Miranda Evans
@mirandaevans.bsky.social
Postdoc on Ancient Antibodies project. Interested in ancient cuisine, protein preservation, osteo, taphonomy. PhD from @cam-archaeology.bsky.social
5/5
🏺 This matters because alternate peptide sequences can lead to inaccurate protein taxonomy and archaeological interpretations. The Demodifier is fast and open source, enabling easy detection of MISPs.
📄 Paper: doi.org/10.1371/jour...
💻 GitHub: github.com/miranda-e/De...
🏺 This matters because alternate peptide sequences can lead to inaccurate protein taxonomy and archaeological interpretations. The Demodifier is fast and open source, enabling easy detection of MISPs.
📄 Paper: doi.org/10.1371/jour...
💻 GitHub: github.com/miranda-e/De...
January 13, 2026 at 10:17 AM
5/5
🏺 This matters because alternate peptide sequences can lead to inaccurate protein taxonomy and archaeological interpretations. The Demodifier is fast and open source, enabling easy detection of MISPs.
📄 Paper: doi.org/10.1371/jour...
💻 GitHub: github.com/miranda-e/De...
🏺 This matters because alternate peptide sequences can lead to inaccurate protein taxonomy and archaeological interpretations. The Demodifier is fast and open source, enabling easy detection of MISPs.
📄 Paper: doi.org/10.1371/jour...
💻 GitHub: github.com/miranda-e/De...
4/5
📊 The Demodifier was applied to a test dataset including 20 published studies of dental calculus and vessel residues, revealing that modification-induced sequence permutations occurred almost ten times more frequently than previously reported.
📊 The Demodifier was applied to a test dataset including 20 published studies of dental calculus and vessel residues, revealing that modification-induced sequence permutations occurred almost ten times more frequently than previously reported.
January 13, 2026 at 10:15 AM
4/5
📊 The Demodifier was applied to a test dataset including 20 published studies of dental calculus and vessel residues, revealing that modification-induced sequence permutations occurred almost ten times more frequently than previously reported.
📊 The Demodifier was applied to a test dataset including 20 published studies of dental calculus and vessel residues, revealing that modification-induced sequence permutations occurred almost ten times more frequently than previously reported.
3/5
💻 The Demodifier simulates all possible modification-induced sequence permutations caused by deamidation (NQ) and N-terminal pyroglutamic acid formation, and assigns lowest common taxonomic ancestors via the Unipept API.
💻 The Demodifier simulates all possible modification-induced sequence permutations caused by deamidation (NQ) and N-terminal pyroglutamic acid formation, and assigns lowest common taxonomic ancestors via the Unipept API.
January 13, 2026 at 10:11 AM
3/5
💻 The Demodifier simulates all possible modification-induced sequence permutations caused by deamidation (NQ) and N-terminal pyroglutamic acid formation, and assigns lowest common taxonomic ancestors via the Unipept API.
💻 The Demodifier simulates all possible modification-induced sequence permutations caused by deamidation (NQ) and N-terminal pyroglutamic acid formation, and assigns lowest common taxonomic ancestors via the Unipept API.
2/5🧵
🧪 Protein modifications such as deamidation and N-terminal pyroglutamic acid formation can change peptide sequences and affect taxonomic assignment in palaeoproteomics.
🧪 Protein modifications such as deamidation and N-terminal pyroglutamic acid formation can change peptide sequences and affect taxonomic assignment in palaeoproteomics.
January 13, 2026 at 10:06 AM
2/5🧵
🧪 Protein modifications such as deamidation and N-terminal pyroglutamic acid formation can change peptide sequences and affect taxonomic assignment in palaeoproteomics.
🧪 Protein modifications such as deamidation and N-terminal pyroglutamic acid formation can change peptide sequences and affect taxonomic assignment in palaeoproteomics.
2/5
🧪 Protein modifications such as deamidation and N-terminal pyroglutamic acid formation can change peptide sequences and affect taxonomic assignment in palaeoproteomics.
🧪 Protein modifications such as deamidation and N-terminal pyroglutamic acid formation can change peptide sequences and affect taxonomic assignment in palaeoproteomics.
January 13, 2026 at 10:00 AM
2/5
🧪 Protein modifications such as deamidation and N-terminal pyroglutamic acid formation can change peptide sequences and affect taxonomic assignment in palaeoproteomics.
🧪 Protein modifications such as deamidation and N-terminal pyroglutamic acid formation can change peptide sequences and affect taxonomic assignment in palaeoproteomics.
Thank you! I love making posters. The skull is a flap, which reveals CT scans when raised.
September 20, 2025 at 3:34 PM
Thank you! I love making posters. The skull is a flap, which reveals CT scans when raised.