miraburtscher.bsky.social
@miraburtscher.bsky.social
53 followers 51 following 2 posts
Predoc @savitski_lab @EMBL | Computational Biology @saezlab | Interested in functional proteomics and systems biology 🧫🧬
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miraburtscher.bsky.social
miraburtscher.bsky.social @miraburtscher.bsky.social · Jul 4
Big congrats to everyone involved - it was a blast! 🎊 If you're interested in #multiomics integration or #kidneyfibrosis, check it out! ⬇️
saezlab.bsky.social
Saez-Rodriguez Group @saezlab.bsky.social · Jun 27
The final version of our multi-omics study on kidney fibrosis is out now (tinyurl.com/kidneyfibMSB). Together w/ Pepperkok + Savitski labs @embl.org, we present a time-resolved #multiomics + computational network modeling approach in combination w/ phenotypic assays to study #kidneyfibrosis
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ebi.embl.org
EMBL-EBI @ebi.embl.org · Jul 22
How can we find out what’s really going on inside cells when we’re generating so much complex data?

CORNETO is an open-source tool that uses machine learning to turn tangled omics datasets into clear maps of how genes, proteins, and signalling pathways interact.

www.ebi.ac.uk/about/news/r... 🧪
CORNETO: machine learning to decode complex omics data
New tool combines biological knowledge with machine learning to help researchers extract meaningful insights from complex omics data.
www.ebi.ac.uk
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molsystbiol.org
Molecular Systems Biology @molsystbiol.org · Jul 3
integrated temporally resolved transcriptomic, proteomic, and secretomic profiling of human kidney mesenchymal cells from @savitski-lab.bsky.social @saezlab.bsky.social @miraburtscher.bsky.social identify dynamic changes upon TGF-beta stimulation ➡️ www.embopress.org/doi/full/10....
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miraburtscher.bsky.social
miraburtscher.bsky.social @miraburtscher.bsky.social · Jul 4
Big congrats to everyone involved - it was a blast! 🎊 If you're interested in #multiomics integration or #kidneyfibrosis, check it out! ⬇️
saezlab.bsky.social
Saez-Rodriguez Group @saezlab.bsky.social · Jun 27
The final version of our multi-omics study on kidney fibrosis is out now (tinyurl.com/kidneyfibMSB). Together w/ Pepperkok + Savitski labs @embl.org, we present a time-resolved #multiomics + computational network modeling approach in combination w/ phenotypic assays to study #kidneyfibrosis
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saezlab.bsky.social
Saez-Rodriguez Group @saezlab.bsky.social · May 23
Ever wondered which method to use to infer kinase activities from phosphoproteomics data? 💻💭Our revised comprehensive evaluation of kinase activity inference tools, done in collaboration with the Zhang lab @bcmhouston.bsky.social, is now out @natcomms.nature.com 🔬 tinyurl.com/4twuc6z4
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cp-trendsbiochem.bsky.social
Trends in Biochemical Sciences @cp-trendsbiochem.bsky.social · May 9
Online now - the Spotlight "Accelerating the stride toward functional #glycoproteomics" from @timveth.bsky.social and @nmriley.bsky.social.

#Glycoproteins #Glycoforms #Glycoprofiling #DQGlyco #Glycotime

authors.elsevier.com/a/1l3k53S6Gf...
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savitski-lab.bsky.social
Savitski Lab @savitski-lab.bsky.social · Apr 29
Want to know how the ligands interact with proteins beyond model cell lines, e.g., in tissues or bacteria? Interested in membrane targets? Check out our High-Throughput PELSA method which allows you do all these cool screenings for dozens of ligands within two hours! www.biorxiv.org/content/10.1...
High-throughput peptide-centric local stability assay extends protein-ligand identification to membrane proteins, tissues, and bacteria
Systematic mapping of protein-ligand interactions is essential for understanding biological processes and drug mechanisms. Peptide-centric local stability assay (PELSA) is a powerful tool for detectin...
www.biorxiv.org
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martingarridorc.bsky.social
Martin Garrido-Rodriguez @martingarridorc.bsky.social · Feb 10
Excited to share our new paper! If you’re interested in glycoproteomics, be sure to check it out 👇

Huge kudos to all coauthors, especially the amazing glycoteam: Clement, @miraburtscher.bsky.social, Isabelle, and Misha (@savitski-lab.bsky.social)!
savitski-lab.bsky.social
Savitski Lab @savitski-lab.bsky.social · Feb 10
We are very happy to present our work on N-glycoproteomics!🍬 Our method enables the selective enrichment and precise quantification of intact N-glycopeptides to explore the dynamics of glycosylation microheterogeneity.
www.nature.com/articles/s41...
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embl.org
EMBL @embl.org · Feb 10
Bacteria can influence how sugars modify proteins in the brain – shown for the first time by EMBL researchers.

In their study, the scientists describe a new method to study glycosylation systematically & quantitatively, leading to new biological insights. 🧪🧠📈

www.embl.org/news/science...
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miraburtscher.bsky.social
miraburtscher.bsky.social @miraburtscher.bsky.social · Feb 10
Excited to see this huge piece of work out 🎉 Congrats to everyone involved! If you ever wanted to read a 8in1 paper grab a cup of tea and enjoy 📖
savitski-lab.bsky.social
Savitski Lab @savitski-lab.bsky.social · Feb 10
We are very happy to present our work on N-glycoproteomics!🍬 Our method enables the selective enrichment and precise quantification of intact N-glycopeptides to explore the dynamics of glycosylation microheterogeneity.
www.nature.com/articles/s41...
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