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mhall98.bsky.social
Matthew Harry Hall
@mhall98.bsky.social
41 followers 73 following 1 posts
RNA biology x miRNAs x AGO proteins x RNA Therapeutics Ph.D Candidate @ Bartel Lab @ MIT x Whitehead
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bartellab.bsky.social
David Bartel's Lab @bartellab.bsky.social · Mar 15
Check out the latest study from our lab, led by @mhall98.bsky.social :
www.biorxiv.org/content/10.1... (1/2)
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mhall98.bsky.social
Matthew Harry Hall @mhall98.bsky.social · Mar 12
Pleased to share my recent work from the Bartel Lab! Some miRNAs recognize novel target sites called 3'-only sites, which pair to the miRNA 3' region but not to the seed. These sites direct mRNA repression in cells and are engaged by different mechanisms to seed sites
www.biorxiv.org/content/10.1...
Functional microRNA targeting without seed pairing
MicroRNAs (miRNAs) associate with Argonaute (AGO) proteins to serve as guides, directing binding to partially complementary sites in mRNAs, ultimately causing post-transcriptional repression. Compleme...
www.biorxiv.org
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