Mark Oblivious 🧬🧫🔬
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markhill.bsky.social
Mark Oblivious 🧬🧫🔬
@markhill.bsky.social
Mass spectrometrist helping deliver safer and more effective biopharmaceuticals
Nothing says American Society For Mass Spectrometry (ASMS) more than 7am breakfast vendor seminars!

#science #massspec #chemistry #biopharmaceutical #ASMS2025
June 3, 2025 at 7:13 PM
Antibody Drug Conjugates American Society For Mass Spectrometry (ASMS) 😆😆 ⚗️🧪👨‍🔬👩‍🔬🔬

#ASMS2025 #Chemistry #pharma #ADC #massspec
June 3, 2025 at 6:37 PM
🔬 ** 𝐀𝐝𝐯𝐚𝐧𝐜𝐞𝐦𝐞𝐧𝐭𝐬 𝐢𝐧 𝐀𝐥𝐳𝐡𝐞𝐢𝐦𝐞𝐫’𝐬 𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡: 𝐏𝐫𝐨𝐭𝐞𝐨𝐟𝐨𝐫𝐦 𝐋𝐚𝐧𝐝𝐬𝐜𝐚𝐩𝐞 𝐨𝐟 𝐓𝐚𝐮 𝐟𝐫𝐨𝐦 𝐭𝐡𝐞 𝐇𝐮𝐦𝐚𝐧 𝐁𝐫𝐚𝐢𝐧 ** 🧠

www.linkedin.com/posts/mark-h...
May 23, 2025 at 7:17 PM
Science Pope Joke from the other place...😀
May 8, 2025 at 8:17 PM
🌟🔬 **𝐔𝐧𝐥𝐨𝐜𝐤𝐢𝐧𝐠 𝐭𝐡𝐞 𝐌𝐲𝐬𝐭𝐞𝐫𝐢𝐞𝐬 𝐨𝐟 𝐁𝐢𝐨𝐦𝐨𝐥𝐞𝐜𝐮𝐥𝐞𝐬 𝐰𝐢𝐭𝐡 𝐗-𝐑𝐚𝐲 𝐌𝐚𝐬𝐬 𝐒𝐩𝐞𝐜𝐭𝐫𝐨𝐦𝐞𝐭𝐫𝐲 𝐓𝐞𝐜𝐡𝐧𝐨𝐥𝐨𝐠𝐲!** 🌟🔬🌟

King et al publication presents some very intresting and novel work on X-ray mass spectrometry technology for structural biology.

📌 Publication Link
lnkd.in/eeWv4ive
May 8, 2025 at 9:18 AM
🔎 Leblanc et al recent study unveils the complexities of the IgG2 antibody subclass, which is known for its unique disulfide bond connectivity within its hinge region, giving rise to three isoforms: A, A/B, and B.

pubs.acs.org/doi/10.1021/...
April 27, 2025 at 3:04 PM
"You gotta do this one for me, Billy. McGarnagle.....train the processor.."
April 7, 2025 at 6:39 AM
On this Day in chemistry, Roger Tsien was born.

He shares the 2008 Nobel Prize in Chemistry with Osamu Shimomura and Martin Chalfie for their discovery of the green fluorescent protein (GFP).
February 1, 2025 at 12:22 PM
On this day in science Karl von Frisch was born

He shared the 1973 Nobel Prize for Physiology or Medicine. He showed that bees have the ability to recognize different odours and tastes, and discovered their famous "waggle dance" used by bees to communicate among with others in the hive.
November 20, 2024 at 2:24 PM
On this day American scientist George Wald was born

Wald was an American biochemist who shared the 1967 Nobel Prize for Physiology or Medicine for “for their discoveries concerning the primary physiological and chemical visual processes in the eye.”
November 18, 2024 at 1:27 PM
On this day in science Humphry Davy announced the elementary nature of chlorine (Cl).

It was previously thought that chlorine was a compound rather than an element, named oxymuriatic acid.

Compound Interest Chemistry infographics
November 15, 2024 at 8:37 AM
On this day in science biochemist Edward A. Doisy was born

He shared the Nobel Prize in Physiology or Medicine in 1943 for the isolation and synthesis of vitamin K, which encourages blood clotting and has several applications in medicine.
November 13, 2024 at 1:06 PM
On this day in science Antoine Lavoisier declared water to be a compound, not an element in 1783.

The French nobleman performed an experiment using hydrogen (H) and oxygen (O). The product of a reaction between these elements was found to be water, which proved its composition
November 12, 2024 at 1:23 PM
On this day in science Jack Szostak was born. He received the 2009  Nobel Prize (medicine) for his work on Telomeres

Telomeres are structures made from DNA sequences and proteins found at the ends of chromosomes. They cap and protect the end of a chromosome like the end of a shoelace.
November 9, 2024 at 11:21 AM
Today is National Pumpkin 🎃 Day (US) .

Pumpkins are a member of the gourd family, which includes cucumbers, honeydew melons, cantaloupe, watermelons and zucchini. Most people don’t realize they are fruits — not vegetables. L.”

But what is the chemistry ⚗️ of Pumpkins 🎃
October 26, 2024 at 10:28 AM
On this day in science Andrew Fire was born

Who received the 2006 Nobel Prize in Medicine for his work on RNA interference - gene silencing by double-stranded RNA.

RNAi is short for “RNA interference” and it refers to a phenomenon where small pieces of RNA can shut down protein translation
April 27, 2024 at 9:07 AM
Contaminant Spot Check and Removal Assay (ContamSPOT) for Mass Spectrometry Analysis

Here, Smeriglio et al describes a novel method to check for and remove small contamination for peptide maping and proteomic analysis.
www.biorxiv.org/content/10.1...
January 9, 2024 at 1:16 PM
Some really nice work by Pagel et al. demonstrating the power of Ion mobility for O-glycan analysis compared to classical LCMS methodologies , see image

www.researchsquare.com/article/rs-3...
January 5, 2024 at 10:56 AM
Happy Christmas 🎄 everyone one
December 25, 2023 at 2:53 PM
Happy Winter Solstice 😀
 
On the December Solstice, the Northern Hemisphere is at the farthest away from the sun. It’s why the days become shorter, and the nights become longer during this time. December Solstice marks the official beginning of winter.
December 21, 2023 at 10:43 AM
Chemistry advent No 4. What is the chemistry mistletoe

The plant’s romantic overtones most likely started with the Celtic Druids of the 1st century A.D. Because mistletoe could blossom even during the frozen winter
@compoundchem.bsky.social
December 4, 2023 at 9:29 AM
Chemistry advent No 3. What is the chemistry of mulled wine.

The Victorians seem to have popularised mulled wine in the UK. Charles Dickens writes of a spiced wine called “Smoking Bishop” and later Mrs Beeton describes using spices to “mull wine”.
@compoundchem.bsky.social
December 3, 2023 at 6:14 PM
Chemistry advent No 2. What is the chemistry poinsettia

Poinsettia plants are native to Central America, especially an area of southern Mexico known as 'Taxco del Alarcon' where they flower during the winter

Poinsettias are great plants to indicate the pH of a liquid.
December 2, 2023 at 4:43 PM
On this day in science the discovery of iodine (I) was announced in 1813

Iodine was first discovered by Barnard Courtois, while extracting potassium and sodium from seaweed ash. When he accidentally added sulfuric acid, a violet colored cloud evolved from the mass.
@compoundchem.bsky.social
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November 29, 2023 at 8:04 AM
Today in National Book Week (US). But what is the chemistry of the aroma of old and new books @compoundchem.bsky.social
November 20, 2023 at 4:05 PM