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Reposted by Matt Smear

eartha mae @endoeartha.bsky.social · 13d

Very excited and proud to share my postdoctoral research with @neurrriot.bsky.social looking at the context-specific encoding of social behavior 💃🕺 in hormone-sensitive, large-scale brain networks in mice!

www.biorxiv.org/content/10.1...

#neuroskyence #compneurosky 🧪
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pwashlab.bsky.social @pwashlab.bsky.social · 20d

A POSTDOCTORAL POSITION ON THE NEUROBIOLOGY OF REPRODUCTION IN A CHANGING ENVIRONMENT: We are recruiting a postdoctoral fellow to work on a Neurobiology in Changing Ecosystems (NiCE) award from NSF and the Kavli Foundation (www.kavlifoundation.org/news/kavli-a...).

Kavli and NSF Announce New Grant Awards to Advance Neurobiology in…

An initiative to explore how nervous systems function and evolve in dynamic natural environments

www.kavlifoundation.org

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Matt Smear @mattsmear.bsky.social · 27d

falling rent free in our head

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Rachel Bedford, PhD @rachelbedfordphd.bsky.social · 28d

The BioE department at the @uoknightcampus.bsky.social is hiring 2 complementary TTF neuroengineering positions!

We're looking for someone with expertise in experimental & translational neuroengineering and someone else with expertise in computational & data-science neuroengineering.

#neurosky

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Adrien Peyrache @apeyrache.bsky.social · Sep 8

Fluorescent proteins can now act as qubits 🤯
This opens the door for single cell MRI in vivo and highly localized sensors that map magnetic fields, temperature gradients, etc. Insane.

www.nature.com/articles/s41...

A fluorescent-protein spin qubit - Nature

An optically addressable fluorescent-protein spin qubit is realized using enhanced yellow fluorescent protein; the qubit can be coherently controlled at liquid-nitrogen temperatures and the spin detec...

www.nature.com

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Matt Smear @mattsmear.bsky.social · Sep 8

www.science.org/doi/abs/10.1...

Cooperative actions of interneuron families support the hippocampal spatial code

Identifying the computational roles of different neuron families is crucial for understanding neural networks. Most neural diversity is embodied in various types of γ-aminobutyric acid–mediated (GABAe...

www.science.org

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Dan Levenstein @dlevenstein.bsky.social · Sep 7

“If everything is everywhere, why have distinct areas? Here we show that the function of a brain area is more related to how different types of information are combined (formatted) in neural representations than merely whether that information is present.”

Marlene Cohen @marlenecohen.bsky.social · Jan 4

New results for a new year! “Linking neural population formatting to function” describes our modern take on an old question: how can we understand the contribution of a brain area to behavior?
www.biorxiv.org/content/10.1...
🧠👩🏻‍🔬🧪🧵
#neuroskyence
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Linking neural population formatting to function

Animals capable of complex behaviors tend to have more distinct brain areas than simpler organisms, and artificial networks that perform many tasks tend to self-organize into modules (1-3). This sugge...

www.biorxiv.org

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Matt Smear @mattsmear.bsky.social · Sep 4

Full text of
"The Organization Of Behavior:
A Neuropsychological Theory"

archive.org/stream/in.er...

archive.org

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Matt Smear @mattsmear.bsky.social · Sep 4

“Instead of a joker to occasionally confuse the student of behavior, nonsensory activities appear in every fall of the cards and must make up a large share of the deck. Neurophysiologically, it may even become a problem to account for any consistent effect of a specific stimulus."
Donald Hebb (1949)

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Ben Hayden @benhayden.bsky.social · Sep 4

Speaking with 20+ years of experience, I strongly believe that if these guys had done their experiment in primate instead of mouse, they would have gotten exactly the same results.

E.g.
www.cell.com/current-biol...

Choice-relevant information transformation along a ventrodorsal axis in the medial prefrontal cortex - Nature Communications

Choice-relevant computations across the medial prefrontal cortex differ only quantitatively between areas. Here the authors suggest these computations may be organized along a functional gradient.

www.nature.com

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Reposted by Matt Smear

Venki Murthy @neurovenki.bsky.social · Sep 1

We watched mice follow scent trails drawn on an “endless” treadmill. By manipulating trail geometry/statistics, perturbing mouse nose & brain, and modeling behavior with a Bayesian framework, we show that mice use predictive (rather than reactive) strategies.

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Matt Smear @mattsmear.bsky.social · Aug 20

We’re searching for a Developmental Neuroscientist! Building on UO’s rich tradition in the field, we’re excited to welcome the next scientist to carry it forward.

Adam C. Miller, University of Oregon @drzebrafish.bsky.social · Aug 14

The University of Oregon is searching for an Assistant Professor with a focus on Developmental Neuroscience. We are excited to have you come join us - apply!
Application information can be found at: careers.uoregon.edu/cw/en-us/job...

Current Opportunities | UO HR Website

careers.uoregon.edu

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Matt Smear @mattsmear.bsky.social · Aug 27

#internationaldogday

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Matt Smear @mattsmear.bsky.social · Aug 25

let’s hope that @greatdismal.bsky.social ‘s precognitions are less prescient than they used to be… www.penguinrandomhouse.com/series/TJ3/t...

The Jackpot Trilogy

Buy books online and find book series such as The Jackpot Trilogy written by William Gibson from PenguinRandomHouse.com

www.penguinrandomhouse.com

Reposted by Matt Smear

Isaac Bianco @isaacbianco.bsky.social · Aug 23

Latest from the lab. Beautiful work from Joanna Lau and a fantastic collaboration with James Fitzgerald.

www.cell.com/current-biol...

Supraspinal commands have a modular organization that is behavioral context specific

Lau et al. use calcium imaging and statistical modeling to comprehensively survey reticulospinal activity during diverse locomotor behaviors. They find that a small set of functional modules act combi...

www.cell.com

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Matt Smear @mattsmear.bsky.social · Aug 20

We’re searching for a Developmental Neuroscientist! Building on UO’s rich tradition in the field, we’re excited to welcome the next scientist to carry it forward.

Adam C. Miller, University of Oregon @drzebrafish.bsky.social · Aug 14

The University of Oregon is searching for an Assistant Professor with a focus on Developmental Neuroscience. We are excited to have you come join us - apply!
Application information can be found at: careers.uoregon.edu/cw/en-us/job...

Current Opportunities | UO HR Website

careers.uoregon.edu

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Reposted by Matt Smear

Joseph D. Zak @josephdzak.bsky.social · Aug 20

Proud to share Kai Clane Belonio’s latest work in our lab. Kai showed that induced-depression decreases behavioral tolerance of aversive odorants as well as increases in neuroinflammation in sensory affective areas. Also contributing are @nervenkidd.bsky.social and Eyerusalem Haile.

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · Aug 20

Neuroinflammation in Olfactory Circuits Underlies Odor Hypersensitivity in a Rodent Model of Depression https://www.biorxiv.org/content/10.1101/2025.08.14.670114v1

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Matt Smear @mattsmear.bsky.social · Aug 15

the psychophysicist’s “noise” is an experimental subject’s ________ ?

Marlene Cohen @marlenecohen.bsky.social · Aug 15

Ramanujan Srinath collected & analyzed many data sets including Amy Ni’s, Yunlong (Draco) Xu & Brent Doiron modeled, & Doug did a causal experiment. The key is: when noise and signal come from the same circuit (they must!), then smart, flexible decisions have a strong relationship with noise. 4/

Matt Smear @mattsmear.bsky.social · Aug 15

maybe “noise” isn’t the best word for it?

Marlene Cohen @marlenecohen.bsky.social · Aug 15

@ramanujan-s.bsky.social and a fantastic team of coauthors figured out a resolution: we propose that correlated variability isn’t noise that corrupts a signal or something to ignore. It reflects the activity in the population that is read out to guide behavior. 3/

Reposted by Matt Smear

Marlene Cohen @marlenecohen.bsky.social · Aug 15

Hmm: Correlated variability in sensory neurons (how much responses fluctuate together) is related to behavior: it’s modulated by attention, learning, & motivation and related to individual decisions. But because it's low-D, in theory its effect on behavior should be small. What’s up with that? 2/

a husky puppy is laying on the floor with its tongue out and wearing a blue collar .

ALT: a husky puppy is laying on the floor with its tongue out and wearing a blue collar .

media.tenor.com

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Reposted by Matt Smear

Marlene Cohen @marlenecohen.bsky.social · Aug 15

Ramanujan Srinath collected & analyzed many data sets including Amy Ni’s, Yunlong (Draco) Xu & Brent Doiron modeled, & Doug did a causal experiment. The key is: when noise and signal come from the same circuit (they must!), then smart, flexible decisions have a strong relationship with noise. 4/

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Matt Smear @mattsmear.bsky.social · Aug 3

Advertise your account with a GIF

Reposted by Matt Smear

Evan D Vickers @evandvickers1.bsky.social · May 29

I'm pleased to announce that the Version of Record of our eLife paper, "Pan-cortical 2-photon mesoscopic imaging and neurobehavioral alignment in awake, behaving mice" (Vickers and McCormick, 2024) is now available at: elifesciences.org/articles/94167 (94167.3, VOR).

Pan-cortical 2-photon mesoscopic imaging and neurobehavioral alignment in awake, behaving mice

Procedures were developed to perform mesoscale 2-photon Ca2+ imaging simultaneously from all of mouse dorsolateral neocortex, facilitating identification of widespread neural ensembles with activity r...

elifesciences.org

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Eduardo Schenberg, PhD @eeschenberg.bsky.social · Jul 21

Psychedelics are serotonergic drugs...

Right?!?

Well, think again and embrace the complexity revealed by @zenbrainest.bsky.social et al testing 41 compounds in 318 receptors: "psychedelics have potent and efficacious actions at nearly every serotonin, dopamine, and adrenergic receptor."

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Ann Kennedy @antihebbiann.bsky.social · Jul 15

Proposal recommended for funding! Which means we have a fresh, 3-year-funded position available for a computational postdoc interested in studying dynamics of social interactions in rats, with simultaneous Neuropixels data to follow 🐀🐀🐀

Proper job ad pending, but email me if interested!

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