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Reposted by Mashaal Sohail

Federico Sánchez Quinto @fsanchezquinto.bsky.social · Aug 29

Lo logramos! @paleogenomics.bsky.social @vvillaislas.bsky.social @mashaals.bsky.social @jcchacond.bsky.social #EduardoArrieta #AngelesTavares #MiriamBravo, #AleCastillo #MarceSandoval, Muchas gracias por su gran entusiasmo, dedicación y entrega. (Ayúdenme a taggear a quienes hacen falta).

Federico Sánchez Quinto @fsanchezquinto.bsky.social · Aug 29

La historia de cómo secuenciamos los mamtus 🦣 más tropicales 🏝️ secuenciados al momento la pueden leer aquí 👇https://shorturl.at/KE6Ux. Redactadó por el gran @rpocisv.bsky.social. Muchas gracias Rodrigo por cubrir con tanto entusiasmo la nota sobre nuestro trabajo.

Mammoths in Mexico? Huge bone trove reveals giant beasts thrived in warmth, too

Fossils found while building airport contain first mammoth DNA from tropical location

shorturl.at

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Reposted by Mashaal Sohail

Andrea Ganna @andganna.bsky.social · Jul 30

Leena Peltonen School of Human Genetics in full-swing!

@gosiatrynka.bsky.social
@dgmacarthur.bsky.social
@bpasaniuc.bsky.social
@tuuliel.bsky.social
@hilarycmartin.bsky.social
@sashagusevposts.bsky.social
@zkutalik.bsky.social
@mashaals.bsky.social
@alemedinarivera.bsky.social

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Mashaal Sohail @mashaals.bsky.social · Jul 11

@biointeractive.bsky.social ambassadors are from the US, Canada, Mexico and Puerto Rico, and are doing the important work of developing, workshopping and studying teaching materials that will shape the minds of the youth.

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Mashaal Sohail @mashaals.bsky.social · Jul 11

Absolutely wonderful experience helping train HHMI bioambassadors to teach high school and college biology in non-deterministic frameworks and with a deep understanding of the multi-scale complexity of human genetic variation @biointeractive.bsky.social @hhmijanelia.bsky.social

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Mashaal Sohail @mashaals.bsky.social · Jun 24

Mi charla como parte del serie de charlas públicas sobre Genética humana y Paleogenómica

Genes entrelazados, historias compartidas
Intertwined genes, shared histories

www.youtube.com/watch?v=Naen...

Genes entrelazados, historias compartidas

YouTube video by elcolegionacionalmx

www.youtube.com

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Mashaal Sohail @mashaals.bsky.social · Jun 24

Full cycle of talks on Human Genetics and Paleogenomics is available on YouTube with El Colegio Nacional MX Fundación UNAM (some in English and some in Spanish) @sarahtishkoff.bsky.social @jnovembre.bsky.social @fsanchezquinto.bsky.social @gcbias.bsky.social and others!

youtube.com/playlist?lis...

Genómica Humana Y Paleogenómica // Human Genetics and Paleogenomics - YouTube

Since our origins we have wondered where we come from. The research on genomics, paleogenomics and the human genome are now providing answers on this questio...

youtube.com

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Reposted by Mashaal Sohail

Diego Ortega-Del Vecchyo @delvecchyo.bsky.social · Jun 10

Happy to have worked on this project with @mashaals.bsky.social , Emilia Huerta-Sanchez and Valeria Añorve-Garibay. We analyzed how stabilizing and directional selection cause problems to predict traits in ancient samples.

Mashaal Sohail @mashaals.bsky.social · Jun 10

Our new work is now out in AJHG "Natural selection acting on complex traits hampers the predictive accuracy of polygenic scores in ancient samples." Great collaboration with @delvecchyo.bsky.social and Emilia Huerta-Sanchez, led by Valeria Añorve-Garibay.

The American Journal of Human Genetics @ajhgnews.bsky.social · Jun 10

📣Online now!
📄Natural selection acting on complex traits hampers the predictive accuracy of polygenic scores in ancient samples
🧑‍🤝‍🧑 @delvecchyo.bsky.social @mashaals.bsky.social & co

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Mashaal Sohail @mashaals.bsky.social · Jun 10

Thanks, it was fixed, and shortly the whole talk will be available there on YT. It was also streaming on facebook.
www.facebook.com/fundacion.un...

¿Qué pistas nos puede dar la genética sobre la historia evolutiva humana? | 🪨 🌎 "¿Qué pistas nos puede dar la genética sobre la historia evolutiva humana? Perspectivas de estudios globales".🧬🤔 👉 Coor...

🪨 🌎 "¿Qué pistas nos puede dar la genética sobre la historia evolutiva humana? Perspectivas de estudios globales".🧬🤔 👉 Coordinan: Lic. Dionisio A....

www.facebook.com

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Mashaal Sohail @mashaals.bsky.social · Jun 10

Our new work is now out in AJHG "Natural selection acting on complex traits hampers the predictive accuracy of polygenic scores in ancient samples." Great collaboration with @delvecchyo.bsky.social and Emilia Huerta-Sanchez, led by Valeria Añorve-Garibay.

The American Journal of Human Genetics @ajhgnews.bsky.social · Jun 10

📣Online now!
📄Natural selection acting on complex traits hampers the predictive accuracy of polygenic scores in ancient samples
🧑‍🤝‍🧑 @delvecchyo.bsky.social @mashaals.bsky.social & co

Natural selection acting on complex traits hampers the predictive accuracy of polygenic scores in ancient samples

Using polygenic scores, we find that two types of natural selection, stabilizing selection and directional selection, can decrease the prediction accuracy of complex traits in ancient individuals. We ...

www.cell.com

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Mashaal Sohail @mashaals.bsky.social · Jun 5

www.science.org/content/arti...

Race, ethnicity don’t match genetic ancestry, according to a large U.S. study

Data from the All of Us program confirm what many geneticists have long promoted

www.science.org

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Mashaal Sohail @mashaals.bsky.social · Jun 5

Subcontinental genetic variation in the All of Us Research Program: Implications for biomedical research
www.cell.com/ajhg/fulltex...

Subcontinental genetic variation in the All of Us Research Program: Implications for biomedical research

Analysis of 230,016 genomes in the All of Us Research Program revealed substantial variation in continental and subcontinental ancestry within self-reported race and ethnicity across the US. Subcontin...

www.cell.com

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Reposted by Mashaal Sohail

Stefano Cacciatore @tkcaccia.bsky.social · Jun 2

KODAMA goes spatial.
doi.org/10.1101/2025...
#spatialtranscriptomics #visium #visiumhd #seurat #giotto

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Mashaal Sohail @mashaals.bsky.social · Apr 23

“Genes and geography: understanding human genetic variation” by @jnovembre.bsky.social, second talk in this cycle of talks on Human genomics and Paleogenomics for a general audience.
Tuesday 29th November 12pm Mexico City time/1pm central time/2pm est.

colnal.mx/agenda/genes...

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Mashaal Sohail @mashaals.bsky.social · Apr 21

African evolutionary genomics: reconstructing human evolution and the genetic basic of complex adaptive traits by @sarahtishkoff.bsky.social, Tuesday 22nd April 12pm Mexico City time.

colnal.mx/agenda/afric...

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Mashaal Sohail @mashaals.bsky.social · Apr 3

Honored to be mentioned for my contributions in human evolutionary genetics!

www.nature.com/articles/s41...

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Mashaal Sohail @mashaals.bsky.social · Apr 2

Register for the UPennn symposium on “Inclusive Genomics to Promote Health Excellence” organized by @sarahtishkoff.bsky.social and @bpasaniuc.bsky.social at the Center for Global Genomics & Health Equity and the Center for Computational Biomedicine.
Link: upenn.co1.qualtrics.com/jfe/form/SV_...

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Reposted by Mashaal Sohail

The American Journal of Human Genetics @ajhgnews.bsky.social · Mar 26

📣New from Yang et al.
📄Fine-mapping in admixed populations using CARMA-X, with applications to Latin American studies
www.cell.com/ajhg/abstrac...

Fine-mapping in admixed populations using CARMA-X, with applications to Latin American studies

CARMA-X is a robust fine-mapping method for admixed populations, leveraging ancestry-specific data to identify putative causal variants. By modeling cross-ancestry correlations and accounting for LD v...

www.cell.com

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Mashaal Sohail @mashaals.bsky.social · Mar 26

Nice collaboration with Luliana Lonita-Laza's group at Columbia. "Fine-mapping in admixed populations using CARMA-X, with applications to Latin American studies" now out in
@ajhgnews.bsky.social
@scientist-ninja.bsky.social
authors.elsevier.com/c/1kqIJgeXDypv
www.cell.com/ajhg/fulltex...

Fine-mapping in admixed populations using CARMA-X, with applications to Latin American studies

CARMA-X is a robust fine-mapping method for admixed populations, leveraging ancestry-specific data to identify putative causal variants. By modeling cross-ancestry correlations and accounting for LD v...

www.cell.com

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Mashaal Sohail @mashaals.bsky.social · Mar 25

When in evolutionary time does accelerated genomic change occur across phenotypes? Our study out in Cell Genomics led by Eucharist Kun, with Vagheesh Narasimhan integrates comparative, functional, and ancient genomic data with GWAS. Read more www.cell.com/cell-genomic...

The trait-specific timing of accelerated genomic change in the human lineage

Kun et al. examine the timing of accelerated genomic changes in human evolution by linking human traits to genomic annotations related to distinct evolutionary points. Their findings reveal that skele...

www.cell.com

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Mashaal Sohail @mashaals.bsky.social · Mar 25

New perspective "Evolution, genetic diversity and health" led by PhD student @madmaxolotl.bsky.social and post-doc @scientist-ninja.bsky.social in @naturemedicine.bsky.social
nature.com/articles/s41...
PDF here: rdcu.be/eczeW

Evolution, genetic diversity, and health - Nature Medicine

This Perspective explains how past migrations and environmental exposures have influenced genomic diversity, and how understanding and contextualizing this diversity is crucial to advancing precision ...

nature.com

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Reposted by Mashaal Sohail

El Agus de Komodo @elagusdekomodo.bsky.social · Feb 25

Hoy nos la pasamos muy bien en Mutante, con @mashaals.bsky.social

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Mashaal Sohail @mashaals.bsky.social · Jan 27

Tracing human trait evolution through integrative genomics and temporal annotations, a preview of our recent study with Eucharist Kun and Vagheesh Narasimhan
www.cell.com/cell-genomic...

Tracing human trait evolution through integrative genomics and temporal annotations

Understanding the evolution of human traits is a fundamental yet challenging question. In a recent Cell Genomics article, Kun et al. integrate large-scale genomic and phenotypic data, including deep-l...

www.cell.com

Mashaal Sohail @mashaals.bsky.social · Jan 22

🌟 Excited to teach at The Leena Peltonen School of Human Genetics in 2025!

This prestigious summer school brings together leaders in human genetics with PhD students

📅 July 27-31, 2025

📍 Wellcome Genome Campus, UK

📝 Apply by March 7 at www.lpshg.com

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Mashaal Sohail @mashaals.bsky.social · Dec 19

Excited to share our pre-print "The multi-scale complexity of human genetic variation beyond continental groups" biorxiv.org/cgi/content/...
Global Genomic Network Communities browser: sohail-lab.shinyapps.io/GG-NC/
Github: github.com/mariajpalma/...
See🧵by lead author @madmaxolotl.bsky.social

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