Derivery Lab - MRC LMB
@deriverylab.bsky.social
Asymmetric cell division | Microscopy tech development | Synthetic biology | Fly models |
All views are our own
All views are our own
Reposted by Derivery Lab - MRC LMB
There’s just ONE WEEK left to apply to join our amazing PhD programme next year!
Visit our website for more information: www2.mrc-lmb.cam.ac.uk/students/int...
Applications close on 2nd DEC 2025
Visit our website for more information: www2.mrc-lmb.cam.ac.uk/students/int...
Applications close on 2nd DEC 2025
November 25, 2025 at 11:49 AM
There’s just ONE WEEK left to apply to join our amazing PhD programme next year!
Visit our website for more information: www2.mrc-lmb.cam.ac.uk/students/int...
Applications close on 2nd DEC 2025
Visit our website for more information: www2.mrc-lmb.cam.ac.uk/students/int...
Applications close on 2nd DEC 2025
Reposted by Derivery Lab - MRC LMB
We present a simple method to easily increase the imageable depth of an expansion microscopy gel on a typical inverted microscope ten-fold, using some carefully placed FEP film and a water dipping objective lens:
September 15, 2025 at 8:42 AM
We present a simple method to easily increase the imageable depth of an expansion microscopy gel on a typical inverted microscope ten-fold, using some carefully placed FEP film and a water dipping objective lens:
Reposted by Derivery Lab - MRC LMB
The final version of our multispectral microscopy manuscript is now online at Nature Photonics: www.nature.com/articles/s41...
The main additions are some further comparisons to yet more unmixing algorithms, in which we find that our algorithm is still the most accurate.
The main additions are some further comparisons to yet more unmixing algorithms, in which we find that our algorithm is still the most accurate.
September 16, 2025 at 7:43 AM
The final version of our multispectral microscopy manuscript is now online at Nature Photonics: www.nature.com/articles/s41...
The main additions are some further comparisons to yet more unmixing algorithms, in which we find that our algorithm is still the most accurate.
The main additions are some further comparisons to yet more unmixing algorithms, in which we find that our algorithm is still the most accurate.
We are very happy that the amazing PhD work of our previous PhD student, @akaashkumar.bsky.social is out in Nature Photonics!
🚨Publication alert🚨
My first, first-author paper is now out in @natphoton.nature.com! Our paper describes an iterative spectral unmixing algorithm and eight-channel camera-based hardware we developed enabling unmixing of low SNR live-cell data at video rates. www.nature.com/articles/s41...
My first, first-author paper is now out in @natphoton.nature.com! Our paper describes an iterative spectral unmixing algorithm and eight-channel camera-based hardware we developed enabling unmixing of low SNR live-cell data at video rates. www.nature.com/articles/s41...
Multispectral live-cell imaging with uncompromised spatiotemporal resolution - Nature Photonics
A tree-like arrangement of dichroic mirrors and multiple cameras coupled with an iterative spectral unmixing algorithm enables multispectral imaging of live cells in up to eight spectral channels with...
www.nature.com
September 18, 2025 at 10:45 AM
We are very happy that the amazing PhD work of our previous PhD student, @akaashkumar.bsky.social is out in Nature Photonics!
Reposted by Derivery Lab - MRC LMB
Great opportunity for a Research Support Officer to join @cellbiol-mrclmb.bsky.social, supporting @deriverylab.bsky.social in their studies of the molecular mechanisms behind receptor sorting in endosomes.
More info: www.nature.com/naturecareer...
Apply by 10 JUL
#ScienceJobs
More info: www.nature.com/naturecareer...
Apply by 10 JUL
#ScienceJobs
June 23, 2025 at 3:11 PM
Great opportunity for a Research Support Officer to join @cellbiol-mrclmb.bsky.social, supporting @deriverylab.bsky.social in their studies of the molecular mechanisms behind receptor sorting in endosomes.
More info: www.nature.com/naturecareer...
Apply by 10 JUL
#ScienceJobs
More info: www.nature.com/naturecareer...
Apply by 10 JUL
#ScienceJobs
🚨 JOB ALERT 🚨
We're hiring a Research Assistant – no PhD needed!
Join us to explore the molecular mechanisms of receptor sorting in endosomes.
Experience in protein expression/purification, cloning & cell culture desired 🧫🔬
Apply now 👉 www.nature.com/naturecareer...
#STEMCareers #ResearchJobs
We're hiring a Research Assistant – no PhD needed!
Join us to explore the molecular mechanisms of receptor sorting in endosomes.
Experience in protein expression/purification, cloning & cell culture desired 🧫🔬
Apply now 👉 www.nature.com/naturecareer...
#STEMCareers #ResearchJobs
June 23, 2025 at 1:00 PM
🚨 JOB ALERT 🚨
We're hiring a Research Assistant – no PhD needed!
Join us to explore the molecular mechanisms of receptor sorting in endosomes.
Experience in protein expression/purification, cloning & cell culture desired 🧫🔬
Apply now 👉 www.nature.com/naturecareer...
#STEMCareers #ResearchJobs
We're hiring a Research Assistant – no PhD needed!
Join us to explore the molecular mechanisms of receptor sorting in endosomes.
Experience in protein expression/purification, cloning & cell culture desired 🧫🔬
Apply now 👉 www.nature.com/naturecareer...
#STEMCareers #ResearchJobs
Reposted by Derivery Lab - MRC LMB
Emmanuel Derivery (@deriverylab.bsky.social in @cellbiol-mrclmb.bsky.social) speaks to @jcellsci.bsky.social about the motivations behind his career, the exciting field of protein design & advice for new Group Leaders.
Full interview: journals.biologists.com/jcs/article/...
#LMBintheNews
Full interview: journals.biologists.com/jcs/article/...
#LMBintheNews
April 16, 2025 at 11:03 AM
Emmanuel Derivery (@deriverylab.bsky.social in @cellbiol-mrclmb.bsky.social) speaks to @jcellsci.bsky.social about the motivations behind his career, the exciting field of protein design & advice for new Group Leaders.
Full interview: journals.biologists.com/jcs/article/...
#LMBintheNews
Full interview: journals.biologists.com/jcs/article/...
#LMBintheNews
Reposted by Derivery Lab - MRC LMB
In our latest interview, we hear from the 2024 @bscb-official.bsky.social Hooke Medal winner Emmanuel Derivery @deriverylab.bsky.social. Emmanuel tells us about his research, what winning the Hooke Medal means to him & his advice on building a successful lab.
journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
April 14, 2025 at 10:12 AM
In our latest interview, we hear from the 2024 @bscb-official.bsky.social Hooke Medal winner Emmanuel Derivery @deriverylab.bsky.social. Emmanuel tells us about his research, what winning the Hooke Medal means to him & his advice on building a successful lab.
journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
Reposted by Derivery Lab - MRC LMB
😊 Very happy to see this out! A real group effort from the Hyslop lab (@thecimr.bsky.social) including brilliant collaborations with
@knowleslab.bsky.social,
Vendruscolo lab, @michael-e-ward.bsky.social lab,
@deriverylab.bsky.social lab,
@profmarciniak.bsky.social lab
🎉🎉🎉
@knowleslab.bsky.social,
Vendruscolo lab, @michael-e-ward.bsky.social lab,
@deriverylab.bsky.social lab,
@profmarciniak.bsky.social lab
🎉🎉🎉
ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes - Nature Communications
Nixon-Abell et al. show that ANXA11 condensation on lysosomal membranes causes a coupled phase transition of the underlying lipids and mechanical stiffening of the overall ensemble involved in RNP gra...
www.nature.com
March 24, 2025 at 3:02 PM
😊 Very happy to see this out! A real group effort from the Hyslop lab (@thecimr.bsky.social) including brilliant collaborations with
@knowleslab.bsky.social,
Vendruscolo lab, @michael-e-ward.bsky.social lab,
@deriverylab.bsky.social lab,
@profmarciniak.bsky.social lab
🎉🎉🎉
@knowleslab.bsky.social,
Vendruscolo lab, @michael-e-ward.bsky.social lab,
@deriverylab.bsky.social lab,
@profmarciniak.bsky.social lab
🎉🎉🎉
Reposted by Derivery Lab - MRC LMB
Are you an undergraduate student considering a career in academic research?
Don’t miss the opportunity to gain hands-on experience at the LMB with our Student Placement Scheme – open now for applications!
Apply by 30th March.
More info: www2.mrc-lmb.cam.ac.uk/students/stu...
Don’t miss the opportunity to gain hands-on experience at the LMB with our Student Placement Scheme – open now for applications!
Apply by 30th March.
More info: www2.mrc-lmb.cam.ac.uk/students/stu...
March 4, 2025 at 9:48 AM
Are you an undergraduate student considering a career in academic research?
Don’t miss the opportunity to gain hands-on experience at the LMB with our Student Placement Scheme – open now for applications!
Apply by 30th March.
More info: www2.mrc-lmb.cam.ac.uk/students/stu...
Don’t miss the opportunity to gain hands-on experience at the LMB with our Student Placement Scheme – open now for applications!
Apply by 30th March.
More info: www2.mrc-lmb.cam.ac.uk/students/stu...
We are super proud of @lara-kruger.bsky.social who is leaving to start her own lab at
@institutcurie.bsky.social
- you're going to be missed in the Derivery lab!
@institutcurie.bsky.social
- you're going to be missed in the Derivery lab!
Congratulations to @lara-kruger.bsky.social, postdoc in @deriverylab.bsky.social in @cellbiol-mrclmb.bsky.social, who is leaving the LMB to establish her own research group at @institutcurie.bsky.social in Paris!
Best of luck to you Lara!
#LMBAlumni
Best of luck to you Lara!
#LMBAlumni
February 6, 2025 at 2:58 PM
We are super proud of @lara-kruger.bsky.social who is leaving to start her own lab at
@institutcurie.bsky.social
- you're going to be missed in the Derivery lab!
@institutcurie.bsky.social
- you're going to be missed in the Derivery lab!
Reposted by Derivery Lab - MRC LMB
Our automatic parameter-free deconvolution code is now 2–3× faster while still producing exactly the same results as before. If you want to try it out, we have a Google Notebook implementation available at beryl.mrc-lmb.cam.ac.uk/rlgc_notebook/. Manuscript WIP.
January 22, 2025 at 10:45 AM
Our automatic parameter-free deconvolution code is now 2–3× faster while still producing exactly the same results as before. If you want to try it out, we have a Google Notebook implementation available at beryl.mrc-lmb.cam.ac.uk/rlgc_notebook/. Manuscript WIP.
Congrats to @juliemiesch.bsky.social who was awarded a Postdoc Mobility grant by @snf-ch.bsky.social to support her research for two years. Her postdoc research will focus on the biophysical regulation of water buffering in the cell.
January 20, 2025 at 2:36 PM
Congrats to @juliemiesch.bsky.social who was awarded a Postdoc Mobility grant by @snf-ch.bsky.social to support her research for two years. Her postdoc research will focus on the biophysical regulation of water buffering in the cell.
Reposted by Derivery Lab - MRC LMB
How does tRNA-modifier #Elongator stabilize microtubules during asymmetric cell division?
Vicente Planelles Herrero @deriverylab.bsky.social et al find subcomplexes binding to microtubule ends & tubulin dimers, & enriching microtubules with polyglutamylated tubulin
www.embopress.org/doi/full/10....
Vicente Planelles Herrero @deriverylab.bsky.social et al find subcomplexes binding to microtubule ends & tubulin dimers, & enriching microtubules with polyglutamylated tubulin
www.embopress.org/doi/full/10....
January 15, 2025 at 4:04 PM
How does tRNA-modifier #Elongator stabilize microtubules during asymmetric cell division?
Vicente Planelles Herrero @deriverylab.bsky.social et al find subcomplexes binding to microtubule ends & tubulin dimers, & enriching microtubules with polyglutamylated tubulin
www.embopress.org/doi/full/10....
Vicente Planelles Herrero @deriverylab.bsky.social et al find subcomplexes binding to microtubule ends & tubulin dimers, & enriching microtubules with polyglutamylated tubulin
www.embopress.org/doi/full/10....
🚨 Paper Alert 🚨
Our preprint describing Elongator as a selective microtubule polymerase that rewrites PTMs on microtubules is now published! Check it out: www.embopress.org/doi/full/10....
Our preprint describing Elongator as a selective microtubule polymerase that rewrites PTMs on microtubules is now published! Check it out: www.embopress.org/doi/full/10....
Elongator is a microtubule polymerase selective for polyglutamylated tubulin | The EMBO Journal
imageimageElongator, an established tRNA-modifying complex, can also stabilize microtubules
during asymmetric cell division. This study shows that Elongator subcomplexes achieve
this by binding to mic...
www.embopress.org
January 17, 2025 at 9:46 AM
🚨 Paper Alert 🚨
Our preprint describing Elongator as a selective microtubule polymerase that rewrites PTMs on microtubules is now published! Check it out: www.embopress.org/doi/full/10....
Our preprint describing Elongator as a selective microtubule polymerase that rewrites PTMs on microtubules is now published! Check it out: www.embopress.org/doi/full/10....
Reposted by Derivery Lab - MRC LMB
Congrats to @akaashkumar.bsky.social who has won the PhD Award from the Cambridge Centre for Physical Biology for his work developing a novel microscopy system with @deriverylab.bsky.social & @jamesdmanton.bsky.social in @cellbiol-mrclmb.bsky.social.
www.physbiol.cam.ac.uk/akaash-kumar
#LMBintheNews
www.physbiol.cam.ac.uk/akaash-kumar
#LMBintheNews
December 16, 2024 at 3:19 PM
Congrats to @akaashkumar.bsky.social who has won the PhD Award from the Cambridge Centre for Physical Biology for his work developing a novel microscopy system with @deriverylab.bsky.social & @jamesdmanton.bsky.social in @cellbiol-mrclmb.bsky.social.
www.physbiol.cam.ac.uk/akaash-kumar
#LMBintheNews
www.physbiol.cam.ac.uk/akaash-kumar
#LMBintheNews
Congrats to @akaashkumar.bsky.social , a postdoc in the lab, for winning the PhD Award from the Cambridge Centre for Physical Biology. His PhD research worked on the development of a multispectral imaging system to image up to 8 fluorophores similtaneously for tackling complex biological questions!
December 11, 2024 at 11:24 AM
Congrats to @akaashkumar.bsky.social , a postdoc in the lab, for winning the PhD Award from the Cambridge Centre for Physical Biology. His PhD research worked on the development of a multispectral imaging system to image up to 8 fluorophores similtaneously for tackling complex biological questions!
Catching the blue-world up with the last 6 months of Derivery group shenanigans:
First up: in April Manu was the recipient of the 2024 Hooke Medal from BSCB!
First up: in April Manu was the recipient of the 2024 Hooke Medal from BSCB!
November 22, 2024 at 1:23 PM
Catching the blue-world up with the last 6 months of Derivery group shenanigans:
First up: in April Manu was the recipient of the 2024 Hooke Medal from BSCB!
First up: in April Manu was the recipient of the 2024 Hooke Medal from BSCB!
We are excited to be over here on BlueSky! @DeriveryLab on the other app.
a white cat is laying on its back on the floor and says `` hello . hello ... ''
ALT: a white cat is laying on its back on the floor and says `` hello . hello ... ''
media.tenor.com
November 21, 2024 at 4:39 PM
We are excited to be over here on BlueSky! @DeriveryLab on the other app.