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Reposted by Maximilian Lueckel

Maximilian Lueckel @mlueckel.bsky.social · 14d

Introducing FASTANS - Fast Targeted Functional Network Stimulation

🐍 Python implementation of the TANS approach (Lynch et al.).
🎯 Optimizes TMS coil placements for precise, personalized network targeting within minutes! 🚀

Code, instructions, and example data: github.com/mlueckel/FAS...

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Jingnan Du @jingnandu.bsky.social · 12d

Our new paper is out now in Neuron! 🎉 With @vaibhavtripathi.bsky.social @maxwellelliott.bsky.social Joanna Ladopoulou, Wendy Sun, Mark Eldaief, and Randy Buckner

Paper link: www.sciencedirect.com/science/arti...

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Maximilian Lueckel @mlueckel.bsky.social · 14d

Introducing FASTANS - Fast Targeted Functional Network Stimulation

🐍 Python implementation of the TANS approach (Lynch et al.).
🎯 Optimizes TMS coil placements for precise, personalized network targeting within minutes! 🚀

Code, instructions, and example data: github.com/mlueckel/FAS...

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Maximilian Lueckel @mlueckel.bsky.social · Sep 1

Optional: one score to guide choices – weight metrics into a composite map that ranks candidate placements.

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Maximilian Lueckel @mlueckel.bsky.social · Sep 1

Plan early: explore targeting feasibility & hardware requirements (e.g., focal depth) on MNI templates or open-access datasets even before you collect individual MRIs.

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Maximilian Lueckel @mlueckel.bsky.social · Sep 1

Integrates nicely with other software: export selected placements to BabelBrain, k-Wave, or k-Plan for simulation and to Localite or BrainSight for neuronavigation.

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Maximilian Lueckel @mlueckel.bsky.social · Sep 1

Click to choose a spot, preview the transducer placement and a simplified acoustic focus, then export the placement for validation.

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Maximilian Lueckel @mlueckel.bsky.social · Sep 1

What it shows for every scalp point: distance to target, straight-path intersection with target, required transducer tilt, skin-skull angle, skull thickness – so you can quickly spot promising transducer placements. Some examples:

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Maximilian Lueckel @mlueckel.bsky.social · Sep 1

🎯 Meet 𝐏𝐥𝐚𝐧𝐓𝐔𝐒: a fast, open-source tool to pick where to place a transducer for transcranial ultrasonic stimulation (TUS) on an individual head – before you run heavy simulations.

Paper: doi.org/10.1016/j.br...

Code & instructions: plan-tus.org

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Deng Pan @dengpan.bsky.social · Aug 28

🚨We believe this is a major step forward in how we study hippocampus function in healthy humans.

Using novel behavioral tasks, fMRI, RL & RNN modeling, and transcranial ultrasound stimulation (TUS), we demonstrate the causal role of hippocampus in relational structure learning.

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Andreas Horn @andreashorn.org · Aug 22

🚨 New preprint out! 🚨
“Translating the Transcriptome: A Connectomics Approach for Gene-Network Mapping and Clinical Application”
🔗 doi.org/10.1101/2025...

🧵 A short thread:

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Johannes Algermissen @johalgermissen.bsky.social · Aug 20

Very happy to share my first preprint from @oxexppsy.bsky.social @oxneuro.bsky.social ! We (me + co-first authors @lilweb.bsky.social @mirunarascu.bsky.social + PI @mkflugge.bsky.social + many others) used transcranial focused ultrasound stimulation (TUS/tFUS/LIFU) of the human amygdala ... (1/15)

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Rick Betzel @richardfbetzel.bsky.social · Aug 10

Personalized Adaptive Cortical Electro-stimulation (PACE) in Treatment-Resistant Depression

Punchline: PERSONALIZED network neuroscience works.

*Easily* the most important paper I’ve been part of.

Read the manuscript for details. Watch the movies for *amazing* testimonial.

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Maximilian Lueckel @mlueckel.bsky.social · Aug 10

🤯🤯🤯

Damien Fair @drdamienfair.bsky.social · Aug 10

I still get chills

Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts

Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE

see videos, read paper, follow thread
doi.org/10.31234/osf...

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Rodrigo Braga @rodbraga.bsky.social · Aug 5

🚨 New Preprint 🚨

Targeting intracranial electrical stimulation (ES) to network regions defined within individuals causes network-level effects

By Cyr et al.

***
Q: Can we use individualized network maps from precision fMRI to modulate a targeted network via intracranial ES?

A: Yes!

🧵:

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Eva Feredoes @evalab.bsky.social · Jul 23

What is the best way to advance a challenging-yet-inferentially-powerful combination of neurostimulation and neuroimaging? Come to Cancun to find out! Join us for the 3rd International Concurrent TMS-fMRI Workshop September 15-17 *literally* by the beach: www.tmsfmriworkshop.org

www.tmsfmriworkshop.org

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Desmond Oathes, PhD @desmondoathes.bsky.social · Jul 22

Are you a TMS/fMRI researcher? Join us this September in Cancun! www.tmsfmriworkshop.org

www.tmsfmriworkshop.org

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Desmond Oathes, PhD @desmondoathes.bsky.social · Jul 22

functional connectivity proximity not associated with clinical response in N>500 MDD patients: www.biorxiv.org/content/10.1...

Proximity to an SGC-DLPFC Individualized Functional Target and outcomes in large rTMS clinical trials for Treatment-Resistant Depression

Background Targeting methods for repetitive transcranial magnetic stimulation (rTMS) in patients with depression now include the use of individual functional scans to target specific functional connec...

www.biorxiv.org

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Brain Networks @brainnetleipzig.bsky.social · Jul 2

🚨 New paper alert from Weise et al.!

"A leadfield-free optimization framework for transcranially applied electric currents"

🔋 Optimize TES, TIS, ECT & TTFields without fixed leadfields
🧠 Electrode placement adapts to individual anatomy
💻 Now available in SimNIBS!

doi.org/10.1016/j.co...

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Maximilian Lueckel @mlueckel.bsky.social · Jun 28

If you're interested in the concurrent use of transcranial magnetic stimulation (TMS) and functional magnetic resonance imaging (fMRI), check out our consensus guidelines, now officially out in @natprot.nature.com

#TMS #fMRI

www.nature.com/articles/s41...

Consensus guidelines for the use of concurrent TMS-fMRI in cognitive and clinical neuroscience - Nature Protocols

We present best practice guidelines for the use of concurrent TMS-fMRI, experimental design, technical requirements and data interpretation, illustrated via 12 use cases.

www.nature.com

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Annie G. Bryant @anniegbryant.bsky.social · May 4

🎨🧑‍🎨 Looking for a tool to visualize subcortical/thalamic data in 2D? Check out this python-based package I put together (subcortex-visualization on PyPI), plus a guide for creating your own custom atlas meshes and vector graphics! All feedback/tips welcome 😊

anniegbryant.github.io/subcortex_vi...

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Eva Feredoes @evalab.bsky.social · Mar 21

"...pleased to inform you that your article, "Consensus guidelines for the use of concurrent TMS-fMRI in cognitive and clinical neuroscience", has now been accepted and sent to our Production department and should soon be published in Nature Protocols."⚡🎈🤘 OG preprint here: osf.io/preprints/ps...

OSF

osf.io

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Maximilian Lueckel @mlueckel.bsky.social · Feb 18

Congratulations - this is fantastic news! Hope to get in touch and collaborate on personalized precision neuromodulation using TMS and focused ultrasound 🤩

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Caterina Gratton @caterinagratton.bsky.social · Nov 22

fMRI network measures are affected by sampling error 🎲, physiological artifacts 💗, arousal 👀, and task state 🎞️. We argue that a major challenge in studies of 🧠 network dynamics is distinguishing between these sources of variability.
A 🧵 …

Pyramid showing relative influence of non-neural (sampling variability, physiology, head motion) and neural (arousal, task state, spontaneous cognition) effects on functional connectivity

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