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Miguel Montez

@miguelmontez.bsky.social

220 followers 660 following 22 posts

Wellcome Trust ECA Fellow at the John Innes Centre. Studying Chromatin structure dynamics that adapt plants to their environment. 🌱

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Miguel Montez @miguelmontez.bsky.social · 29d

Delighted to share that I’ve been awarded the Wellcome Trust Early-Career Award 🙏 £1.4m over 5 years.
The start of an exciting new journey 🚀

John Innes Centre @johninnescentre.bsky.social · 29d

NEWS - Talented early-career researcher receives major @wellcometrust.bsky.social funding

The innovative research project of JIC early-career plant scientist, Dr @miguelmontez.bsky.social, has attracted a prestigious funding award from a global health charity.

www.jic.ac.uk/news/talente...

Talented early-career researcher receives major Wellcome Trust funding | John Innes Centre

The innovative research project of an early-career plant scientist at the John Innes Centre has attracted a prestigious funding award from a global health charity…

www.jic.ac.uk

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Miguel Montez @miguelmontez.bsky.social · 21d

Cheers

Miguel Montez @miguelmontez.bsky.social · 21d

Thank you 😁

Miguel Montez @miguelmontez.bsky.social · 28d

Thank you 😉

Miguel Montez @miguelmontez.bsky.social · 28d

Thanks! 😁

Miguel Montez @miguelmontez.bsky.social · 28d

Thank you, Sjon!

Miguel Montez @miguelmontez.bsky.social · 28d

Thank you so much, Jake! 👍

Miguel Montez @miguelmontez.bsky.social · 28d

Thank you, Tom 🍻

Miguel Montez @miguelmontez.bsky.social · 29d

I’m deeply grateful to the @wellcometrust.bsky.social for supporting my research, and to the John Innes Centre, my collaborators, mentors, and colleagues for their invaluable support.

Miguel Montez @miguelmontez.bsky.social · 29d

My project aims to understand the dynamics, regulation, and biological functions of the local #chromatin structure in the context of how plants 🌱 adapt to their #environment.

Miguel Montez @miguelmontez.bsky.social · 29d

This grant gives me the opportunity to build my group and develop exciting research, hosted by Prof @antdodd.bsky.social at the @johninnescentre.bsky.social
I will soon advertise one Postdoc position, stay tuned.

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Miguel Montez @miguelmontez.bsky.social · 29d

Delighted to share that I’ve been awarded the Wellcome Trust Early-Career Award 🙏 £1.4m over 5 years.
The start of an exciting new journey 🚀

John Innes Centre @johninnescentre.bsky.social · 29d

Talented early-career researcher receives major Wellcome Trust funding | John Innes Centre

The innovative research project of an early-career plant scientist at the John Innes Centre has attracted a prestigious funding award from a global health charity…

www.jic.ac.uk

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Reposted by Miguel Montez

Yiliang Ding @yiliangding.bsky.social · Aug 28

Super lucky to get the Faraday!Very grateful for the support from @johninnescentre.bsky.social @carolined2.bsky.social, my group and all the collaborators/friends🙏

John Innes Centre @johninnescentre.bsky.social · Aug 28

NEWS - Professor Yiliang Ding awarded prestigious Royal Society Faraday Discovery Fellowship

These long-term @royalsociety.org awards are worth £8m over 10 years to support exceptional mid-career research leaders in the UK. Congratulations @yiliangding.bsky.social 👏

👉 www.jic.ac.uk/press-releas...

Professor Yiliang Ding outside the John Innes Centre

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Reposted by Miguel Montez

UK Research and Innovation @ukri.org · Sep 3

Almost 50% of lab workers identify as neurodiverse.

So what difference could it make for research organisations to fully embrace neurodiversity in their workplace culture?

We supported the John Innes Centre to implement a project aiming to do just that 👇

John Innes Centre @johninnescentre.bsky.social · Aug 29

BLOG - Seven ingredients for a Neuroinclusive research organisation

In our latest #JICNeurodiversity blog, we reflect on the remarkable impact and success of our BBSRC @ukri.org funded “Understanding, Valuing and Celebrating Neurodiversity” project 🌈🧠

Watch full video: youtu.be/bwUEJju9XQ4?...

Understanding, Valuing and Celebrating Neurodiversity – Impact of our BBSRC Connecting Culture grant

YouTube video by John Innes Centre

youtu.be

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Miguel Montez @miguelmontez.bsky.social · Apr 17

What a fabulous work! A polyA "tailored" mechanism to enhance #mRNA vaccine efficiency via cytoplasmic re-adenylation. Huge impact on #RNAtherapeutics.
A demonstration of the scientific excellence of Polish research institutions.

iimcb.bsky.social @iimcb.bsky.social · Apr 16

🌐Our @nature.com paper is out! Researchers from IIMCB and other Polish institutions show how TENT5A boosts mRNA vaccine efficacy by stabilizing therapeutic mRNAs and enhancing antigen production. A step toward better therapies for cancer and beyond! 🧬

👉Read the story: bit.ly/3XYvQkI

#Nature #mRNA

IIMCB

bit.ly

Miguel Montez @miguelmontez.bsky.social · Mar 26

Physics of Life 2025 @physicsoflifeuk.bsky.social has been a fantastic meeting. To step forward into understanding #Biology it really is urgent to integrate #Biophysics, #Biochemistry, #StructuralBiology, #Computational modelling, #Theory, etc...
I'm very happy to be part of this community.

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Reposted by Miguel Montez

Sascha Laubinger @saschalaubinger.bsky.social · Mar 3

Please RT:
🌱 We’re hiring a Postdoc and a PhD student!
⏳ Application deadline: 17. March 2025
Join our lab and explore the role of alternative mRNA isoforms in drought stress and environmental adaptation in crops and Arabidopsis. Learn more and apply: www.lablaubinger.eu/Opportunities

Opportunities

www.lablaubinger.eu

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Reposted by Miguel Montez

Geng-Jen Jang @gjjang.bsky.social · Feb 28

Our paper has been published! We used in vivo single-particle tracking to demonstrate that the assembly of core FCA oligomers into functional macromolecular condensates.
Thanks to all the authors and colleagues!

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Miguel Montez @miguelmontez.bsky.social · Feb 26

Fantastic opportunity. Apply!

The Arabidopsis Information Resource (TAIR) @tairnews.bsky.social · Feb 26

"Postdoc in seed molecular biology and physiology at Institute of Biochemistry and Biophysics PAS, Warsaw, Poland
*Application Deadline: 3/31/2025"

Read more here: https://arabidopsis.org/news/jobs/view?file=Warsaw_2-25-25.pdf

#PlantSciJobs

Miguel Montez @miguelmontez.bsky.social · Feb 26

A very insightful work into #lncRNA parallel functions, U1-dependent #chromatin association, and alternative #polyA site selection.

I am delighted to be part of this work led by Szymon Swiezewski and Sebastian Sacharowski.

⚠️ Preprint
www.biorxiv.org/content/10.1...

Chromatin retained MUSHER lncRNA integrates ABA and DOG1 signalling pathways to enhance Arabidopsis seeds dormancy

Many plant lncRNAs regulate gene expression by binding to chromatin, but how they are retained at the target loci is unclear. We identify a new, chromatin-localized lncRNA - MUSHER , which activates t...

www.biorxiv.org

Miguel Montez @miguelmontez.bsky.social · Feb 22

Very nice! Congrats to all.

Reposted by Miguel Montez

Sascha Laubinger @saschalaubinger.bsky.social · Feb 21

Very happy to be part of this cool story showing that LUC7 proteins define two major classes of 5’SS in animals and plants! Thanks, Chris @daspliceisright.bsky.social and Connor, for reaching out to us!

Burge Lab @daspliceisright.bsky.social · Feb 20

Here is the research article, published today in Nature Communications:

www.nature.com/articles/s41...

LUC7 proteins define two major classes of 5′ splice sites in animals and plants - Nature Communications

Non-coding introns are excised from RNA transcripts of most eukaryotic genes by splicing. Here, Kenny et al. show that LUC7 proteins promote the splicing of different subsets of introns with distinct ...

www.nature.com

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Miguel Montez @miguelmontez.bsky.social · Feb 21

This has been part of a fantastic collaboration with @janhuemar.bsky.social @juliamaristany.bsky.social and @rcollepardo.bsky.social

And, it has opened super exciting future research directions.

Miguel Montez @miguelmontez.bsky.social · Feb 21

We hypothesize that these temperature-dependent dynamics alter the #chromatin structure from a modality active for #transcription to a state that can be #Polycomb silenced.

Miguel Montez @miguelmontez.bsky.social · Feb 21

Spoiler alert!
We found local nucleosome dynamics at the FLC locus in Arabidopsis 🌱 that:
(1) integrate a cold-induced silencing mechanism
(2) reveal H2A.Z incorporation preventing silencing by #PRC1 and #PRC2
(3) involve local/fine-scale 3D structural changes to the chromatin

Miguel Montez @miguelmontez.bsky.social · Feb 21

We found many interesting insights into the dynamic and structural nature of a PRC2 nucleation region/PRE.

Needless to say, this has a substantial impact on understanding the fundamental basis of epigenetic switches underpinning cell identity and responses to the #environment.

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