Lightnews — Scholar-powered news

Mick Milsom @milsommick.bsky.social · 8d

Surprising finding that standard chemo renders AML resistant to subsequent treatment with menin inhibitors. Published in @isehsociety.bsky.social journal Exp. Hem.: www.exphem.org/article/S030...

Upfront Menin-inhibitor resistance in multiply pretreated leukemias

10% of acute leukemias carry rearrangements of the KMT2A gene (Mixed-Lineage Leukemia-1, MLL-1). More than 80 fusion partners have been identified, and differences in fusion partner have been linked t...

www.exphem.org

1 4 13

Mick Milsom @milsommick.bsky.social · 12d

Part 2 of the joint EHA/ISEH session at #ISEH2025 Kumamoto: Zuzana Tothova on therapeutic targeting of cohesin-mutant myeloid malignancies @isehsociety.bsky.social

2 9

Mick Milsom @milsommick.bsky.social · 12d

Florian Perner elucidates the molecular mechanism behind resistance to menin inhibitors in AML at the EHA/ISEH joint symposium at #ISEH2025 Kumamoto @isehsociety.bsky.social

1 3

Mick Milsom @milsommick.bsky.social · 14d

A few tickets left for the #ISEH2025 meet the expert breakfast. Only $35 dollars each! @isehsociety.bsky.social

2 1

Mick Milsom @milsommick.bsky.social · 15d

Conference lunch #ISEH2025 in Kumamoto………drops the mic! @isehsociety.bsky.social

1 7

Mick Milsom @milsommick.bsky.social · 17d

Excited to be heading out to #ISEH2025 in Kumamoto @isehsociety.bsky.social

1 9

Mick Milsom @milsommick.bsky.social · Aug 7

Today is the last day to take advantage of early registration rates for #ISEH2025. Check out the amazing program and come join us. Bonus: register now and have the chance to win ISEH swag!

ISEH - International Society for Experimental Hematology @isehsociety.bsky.social · Aug 4

The Race to Register for #ISEH2025 🏯 is on! Register by 11:59 p.m. CT today, 4 August, to be entered into a drawing to win one ISEH Commemorative Swag Pack! Take advantage of the early registration rates before they expire this Thursday, 7 August. www.iseh.org/2025Registration

1 1 4

Mick Milsom @milsommick.bsky.social · Jul 26

T-minus two days to snag a talk slot at ISEH 2025 via a late-breaking abstract submission

ISEH - International Society for Experimental Hematology @isehsociety.bsky.social · Jul 21

🚨 There is ONE WEEK left to submit a late-breaking abstract for #ISEH2025 🏯! Submit your research by 28 July for a chance at a short talk or poster presentation. www.iseh.org/2025abstracts

3 5

Reposted by Mick Milsom

ISEH - International Society for Experimental Hematology @isehsociety.bsky.social · Jul 21

🚨 There is ONE WEEK left to submit a late-breaking abstract for #ISEH2025 🏯! Submit your research by 28 July for a chance at a short talk or poster presentation. www.iseh.org/2025abstracts

4 1

Mick Milsom @milsommick.bsky.social · Jul 22

Congrats Tiago. Looks really interesting

1

Mick Milsom @milsommick.bsky.social · Jul 2

Didn’t get your abstract submitted in time? Late breaking submission has just opened

ISEH - International Society for Experimental Hematology @isehsociety.bsky.social · Jul 2

It's not too late! The late-breaking call for abstracts for #ISEH2025 🏯 is now open. Submit your abstracts by 16 July for a chance to share your findings with world-leading scientists. www.iseh.org/2025abstracts

6 6

Mick Milsom @milsommick.bsky.social · Jun 27

Keynote by Wolf Reik starts off with a thought provoking/challenging message. Annual meeting of the German Association for Aging Research in Ulm

3

Mick Milsom @milsommick.bsky.social · Jun 26

Outstanding first talk at a conference for Yiwen Zhang at the annual meeting of the German Association for Aging Research…….very proud!

6

Mick Milsom @milsommick.bsky.social · Jun 11

Session 3: Therapy resistance
congress-apps.ehaweb.org/eha2025/en-G...

Index

congress-apps.ehaweb.org

1

Mick Milsom @milsommick.bsky.social · Jun 11

Session 2: Stem cells and development
congress-apps.ehaweb.org/eha2025/en-G...

Index

congress-apps.ehaweb.org

1

Mick Milsom @milsommick.bsky.social · Jun 11

Session 1: Epigenetics and Metabolism
congress-apps.ehaweb.org/eha2025/en-G...

Index

congress-apps.ehaweb.org

1 1 1

Mick Milsom @milsommick.bsky.social · Jun 11

EHA 2025 annual meeting attendees, we have a great line up of speakers for this year's Mol. Hem. Workshop in Milan. Note the change of date time from the usual slot. This year on Thu 12th, starting at 13:30 in Brown Hall 3. Links to session in the thread below (1/4)

1 1 8

Reposted by Mick Milsom

Grant Rowe @bloodandtime.bsky.social · May 27

Here is the first in a planned series of article commentaries in Experimental Hematology
@isehsociety.bsky.social - thanks to @challenlab.bsky.social and @lindemileslab.bsky.social!
www.exphem.org/article/S030...

Cell-extrinsic factors contribute toward myeloid-biased expansion in Tet2-mutant clonal hematopoiesis

Hematopoietic stem cells (HSCs) acquire somatic mutations throughout life, with the frequency of mutational incidence increasing with age [1]. Occasionally, certain mutations confer a fitness advantag...

www.exphem.org

3 9

Reposted by Mick Milsom

Louise Purton @louisepurton.bsky.social · May 23

Thanks to @lindemileslab.bsky.social and @challenlab.bsky.social (& team) for writing our first commentary for @isehsociety.bsky.social journal Experimental Hematology! Two recent papers on Clonal Hematopoiesis- want to learn more? Read the link here 👇🏻

Keisuke Ito @keisukeito-lab.bsky.social · May 23

Excited to see the first commentary in Experimental Hematology (@isehsociety.bsky.social)! Kudos to Aishwarya, Linde ‪@lindemileslab.bsky.social, and Grant @challenlab.bsky.social for highlighting recent papers in Exp Hem on cell-extrinsic factors in Tet2-mutant clonal hematopoiesis!! bit.ly/4k3pEAI

Cell-extrinsic factors contribute toward myeloid-biased expansion in Tet2-mutant clonal hematopoiesis

Hematopoietic stem cells (HSCs) acquire somatic mutations throughout life, with the frequency of mutational incidence increasing with age [1]. Occasionally, certain mutations confer a fitness advantag...

bit.ly

4 11

Reposted by Mick Milsom

ISEH - International Society for Experimental Hematology @isehsociety.bsky.social · May 29

We're kicking off our Interview Spotlight Series with the 2025 New Investigator Invited Speaker @shalinhnaik.bsky.social‬ Prof. Naik dives into his current work, career inspirations and life outside of the lab. Watch the interview on www.simplyblood.org

1 2

Reposted by Mick Milsom

Sally Lowell @cellysally.bsky.social · May 2

Reminder: deadline to apply for the Stem Cell Summer School is 30th May. And it's May already! So you have to apply this month!

A limited number of bursaries are available.

p.s. this year, the summer school coincides with the Spetses Armata Festival, so there will be a big party on the island 🙂

Stem Cell Summer School @stemcellsummer.bsky.social · Apr 7

The 2025 European Summer School in Stem Cell Biology and Regenerative Medicine will take place 12-19 Sept 2025, on the beautiful Greek island of Spetses.

Keep an eye on our website www.stemcellsummerschool.org for updates, or give us a follow 😀

Deadline for applications: 30th May 2025

Poster listing the faculty for the 2025 stem cell summer school on Spetses. Check our website (URL in bio) for full details.

11 6

Mick Milsom @milsommick.bsky.social · May 15

T-minus 4 days until the deadline for abstract submission (19th May)!!!!!!!! Check out the latest updates to the program for the @isehsociety.bsky.social annual meeting here:

ISEH - International Society for Experimental Hematology @isehsociety.bsky.social · May 12

Registration for #ISEH2025 🏯 is now open! Join your ISEH community from 24-27 September in Kumamoto, Japan to connect with brilliant minds from around the globe. Register by 7 August to secure the lowest rates. www.iseh.org/2025Registration

3 5

Reposted by Mick Milsom

ISEH - International Society for Experimental Hematology @isehsociety.bsky.social · May 13

The May #ExpHem issue is here! Explore the articles, including D816V KIT mutation induces mitochondrial morphologic and functional changes through BNIP3 downregulation in human myeloid cell lines ROSA and TF-1. www.exphem.org/current

2 1

Mick Milsom @milsommick.bsky.social · Apr 30

Just under two weeks to submit your work for presentation. Travel grants for trainees with top scoring abstracts. Check out the program to see the outstanding environment in which you would be showcasing your project as well as the training/networking activities.

ISEH - International Society for Experimental Hematology @isehsociety.bsky.social · Apr 29

Submit an abstract to #ISEH2025 🏯 by 12 May for a chance to present your work to your international community of hematology experts and innovators ✨ www.iseh.org/2025Abstracts

3 3

Reposted by Mick Milsom

Kate MacNamara @macnamaralab.bsky.social · Apr 15

Spotlight time! The Espin lab studies development and HSC emergence, aiming to harness inflammatory pathways for improving iPSC generation. @espinlab.bsky.social Super cool! 👇 #SimplyBlood #Hematopoiesis @isehsociety.bsky.social

ISEH - International Society for Experimental Hematology @isehsociety.bsky.social · Apr 14

This week on #SimplyBlood 🩸 we're featuring the @espinlab.bsky.social out of Iowa State University. Read more about their exciting research, biggest accomplishments, and the key to running a successful lab ➡️ www.simplyblood.org

2 4