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mcb-sheffield.bsky.social @mcb-sheffield.bsky.social · 2d

We are delighted to host Harsha Kantamneni today from the University of Bradford.

"Endosomal Sorting Complex Required for Transport (ESCRT): Roles in receptor trafficking, signalling pathways, drug resistance and disease"

📍 Alfred Denny Conference Room

📅 18th October - 1pm

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Aga Gambus @agagambus.bsky.social · 3d

We are looking for a senior technician (can undertake PhD) at Uni of Birmingham (UK) to study chromatin replication and ubiquitylation using Xenopus egg extract. Deadline 28/10/25. Get in touch with me or @m-saponaro.bsky.social for informal inquiries. Please share.
www.jobs.ac.uk/job/DOW912/s...

Senior Research Technician at University of Birmingham

Explore an exciting academic career as a Senior Research Technician. Don't miss out on other academic jobs. Click to apply and explore more opportunities.

www.jobs.ac.uk

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Rainero lab @erainerolab.bsky.social · 10d

Congratulations to Shahd on passing her PhD viva!!!!
Thanks to Christoph and Jason @jasonkinglab.bsky.social for examining

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mcb-sheffield.bsky.social @mcb-sheffield.bsky.social · 22d

Amazing talk by Bella, from @helenkmatthews.bsky.social lab at #NECB2025

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mcb-sheffield.bsky.social @mcb-sheffield.bsky.social · 23d

More fascinating talks this morning by our final year students Megan Poxon (@jasonkinglab.bsky.social & @helenkmatthews.bsky.social), Nada Alosaimi (C. Smythe lab), Zhe Bao (@erainerolab.bsky.social), @rlawson954.bsky.social @helenkmatthews.bsky.social) and Ashleigh Whelan (Wilson lab)

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mcb-sheffield.bsky.social @mcb-sheffield.bsky.social · 24d

Great talks by our @mcb-sheffield.bsky.social speakers Grace Gilbert (@bose-lab.bsky.social & @tsakiridis.bsky.social), Francesca Brown (Humphreys lab) and Rob Hunton (@struttlab.bsky.social) at the 3rd year PGR symposium!! Back tomorrow morning - stay tuned!!

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Rainero lab @erainerolab.bsky.social · 25d

Here are our fantastic postdocs: Mona, Rachele & Eric
@mcb-sheffield.bsky.social
#NPAW2025
#PostdocAppreciationWeek

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Helen Matthews @helenkmatthews.bsky.social · Sep 9

Well done to our PhD student @rlawson954.bsky.social 👏

on giving a talk on her data on keratins and mitotic mechanics at the MBI-MPG conference at @mbisg.bsky.social in Singapore!

@mcb-sheffield.bsky.social

Mechanobiology Institute @mbisg.bsky.social · Sep 9

What happens to packed cells in a monolayer during mitosis? @rlawson954.bsky.social presented varying experiments investigating shape and force changes, cell-cell junctions, and mechanics in mitotic cells, suggesting important roles for keratin and desmosomes #MBIMPG2025 @helenkmatthews.bsky.social

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Matthew Freeman @mjafreeman.bsky.social · Sep 1

Are you a postdoc interested in the mechanisms of disease?

Do you have a great record and an exciting vision?

Come and start your own lab @dunnschool.bsky.social by applying for sponsorship for early career fellowships.

Deadline 30th September...pass it on!

www.path.ox.ac.uk/work-with-us...

Group Leader Career Development Fellowships - Dunn School

Are you an early career researcher interested in the cell or molecular mechanisms underlying disease? Do you have an outstanding record and an innovative research plan?

www.path.ox.ac.uk

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Victoria Hart @vichart33.bsky.social · Sep 1

Interested in Pancreatic Cancer Research? We are gearing up to host our 7th Sheffield Pancreatic Cancer Research Network meeting!

Check out the details at: sites.google.com/sheffield.ac...

@mcb-sheffield.bsky.social @fohsheffield.bsky.social

Sheffield Pancreatic Cancer Research Network - Events

Upcoming Events

sites.google.com

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Alex Gould Lab @alexgouldlab.bsky.social · Jul 1

Calling all meeting organizers… @biologists.bsky.social now have a calculator to estimate your event’s carbon footprint and to test various reduction scenarios.

thenode.biologists.com/event-carbon...

Event carbon calculator - the Node

I am excited to announce the release of our event carbon calculator, our latest resource to support the creation of sustainable events. Estimate your

thenode.biologists.com

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Derivery Lab - MRC LMB @deriverylab.bsky.social · Jun 23

🚨 JOB ALERT 🚨
We're hiring a Research Assistant – no PhD needed!
Join us to explore the molecular mechanisms of receptor sorting in endosomes.
Experience in protein expression/purification, cloning & cell culture desired 🧫🔬
Apply now 👉 www.nature.com/naturecareer...

#STEMCareers #ResearchJobs

A picture of 3 rows of people on steps at the MRC LMB. From left to right - top row: Akaash, Vic, Lara - Middle row: Kerrie, Manu, Paddy - bottom row: Meg and Julie

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Cassie Clarke @cassiejclarke.bsky.social · Jun 23

It was a pleasure to visit @sheffielduni.bsky.social
last week presenting our work "Neutrophil metabolism faciliates metastasis by influencing immune & ECM landscapes" at @mcb-sheffield.bsky.social seminar series.Thanks @erainerolab.bsky.social for the invitation & all who made it a memorable visit

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Victoria Hart @vichart33.bsky.social · Jun 23

I am excited to share our new Sheffield Pancreatic Cancer Research Network website! Please check it out at... sites.google.com/sheffield.ac... @fohsheffield.bsky.social @mcb-sheffield.bsky.social

Sheffield Pancreatic Cancer Research Network

Meet the Team

sites.google.com

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mcb-sheffield.bsky.social @mcb-sheffield.bsky.social · Jun 18

We are delighted to host @cassiejclarke.bsky.social
today from the @cruk-si.bsky.social!

"Neutrophil metabolism supports metastasis of mammary cancer by altering immune and extracellular matrix landscapes"

📍 Alfred Denny Conference Room
📅 10th June - 1pm

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mcb-sheffield.bsky.social @mcb-sheffield.bsky.social · Jun 12

📣 Postdoctoral position available!!!
Are you interested in translating molecular cell biology into potential cancer therapy?
This project will explore the role of EGFR trafficking in chemotherapy resistance in #breastcancer
🔬 Prof Liz Smythe lab
📅 Deadline: 3rd Jule
👇 www.jobs.ac.uk/job/DNJ622/r...

Research Associate (Cell Biology) at University of Sheffield

An opportunity for an academic position as a Research Associate (Cell Biology) is available, as advertised on jobs.ac.uk. Apply now and explore other academic job openings.

www.jobs.ac.uk

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Rainero lab @erainerolab.bsky.social · Jun 12

New addition to our lab's PhD Wall of Fame - Bian 🇸🇾
#WeAreInternational
@mcb-sheffield.bsky.social
@sheffielduni.bsky.social

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Dan Bose @danbose.bsky.social · Jun 6

Hot off the press for your Friday morning! 🔥 Our new (and highly revised!) preprint is out. It significantly expands on our previous work, unveiling exciting new data on how CBP's intrinsically disordered regions (IDRs) regulate genes.
Link to preprint: tinyurl.com/5npjkyps

#IDRs #condensates #CBP

CBP-IDRs regulate acetylation and gene expression.

Intrinsically disordered regions (IDRs) have emerged as crucial regulators of protein function, allowing proteins to sense and respond to their environment. Creb binding protein (CBP) and EP300 (p300)...

tinyurl.com

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mcb-sheffield.bsky.social @mcb-sheffield.bsky.social · Jun 6

Well done Bian!!

Rainero lab @erainerolab.bsky.social · Jun 5

Congratulations Bian on passing you PhD viva!!! Thanks to @zech-lab.bsky.social, @helenkmatthews.bsky.social and John for examining
@mcb-sheffield.bsky.social

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mcb-sheffield.bsky.social @mcb-sheffield.bsky.social · Jun 4

We are delighted to host @vickysanzmoreno.bsky.social today from the @icr.ac.uk!

"Biomechanical hallmarks and vulnerabilities of metastatic cancer cells"

📍 Alfred Denny Conference Room
📅 4th June - 1pm

@insigneoinstitute.bsky.social
@sheffielduni.bsky.social
@sheffielduni.bsky.social

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Rainero lab @erainerolab.bsky.social · May 22

Amazing talk by Ife at the @mcb-sheffield.bsky.social 2nd year PGR symposium

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Dan Bose @danbose.bsky.social · May 22

Bia doing a super job with her talk at the @mcb-sheffield.bsky.social 2nd year symposium!! 👏👏

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mcb-sheffield.bsky.social @mcb-sheffield.bsky.social · May 22

Second year PGR symposium with @drn-sheffield.bsky.social!
Exciting day full of science 🧬

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mcb-sheffield.bsky.social @mcb-sheffield.bsky.social · May 22

📣 New paper alert!

The El-khamisy lab uncovered how a key protein, NuMA, helps repair damaged DNA and protect important control regions of our genome, especially after oxidative stress.

🛡️ Protecting the genome = protecting health.
www.cell.com/cell-reports...

ADP-ribosylation of NuMA promotes DNA single-strand break repair and transcription

Abugable et al. investigated the role of ADP-ribosylation in NuMA function during DNA repair. They demonstrate that ADP-ribosylation-deficient NuMA impairs repair kinetics and transcription and fails ...

www.cell.com

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Dan Bose @danbose.bsky.social · May 12

Fantastic talk from @nicola-carruthers.bsky.social at today's @mcb-sheffield.bsky.social postdoc talk series! #CBP #RNAs #enhancers and everything in between- smashed it! 👏

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