Mark Hirsch
@markahirsch.bsky.social
Movement scientist @Carolinas Rehabilitation Adjunct Professor @Wakeforestmed studying #exercise #plasticity #Parkinson disease #neurotrophins #collaboration
Reposted by Mark Hirsch
The more active you are, the easier it is to manage your Parkinson's symptoms.
But some symptoms - like rigidity, anxiety and risk of falls - can make exercise daunting.
👉 Read our top tips on how to exercise safely with Parkinson's: buff.ly/5BHF8QB
#Parkinsons #Parkinson
But some symptoms - like rigidity, anxiety and risk of falls - can make exercise daunting.
👉 Read our top tips on how to exercise safely with Parkinson's: buff.ly/5BHF8QB
#Parkinsons #Parkinson
July 16, 2025 at 10:02 AM
The more active you are, the easier it is to manage your Parkinson's symptoms.
But some symptoms - like rigidity, anxiety and risk of falls - can make exercise daunting.
👉 Read our top tips on how to exercise safely with Parkinson's: buff.ly/5BHF8QB
#Parkinsons #Parkinson
But some symptoms - like rigidity, anxiety and risk of falls - can make exercise daunting.
👉 Read our top tips on how to exercise safely with Parkinson's: buff.ly/5BHF8QB
#Parkinsons #Parkinson
Reposted by Mark Hirsch
🚨 NEW: we're proud to launch our new Parkinson's Passport!
Planning a holiday? ✈️ The Parkinson's Passport gives you a handy record of your important medical info, making travel with #Parkinsons less stressful.
👉 Download in French, English, Italian or German: buff.ly/8IbHN0Z
#Parkinson
Planning a holiday? ✈️ The Parkinson's Passport gives you a handy record of your important medical info, making travel with #Parkinsons less stressful.
👉 Download in French, English, Italian or German: buff.ly/8IbHN0Z
#Parkinson
May 12, 2025 at 10:01 AM
🚨 NEW: we're proud to launch our new Parkinson's Passport!
Planning a holiday? ✈️ The Parkinson's Passport gives you a handy record of your important medical info, making travel with #Parkinsons less stressful.
👉 Download in French, English, Italian or German: buff.ly/8IbHN0Z
#Parkinson
Planning a holiday? ✈️ The Parkinson's Passport gives you a handy record of your important medical info, making travel with #Parkinsons less stressful.
👉 Download in French, English, Italian or German: buff.ly/8IbHN0Z
#Parkinson
Reposted by Mark Hirsch
A new important lens on demoralization in Parkinson’s disease. Do you have a plan if you encounter demoralization? Spoiler alert: Demoralization affects about 1 in 5 w/ Parkinson's. This is a must-read article. Demoralization is tragically under-recognized. #parkinson @parkinsondotorg.bsky.social
July 3, 2025 at 12:41 PM
A new important lens on demoralization in Parkinson’s disease. Do you have a plan if you encounter demoralization? Spoiler alert: Demoralization affects about 1 in 5 w/ Parkinson's. This is a must-read article. Demoralization is tragically under-recognized. #parkinson @parkinsondotorg.bsky.social
Reposted by Mark Hirsch
Is it time to tame the brain’s fire? Neuroinflammation is emerging across Parkinson's, Alzheimer's, neurodegeneration and beyond. An important new Science article from Shi and colleagues pulls back the curtain on neuroinflammation. Could be a silent driver of destruction in Parkinson’s and beyond?
June 20, 2025 at 5:14 PM
Is it time to tame the brain’s fire? Neuroinflammation is emerging across Parkinson's, Alzheimer's, neurodegeneration and beyond. An important new Science article from Shi and colleagues pulls back the curtain on neuroinflammation. Could be a silent driver of destruction in Parkinson’s and beyond?
Reposted by Mark Hirsch
We have the guidelines, so why aren’t we referring to PT and other therapies for Parkinson’s? Let me say this clearly: There are strong evidence-based guidance to refer people w/ Parkinson’s to physical therapy early and regularly. Yet, it’s not happening. Why? #parkinson #physicaltherapy
June 21, 2025 at 1:57 PM
We have the guidelines, so why aren’t we referring to PT and other therapies for Parkinson’s? Let me say this clearly: There are strong evidence-based guidance to refer people w/ Parkinson’s to physical therapy early and regularly. Yet, it’s not happening. Why? #parkinson #physicaltherapy
Reposted by Mark Hirsch
Constipation in Parkinson's is a huge unmet challenge. We must unclog the pipeline. Great article in HealthCentral this week shining light on this topic by Cheyenne Buckingham. She interviewed a few of us in the field and summarized approaches to treatment. #parkinson #constipation
June 26, 2025 at 12:13 PM
Constipation in Parkinson's is a huge unmet challenge. We must unclog the pipeline. Great article in HealthCentral this week shining light on this topic by Cheyenne Buckingham. She interviewed a few of us in the field and summarized approaches to treatment. #parkinson #constipation
Reposted by Mark Hirsch
Disabled people should be involved from the outset in developing digital tools and services that are fundamental to work, life and play to maximise the transformative benefits they can bring says our new report on #DisabilityTechnology, released today.
June 23, 2025 at 8:06 AM
Disabled people should be involved from the outset in developing digital tools and services that are fundamental to work, life and play to maximise the transformative benefits they can bring says our new report on #DisabilityTechnology, released today.
Reposted by Mark Hirsch
The most complex disease in medicine is Parkinson's? YES.
- Multiple organ systems.
- Not a single disease.
- A single biomarker or diagnostic test exists: no
- Disease course is highly variable.
- Complicated regimens.
- Lot's of different symptoms, dopamine awakening, DBS and beyond.
- Multiple organ systems.
- Not a single disease.
- A single biomarker or diagnostic test exists: no
- Disease course is highly variable.
- Complicated regimens.
- Lot's of different symptoms, dopamine awakening, DBS and beyond.
April 30, 2025 at 2:21 PM
The most complex disease in medicine is Parkinson's? YES.
- Multiple organ systems.
- Not a single disease.
- A single biomarker or diagnostic test exists: no
- Disease course is highly variable.
- Complicated regimens.
- Lot's of different symptoms, dopamine awakening, DBS and beyond.
- Multiple organ systems.
- Not a single disease.
- A single biomarker or diagnostic test exists: no
- Disease course is highly variable.
- Complicated regimens.
- Lot's of different symptoms, dopamine awakening, DBS and beyond.
#WorldParkinsonDay!
Collaboration is key. Let's take a moment to reaffirm that we will double our efforts for a cure to #Parkinsons in this moment!
Collaboration is key. Let's take a moment to reaffirm that we will double our efforts for a cure to #Parkinsons in this moment!
April 11, 2025 at 6:34 PM
#WorldParkinsonDay!
Collaboration is key. Let's take a moment to reaffirm that we will double our efforts for a cure to #Parkinsons in this moment!
Collaboration is key. Let's take a moment to reaffirm that we will double our efforts for a cure to #Parkinsons in this moment!
Reposted by Mark Hirsch
Check out the amazing Bas Bloem discussing: Citius, Fortius, Altius—Understanding Which Components Drive Exercise Benefits in Parkinson Disease https://ja.ma/3H4JzMG via @JAMANeuro part of @JAMANetwork @basbloem @DrISubramanian
Citius, Fortius, Altius—Understanding Which Components Dr...
The expression “citius, fortius, altius” (Latin for “fast...
ja.ma
December 1, 2024 at 11:42 PM
Check out the amazing Bas Bloem discussing: Citius, Fortius, Altius—Understanding Which Components Drive Exercise Benefits in Parkinson Disease https://ja.ma/3H4JzMG via @JAMANeuro part of @JAMANetwork @basbloem @DrISubramanian
Reposted by Mark Hirsch
Today is #InternationalWomensDay ❤️
We're proud to mark the day with @salsbergmathews.bsky.social, who has released new illustrations of the Five Stages of Parkinson's (which typically depict older white men) featuring a diverse range of women.
Find out more: buff.ly/VPYHHFw
#IWD2025 #Parkinsons
We're proud to mark the day with @salsbergmathews.bsky.social, who has released new illustrations of the Five Stages of Parkinson's (which typically depict older white men) featuring a diverse range of women.
Find out more: buff.ly/VPYHHFw
#IWD2025 #Parkinsons
March 8, 2025 at 9:19 AM
Today is #InternationalWomensDay ❤️
We're proud to mark the day with @salsbergmathews.bsky.social, who has released new illustrations of the Five Stages of Parkinson's (which typically depict older white men) featuring a diverse range of women.
Find out more: buff.ly/VPYHHFw
#IWD2025 #Parkinsons
We're proud to mark the day with @salsbergmathews.bsky.social, who has released new illustrations of the Five Stages of Parkinson's (which typically depict older white men) featuring a diverse range of women.
Find out more: buff.ly/VPYHHFw
#IWD2025 #Parkinsons
Reposted by Mark Hirsch
Parkinson's, in my opinion, is the most complex disease in clinical medicine. Though it is nice to see these evidence-based reviews, we should keep our eye on the 'ball.' The ball is dynamic, and in Parkinson's will fluctuate over time, and especially with disease progression. Listen to the person.
March 8, 2025 at 2:51 PM
Parkinson's, in my opinion, is the most complex disease in clinical medicine. Though it is nice to see these evidence-based reviews, we should keep our eye on the 'ball.' The ball is dynamic, and in Parkinson's will fluctuate over time, and especially with disease progression. Listen to the person.
Reposted by Mark Hirsch
📋 If you've taken part in clinical trials, you'll probably have completed questionnaires (or PROMS - Patient-Reported Outcome Measures) about how you perceive your trial experience.
Our Strategic Director Amelia has co-authored a paper about how to improve this process: https://buff.ly/41hdMTG
Our Strategic Director Amelia has co-authored a paper about how to improve this process: https://buff.ly/41hdMTG
February 25, 2025 at 11:14 AM
📋 If you've taken part in clinical trials, you'll probably have completed questionnaires (or PROMS - Patient-Reported Outcome Measures) about how you perceive your trial experience.
Our Strategic Director Amelia has co-authored a paper about how to improve this process: https://buff.ly/41hdMTG
Our Strategic Director Amelia has co-authored a paper about how to improve this process: https://buff.ly/41hdMTG
Reposted by Mark Hirsch
In case you need this today 💙
February 25, 2025 at 1:10 PM
In case you need this today 💙
Reposted by Mark Hirsch
The idea that manipulating peripheral nerve afferents as a treatment for tremor is not crazy, however it needed to be tested. For this device, a highly controlled study revealed to us that vibrotactile stimulation failed to improve tremor.
February 25, 2025 at 1:56 PM
The idea that manipulating peripheral nerve afferents as a treatment for tremor is not crazy, however it needed to be tested. For this device, a highly controlled study revealed to us that vibrotactile stimulation failed to improve tremor.
Reposted by Mark Hirsch
We’re thrilled to hear from Dr. Andreas Horn, this year’s Brain Stimulation Early Career Award winner, at #BrainStimConf today! Congratulations on this well-deserved recognition @andreashorn.org #BrainStim2025 @braistimjournal.bsky.social @braincircuits.bsky.social
February 25, 2025 at 5:20 AM
We’re thrilled to hear from Dr. Andreas Horn, this year’s Brain Stimulation Early Career Award winner, at #BrainStimConf today! Congratulations on this well-deserved recognition @andreashorn.org #BrainStim2025 @braistimjournal.bsky.social @braincircuits.bsky.social
Reposted by Mark Hirsch
I've been living in a hot spot for 20 years
Where you live could be important for breathing particulate matter and later coming down with Parkinson's?
Mississippi-Ohio River Valley? State-of-the-art geographic analytic techniques showed association between PM2.5 and PD that varied in strength by region.
n.neurology.org/content/earl...
Mississippi-Ohio River Valley? State-of-the-art geographic analytic techniques showed association between PM2.5 and PD that varied in strength by region.
n.neurology.org/content/earl...
November 16, 2024 at 2:21 PM
I've been living in a hot spot for 20 years
Reposted by Mark Hirsch
Should you get a continuous glucose monitoring device to prevent dementia in diabetes, Parkinson's, Alzheimer's and beyond? There is rising evidence. Historia vero testis temporum – history is the the witness of the ages – and it is thus time for researchers to put this to to the test.
February 6, 2025 at 11:56 AM
Should you get a continuous glucose monitoring device to prevent dementia in diabetes, Parkinson's, Alzheimer's and beyond? There is rising evidence. Historia vero testis temporum – history is the the witness of the ages – and it is thus time for researchers to put this to to the test.
I've been living in a hot spot for 20 years
Where you live could be important for breathing particulate matter and later coming down with Parkinson's?
Mississippi-Ohio River Valley? State-of-the-art geographic analytic techniques showed association between PM2.5 and PD that varied in strength by region.
n.neurology.org/content/earl...
Mississippi-Ohio River Valley? State-of-the-art geographic analytic techniques showed association between PM2.5 and PD that varied in strength by region.
n.neurology.org/content/earl...
November 16, 2024 at 2:21 PM
I've been living in a hot spot for 20 years
Reposted by Mark Hirsch
Parkinson's disease progresses however levodopa does not stop working. There are long-term benefits. Levodopa response over time was documented in this study. Response to levodopa did not weaken after a 4-year follow-up in 63 fluctuators. Axial symptoms worsen. prd-journal.com/article/S135...
October 3, 2023 at 4:24 PM
Parkinson's disease progresses however levodopa does not stop working. There are long-term benefits. Levodopa response over time was documented in this study. Response to levodopa did not weaken after a 4-year follow-up in 63 fluctuators. Axial symptoms worsen. prd-journal.com/article/S135...
Reposted by Mark Hirsch
Do you know the forgotten drugs that block dopamine receptors and worsen Parkinson's?
Amisulpride (Barhemsys)
Metoclopramide (Reglan, Gimoti)
Droperidol (Inapsine)
Chlorpromazine (Thorazine)
Prochlorperazine (Compazine, Compro).
pubs.acs.org/doi/10.1021/...
Amisulpride (Barhemsys)
Metoclopramide (Reglan, Gimoti)
Droperidol (Inapsine)
Chlorpromazine (Thorazine)
Prochlorperazine (Compazine, Compro).
pubs.acs.org/doi/10.1021/...
October 12, 2023 at 12:03 PM
Do you know the forgotten drugs that block dopamine receptors and worsen Parkinson's?
Amisulpride (Barhemsys)
Metoclopramide (Reglan, Gimoti)
Droperidol (Inapsine)
Chlorpromazine (Thorazine)
Prochlorperazine (Compazine, Compro).
pubs.acs.org/doi/10.1021/...
Amisulpride (Barhemsys)
Metoclopramide (Reglan, Gimoti)
Droperidol (Inapsine)
Chlorpromazine (Thorazine)
Prochlorperazine (Compazine, Compro).
pubs.acs.org/doi/10.1021/...
Tango Argentino and experience of shame in #Parkinson’s
"In general, participants described reduced body fatigue, anxiety, shame and frustration and increase in joy, pride, curiosity as well as reinforcement of partnership"
pubmed.ncbi.nlm.nih.gov/31987239/
"In general, participants described reduced body fatigue, anxiety, shame and frustration and increase in joy, pride, curiosity as well as reinforcement of partnership"
pubmed.ncbi.nlm.nih.gov/31987239/
November 16, 2024 at 2:07 PM
Tango Argentino and experience of shame in #Parkinson’s
"In general, participants described reduced body fatigue, anxiety, shame and frustration and increase in joy, pride, curiosity as well as reinforcement of partnership"
pubmed.ncbi.nlm.nih.gov/31987239/
"In general, participants described reduced body fatigue, anxiety, shame and frustration and increase in joy, pride, curiosity as well as reinforcement of partnership"
pubmed.ncbi.nlm.nih.gov/31987239/
Reposted by Mark Hirsch
Do you know how many people hide their diagnosis of Parkinson's disease? HALF (50%). Can you believe it?
Read this month's blog: everything you need to know about stigma and Parkinson's by Indu Subramanian with assist from Brad McDaniels and Soania Mathur.
www.parkinsonsecrets.com/blog/what-yo...
Read this month's blog: everything you need to know about stigma and Parkinson's by Indu Subramanian with assist from Brad McDaniels and Soania Mathur.
www.parkinsonsecrets.com/blog/what-yo...
October 12, 2023 at 5:55 PM
Do you know how many people hide their diagnosis of Parkinson's disease? HALF (50%). Can you believe it?
Read this month's blog: everything you need to know about stigma and Parkinson's by Indu Subramanian with assist from Brad McDaniels and Soania Mathur.
www.parkinsonsecrets.com/blog/what-yo...
Read this month's blog: everything you need to know about stigma and Parkinson's by Indu Subramanian with assist from Brad McDaniels and Soania Mathur.
www.parkinsonsecrets.com/blog/what-yo...