Max Raas
@maxraas.bsky.social
PhD Candidate at Utrecht University & Hubrecht Institute | Evolutionary Cell Biology | Chromosome Segregation
Pinned
tinyurl.com
Our story on the kinetochore composition of the ciliate Tetrahymena thermophila is out now on bioRxiv! We find surprisingly many orthologs of conventional kinetochore components, but also components that have very different evolutionary origins. A 🧵 (1/11)
Check it out here: tinyurl.com/4ectm9x4
Check it out here: tinyurl.com/4ectm9x4
Our story on the kinetochore composition of the ciliate Tetrahymena thermophila is out now on bioRxiv! We find surprisingly many orthologs of conventional kinetochore components, but also components that have very different evolutionary origins. A 🧵 (1/11)
Check it out here: tinyurl.com/4ectm9x4
Check it out here: tinyurl.com/4ectm9x4
tinyurl.com
December 1, 2025 at 2:06 PM
Our story on the kinetochore composition of the ciliate Tetrahymena thermophila is out now on bioRxiv! We find surprisingly many orthologs of conventional kinetochore components, but also components that have very different evolutionary origins. A 🧵 (1/11)
Check it out here: tinyurl.com/4ectm9x4
Check it out here: tinyurl.com/4ectm9x4
Reposted by Max Raas
Happy to see our work published and glad to have contributed together with @maxraas.bsky.social ! Looking forward to all the projects that will come out of this work!
Excited to share our new paper in @cellreports.bsky.social that reshapes our understanding of chromosome organization's deep evolutionary roots! Our work dives into the origins of the machinery that structures our very genomes.
🔗: doi.org/10.1016/j.ce...
#Genomics #Evolution #CellBiology #LECA
🔗: doi.org/10.1016/j.ce...
#Genomics #Evolution #CellBiology #LECA
June 23, 2025 at 11:18 AM
Happy to see our work published and glad to have contributed together with @maxraas.bsky.social ! Looking forward to all the projects that will come out of this work!
Reposted by Max Raas
Excited to share our new paper in @cellreports.bsky.social that reshapes our understanding of chromosome organization's deep evolutionary roots! Our work dives into the origins of the machinery that structures our very genomes.
🔗: doi.org/10.1016/j.ce...
#Genomics #Evolution #CellBiology #LECA
🔗: doi.org/10.1016/j.ce...
#Genomics #Evolution #CellBiology #LECA
June 22, 2025 at 12:15 AM
Excited to share our new paper in @cellreports.bsky.social that reshapes our understanding of chromosome organization's deep evolutionary roots! Our work dives into the origins of the machinery that structures our very genomes.
🔗: doi.org/10.1016/j.ce...
#Genomics #Evolution #CellBiology #LECA
🔗: doi.org/10.1016/j.ce...
#Genomics #Evolution #CellBiology #LECA
Reposted by Max Raas
PRC1 and PRC2 proximal interactome in mouse embryonic stem cells
PRC1 and PRC2 proximal interactome in mouse embryonic stem cells
Zijlmans and Stelloo et al. profiled in vivo proximal interactomes of PRC1 and PRC2 in mouse embryonic stem cells, identifying >100 proteins, including transcription factors and RNA-binding proteins. Their findings reveal shared and distinct roles of…
dlvr.it
March 7, 2025 at 1:35 PM
PRC1 and PRC2 proximal interactome in mouse embryonic stem cells
Reposted by Max Raas
Ana Almeida, Helder Rocha, Maximilian Raas, Geert Kops, Reto Gassmann, Helder Maiato @i3suporto.bsky.social, et al. dissect the relationship between kinetochore size & CENP-E dependence for chromosome alignment.
journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
January 9, 2025 at 12:03 PM
Ana Almeida, Helder Rocha, Maximilian Raas, Geert Kops, Reto Gassmann, Helder Maiato @i3suporto.bsky.social, et al. dissect the relationship between kinetochore size & CENP-E dependence for chromosome alignment.
journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
Reposted by Max Raas
On the possibility of yet a third kinetochore system in the protist phylum Euglenozoa https://www.biorxiv.org/content/10.1101/2024.08.06.606595v1
On the possibility of yet a third kinetochore system in the protist phylum Euglenozoa https://www.biorxiv.org/content/10.1101/2024.08.06.606595v1
Transmission of genetic material from one generation to the next is a fundamental feature of all liv
www.biorxiv.org
August 7, 2024 at 4:30 PM
On the possibility of yet a third kinetochore system in the protist phylum Euglenozoa https://www.biorxiv.org/content/10.1101/2024.08.06.606595v1
Reposted by Max Raas
Online: our evolutionary interrogation of eukaryotic Structural Maintenance of Chromosomes (SMC) complexes @maxraas.bsky.social @eelcotromer.bsky.social @lauraeme.bsky.social #SMCcomplexes #eukaryogenesis #LECA #condensin #cohesin #evolutionarycellbiology #chromatin 🧵(1/6) doi.org/10.1101/2024...
Shaping up genomes: Prokaryotic roots and eukaryotic diversification of SMC complexes
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
doi.org
January 9, 2024 at 8:36 AM
Online: our evolutionary interrogation of eukaryotic Structural Maintenance of Chromosomes (SMC) complexes @maxraas.bsky.social @eelcotromer.bsky.social @lauraeme.bsky.social #SMCcomplexes #eukaryogenesis #LECA #condensin #cohesin #evolutionarycellbiology #chromatin 🧵(1/6) doi.org/10.1101/2024...
Reposted by Max Raas
My second paper of the year finally out!
While the Polycomb field is dominated by models based on a tight functional coupling between PRC1 and PRC2, we found compelling evolutionary support for the predominantly independent functions of PRC1 and PRC2.
www.nature.com/articles/s42...
While the Polycomb field is dominated by models based on a tight functional coupling between PRC1 and PRC2, we found compelling evolutionary support for the predominantly independent functions of PRC1 and PRC2.
www.nature.com/articles/s42...
Uncoupled evolution of the Polycomb system and deep origin of non-canonical PRC1 - Communications Bi...
A systematic characterization of the Polycomb system throughout the eukaryotic tree of life reveals that evolution of PRC1 and PRC2 has been largely uncoupled.
www.nature.com
November 10, 2023 at 1:52 PM
My second paper of the year finally out!
While the Polycomb field is dominated by models based on a tight functional coupling between PRC1 and PRC2, we found compelling evolutionary support for the predominantly independent functions of PRC1 and PRC2.
www.nature.com/articles/s42...
While the Polycomb field is dominated by models based on a tight functional coupling between PRC1 and PRC2, we found compelling evolutionary support for the predominantly independent functions of PRC1 and PRC2.
www.nature.com/articles/s42...