Mark Bitter
@markcbitter.bsky.social
230 followers 270 following 61 posts
Postdoc at Stanford University. Interested in pop. gen., adaptation, and a wholesome scientific community. he/him
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markcbitter.bsky.social
Thrilled to see this work, led by @lisacouper.bsky.social now out!
We quantified variation in thermal tolerance in the mosquito, Aedes sierrensis, to quantify how adaptation may alter disease vector distributions under warming. 🧵
www.pnas.org/doi/10.1073/...
www.pnas.org
Reposted by Mark Bitter
jpverta.bsky.social
One week to apply for our fully funded PhD position in Norway! This is a really exciting project in collab. with University of Helsinki and Benchmark Genetics.

Samples are ready - you do (read: learn) everything - functional genomics, bioinformatics, genotype-phenotype associations 🤩

Please RT!
jpverta.bsky.social
How do regulatory genes control alternative life histories? We have an open PhD position to answer this question using functional genomics in Atlantic salmon.

Apply by October 15th through www.jobbnorge.no/en/available...

Please share widely! 🧬🦑🖥️
Reposted by Mark Bitter
jmkreiner.bsky.social
Human-mediated land-use and climate change occur simultaneously, but how do they interact to shape adaptive dynamics? Super excited to share the first paper from the Kreiner lab, led by postdoc extraordinaire @rpineau.bsky.social
Reposted by Mark Bitter
snbogan.bsky.social
New preprint led by undergrad Owen Moosman! We uncover extensive haplotype diversity in antifreeze protein gene copy number in polar Zoarcoidei fishes, and report new tools to evaluate assembly uncertainty and switch error in phased genomes www.biorxiv.org/content/10.1...
Reposted by Mark Bitter
petrovadmitri.bsky.social
Very excited to see this work in press! I think there is a reason to believe that this is a common means of stabilizing large-effect polymorphisms in general and might be an important reason for why diploidy is so common. news.stanford.edu/stories/2025...
Reposted by Mark Bitter
skylerberardi.bsky.social
Check out our paper in Evolution Letters!

We used D. melanogaster pigmentation as a focal trait to explore parallelism in phenotypic and genomic responses to environmental change - read more at the link below 👇
evolletters.bsky.social
How predictably does complex trait adaptation proceed over space and time in wild populations?
doi.org/10.1093/evle...

Now in @evolletters.bsky.social by @skylerberardi.bsky.social, @paulrschmidt.bsky.social et al.

📷: Dr. Rush Dhillon
Figure showing the experimental overview as a graphic. Remaining alt text taken from the figure caption in the paper: (A) we sampled flies from six wild orchard populations ranging from Homestead, FL, to Lancaster, MA, and established isofemale lines in the laboratory. (B) We returned to a focal orchard in Media, PA, at early- and late-season timepoints and collected flies to capture evolutionary patterns following winter and summer conditions. (C) We then seeded outdoor mesocosms (N = 9) with an outbred population originating from early-season collections in Media, PA, and sampled flies at the end of summer (mid-season) and fall (late-season) to determine if seasonal patterns are recapitulated in experimental populations controlled for migration, drift, and cryptic population structure. (D) Across each wild or experimental context, we sampled flies, established lines in the lab, completed common garden treatment to remove environmental effects, and scored females for abdominal pigmentation. We also conducted pooled DNA sequencing on additional flies sampled from each population to map genomic patterns for candidate pigmentation SNPs.
Reposted by Mark Bitter
nanditagarud.bsky.social
I am seeking a postdoc for my group at UCLA. We work at the intersection of population genetics x microbiome (garud.eeb.ucla.edu). If interested, please message me!
Garud Lab
garud.eeb.ucla.edu
Reposted by Mark Bitter
klohmueller.bsky.social
Come join us at UCLA!!! We have a growing population genetics community here and Nandita and her lab are outstanding!
nanditagarud.bsky.social
I am seeking a postdoc for my group at UCLA. We work at the intersection of population genetics x microbiome (garud.eeb.ucla.edu). If interested, please message me!
Garud Lab
garud.eeb.ucla.edu
Reposted by Mark Bitter
ksxue.bsky.social
The Xue lab at UC Irvine is looking for a staff scientist to support our work investigating how microbes interact and evolve in the gut microbiome! Open to a wide range of previous experience levels, see ad for more.
recruit.ap.uci.edu/JPF09601
Junior, Assistant, or Associate Specialist – Xue Lab
University of California, Irvine is hiring. Apply now!
recruit.ap.uci.edu
Reposted by Mark Bitter
petrovadmitri.bsky.social
We are recruiting students who are thinking of applying to Biology PhD programs this fall to apply for the Stanford Biology Preview Program. Please spread the word!
stanfordbpp.bsky.social
Applying to Biology PhD programs this year? Let us help!

At BPP, we aim to support students from all backgrounds through the grad school application process. Learn more about grad student life and receive 1-on-1 feedback on your application materials!

Apply here: forms.gle/EvTyUWXFMRSL...
Reposted by Mark Bitter
1/n 🧵 Excited to share our new paper! We developed a framework to reveal hidden simplicity in how organisms adapt to different environments, particularly focusing on antibiotic resistance evolution. #EvolutionaryBiology #MachineLearning
biorxiv-evobio.bsky.social
Learning the Shape of Evolutionary Landscapes: Geometric Deep Learning Reveals Hidden Structure in Phenotype-to-Fitness Maps https://www.biorxiv.org/content/10.1101/2025.05.07.652616v1
Reposted by Mark Bitter
Reposted by Mark Bitter
contaminatedsci.bsky.social
Our commentary on the elegant in vitro microbiome coalescence experiments from @goldmandoran.bsky.social @ksxue.bsky.social et al is out.

It was a pleasure to write about one of my favorite microbiome papers of the last few years.

www.pnas.org/doi/10.1073/...
Mixing microbiomes in vitro reveals rules of community assembly | PNAS
Mixing microbiomes in vitro reveals rules of community assembly
www.pnas.org
Reposted by Mark Bitter
maikemorrison.bsky.social
1/ Hey y'all, I'm excited to share my latest paper, which is out now in PNAS! We introduce FAVA, a statistical framework to measure compositional variability across microbiome samples. If you want to measure variability across a stacked bar plot, FAVA is for you! Paper: doi.org/10.1073/pnas...
5 relative abundance plots arranged to have increasing compositional variability (variability across relative abundance samples, here vertical bars)
Reposted by Mark Bitter
lisacouper.bsky.social
Thank you for the coverage! Excited that this work, in collaboration with @markcbitter.bsky.social and many others, is now out!
Reposted by Mark Bitter
berkeleypublichlth.bsky.social
A new study led by #EnvironmentalHealth postdoc Lisa Couper finds #mosquitoes may genetically adapt to #ClimateChange more than expected. Her team's findings show increasing risk of #WestNileVirus, #Malaria & other diseases due to the insects' heat tolerance. #GlobalWarming ow.ly/Uzro50V3BRl
New research shows mosquitoes may be able to adapt to warming temperatures
The heat tolerance the research team saw “exceeds that of projected climate warming,” according to the published paper.
ow.ly
Reposted by Mark Bitter
wormsrock.bsky.social
Late-stage PhD students:

We want to bring you to NYU Biology to meet peers and make connections with potential postdoctoral mentors. Apply to be part of our Emerging Scholars Symposium!
Emerging Scholars Symposium 2025
as.nyu.edu
Reposted by Mark Bitter
harmitmalik.bsky.social
If you have been affected by the fires in LA, or are concerned about your ability to keep precious Drosophila strains going during the latest funding crisis, we will host your strains as a backup. Please email me.

Please amplify. If you are also able to host fly strains, add your name as well.
Reposted by Mark Bitter
evobioclio.bsky.social
Join us at the Gordon Research Seminar (GRS) on Ecological and Evolutionary Genomics in Tuscany, co-chaired by @jcbnunez.bsky.social and me.
If you’d like to present your research and be considered for a talk, make sure to submit your application before April 6th!
2025 Ecological and Evolutionary Genomics (GRS) Seminar GRC
The 2025 Gordon Research Seminar on Ecological and Evolutionary Genomics (GRS) will be held in Lucca (Barga), Lucca Italy. Apply today to reserve your spot.
www.grc.org
Reposted by Mark Bitter
seungsookim.bsky.social
Hello Bluesky friends! I am a #newPI starting at UC Irvine in April, interested in gene regulation and functional genomics in stem cell models of development (esp neural crest). We are hiring at all levels – please reach out/spread the word! sskimlab.org
Kim Lab at UC Irvine
Visit the post for more.
sskimlab.org
Reposted by Mark Bitter
mkarag.bsky.social
How is functional variation at large-effect loci maintained in natural populations?

Thrilled to share our work showing how beneficial dominance reversal helps fruit flies maintain a resistance polymorphism as selection varies in their environment! A thread 🧵 1/n

www.biorxiv.org/content/10.1...
Dominance reversal maintains large-effect resistance polymorphism in temporally varying environments
A central challenge in evolutionary biology is to uncover mechanisms maintaining functional genetic variation1. Theory suggests that dominance reversal, whereby alleles subject to fluctuating selectio...
www.biorxiv.org
Reposted by Mark Bitter
markcbitter.bsky.social
Thrilled to see this work, led by @lisacouper.bsky.social now out!
We quantified variation in thermal tolerance in the mosquito, Aedes sierrensis, to quantify how adaptation may alter disease vector distributions under warming. 🧵
www.pnas.org/doi/10.1073/...
www.pnas.org
markcbitter.bsky.social
In sum, quantifying the adaptive potential of mosquito populations to global warming is critical to accurately forecast changes to disease vector distributions under warming. Stay tuned for exciting extensions of this work!
markcbitter.bsky.social
Finally, we used the parameters quantified from experiment in an evolutionary rescue model and found that our focal population has the potential to track warming as projected under moderate emissions scenarios.