss mistakes they've made?

Here's a lovely paper about developing of a conference series normalizing errors ("Oh Sh*t: Great Scientists Tell Stories About Their Greatest Failures").

#stats #neuroscience #metascience #neuroskyence

tinyurl.com/5n96e5em
Promoting Open Discussions of Scientific Failure within the Annual Society for Neuroscience Conference
The annual Society for Neuroscience (SfN) meeting is a bonanza of scientific achievement: famous keynote speakers, beautiful scientific results, and award ceremonies. This focus is exciting and invigo...
doi.org
mariahhoye.bsky.social
I love this paper too!

The author, Rick Born, is part of the @comm4rigor.bsky.social which is developing educational units on topics like confirmation bias!

For anyone interested in learning more, check out the beta form of the unit at c4r.io (and give us feedback so we can keep improving it)!
mariahhoye.bsky.social
Also no 😅

But I take your point. I think the issue in my field (molecular/cellular neuroscience) and many others is that numerous studies have shown that we apply more scrutiny to studies with null outcomes than positive ones, even when you condition on experimental design (sample size, etc).
Reposted by Mariah Hoye
dralexharris.bsky.social
What does a 40% NIH budget cut mean for funding chances (now ~15%)?

You might think “60% of the money left = 9% success”

❌ NOPE!!!

1-3%

because 80% of the budget is for existing grants

New science? Starved
Ongoing grants? Slashed 😢

#FundingScienceSavesLives
Reposted by Mariah Hoye
tyk314.net
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