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Reposted by Max Planck Institute for Infection Biology

Max Planck Institute for the Science of Light (MPL) @mpi-scienceoflight.bsky.social · 19h

With deep sadness, we share that Prof. Jochen Guck, Director at the Max Planck Institute for the Science of Light passed away on October 3. His visionary work bridged physics and medicine. We have lost a brilliant scientist and dear friend.

mpl.mpg.de/news/article...
@fau.de

📸 Stephan Spangenberg

Professor Jochen Guck, Director at the Max Planck Institute for the Science of Light (MPL), He headed the division “Cell Physics” at MPL and the Max-Planck-Zentrum für Physik und Medizin (MPZPM).

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Max-Planck-Gesellschaft @maxplanck.de · 22h

Chemistry #NobelPrize 2025 for 'rooms in a hotel for molecules'! 😊Huge Congratulations to Susumu Kitagawa, Richard Robson & Omar Yaghi, winners of the 2025 Chemistry #NobelPrize for their transformative metal-organic frameworks research! 🥳

Nobel Prize in Chemistry 2025

The Nobel Prize in Chemistry 2025 was awarded to Susumu Kitagawa, Richard Robson and Omar M. Yaghi “for the development of metal-organic frameworks.”

www.nobelprize.org

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Max-Planck-Gesellschaft @maxplanck.de · 1d

Quantum wins the (Nobel) day! 😊 Congratulations to John Clarke, Michel Devoret & John Martinis — winners of the 2025 #NobelPrize in #Physics! 🥳 Their groundbreaking work on macroscopic #quantum tunnelling & circuit quantization has reshaped our understanding of the quantum world. ⚛️🌌

Physics Nobel: Three win prize for paving way for very powerful computers

The announcement was made by the Royal Swedish Academy of Sciences in Stockholm.

www.bbc.com

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EARA @eara.eu · 2d

The 2025 Nobel Prize in Physiology or Medicine was awarded today to three researchers for discovering how the immune system is kept in check, based on studies in mice. #NobelPrize #NobelPrizelaureates #NobelPrize2025 #medicine #science #AnimalReseach #mice
Read more: www.eara.eu/post/mice-st...

Mice studies were key for 2025 Nobel Prize research

The 2025 Nobel Prize in Physiology or Medicine was awarded to three researchers — Shimon Sakaguchi, Mary E. Brunkow and Fred Ramsdell — for discovering how the immune system is kept in check, based…

www.eara.eu

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Max-Planck-Gesellschaft @maxplanck.de · 2d

Huge congratulations to this year's winners of the #NobelPrize in Physiology or Medicine: Mary Brunkow, Fred Ramsdell & Shimon Sakaguchi! 🏆The trio's groundbreaking work on peripheral immune tolerance is paving the way for crucial new treatments for cancer & autoimmunity. 🧬

Nobel prize in medicine awarded to scientists for immune system research

Mary E Brunkow, Fred Ramsdell and Shimon Sakaguchi worked on how the immune system can be prevented from harming the body

www.theguardian.com

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Felix M Key @keyfm.bsky.social · 8d

Great to see the preprint & code out. Large scale within host evolution analysis made easy. Happy that we could contribute to the development. Kudos to all involved including @i-light-maka.bsky.social & @mfenk.bsky.social from the Key lab.

Tami Lieberman @contaminatedsci.bsky.social · 9d

Precisely calling mutations across hundreds of bacterial isolates has been hard, requiring manual filtering and expertise.

Until now, using AccuSNV.

Herui Liao trained an ML model based on our previous meticulously called SNVs.
www.biorxiv.org/content/10.1...

High-accuracy SNV calling for bacterial isolates using deep learning with AccuSNV

Accurate detection of mutations within bacterial species is critical for fundamental studies of microbial evolution, reconstructing transmission events, and identifying antimicrobial resistance mutati...

www.biorxiv.org

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Max Planck Institute for Infection Biology @mpiib-berlin.mpg.de · 13d

📢 Voices in Infection Biology
Join us next week for a talk by Boris Striepen @upenn.edu, hosted by Elena Levashina.

🗓️ Wednesday, October 1
🕓 2 pm
📍 on-site seminar (Berlin)

Event info: www.mpiib-berlin.mpg.de/events/42891...

Why do parasites have sex,
and how does it work?
Boris Striepen

October 1
2 PM
MAX PLANCK INSTITUTE
FOR INFECTION BIOLOGY, BERLIN

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Reposted by Max Planck Institute for Infection Biology

Max Planck Institute for the Science of Light (MPL) @mpi-scienceoflight.bsky.social · 13d

Researchers from #MPZPM and @mpiib-berlin.mpg.de have now compared the ratio of nuclear and cytoplasmic density in different organisms and come to a surprising conclusion: the cell nucleus in eukaryotes is less dense than the rest of the cell.

👉 mpzpm.mpg.de/news/news-de...

#Physics #Medicine

$A cell nucleus reconstituted in vitro in Xenopus laevis (African clawed frog) egg extract. Left image shows a fluorescence image where DNA has been stained and right image shows a density map of the same nucleus aquired using Optical Diffraction Tomography (ODT).$

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Max-Planck-Gesellschaft @maxplanck.de · 19d

Truly chuffed for our fearless food physicists @mpipks.bsky.social + collabs from AT @istaresearch.bsky.social, IT & ES who won this year’s Ig Nobel - the #NobelPrize of hearts❤️for cracking the science of perfect pasta !🍝Kudos to all for intrepidly consuming lots of cheese in the name of science!😋

The Secret to a Smooth Pasta Sauce Wins Ig Nobel Prize

Italian researchers studied how the ingredients of the traditional Roman dish cacio e pepe emulsify into a creamy sauce, winning the 2025 Physics Ig Nobel Prize.

www.the-scientist.com

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Max-Planck-Gesellschaft @maxplanck.de · 21d

Open Call for Expressions of Interest: become a Max Planck Director & redefine what’s possible in science! We offer scientific independence, long-term stable funding & exceptional infrastructure. Lead your own department & open new frontiers of research. Apply by 31 Oct 2025 → www.mpg.de/directors

Directors

The Max Planck Society offers Directors a unique platform for groundbreaking research and leadership in diverse scientific fields.

www.mpg.de

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Max Planck Institute for Infection Biology @mpiib-berlin.mpg.de · 20d

📃 New paper alert!
The Zychlinsky Lab and @raunser-lab.bsky.social identified the first protein that converts chromatin into an immune effector: Myeloperoxidase transforms chromatin into neutrophil extracellular traps. Now published in @nature.com:
www.nature.com/articles/s41...

Myeloperoxidase transforms chromatin into neutrophil extracellular traps - Nature

Myeloperoxidase, a highly expressed neutrophil protein, disassembles nucleosomes, facilitating neutrophil extracellular trap (NET) formation, and binds stably to NETs extracellularly.

www.nature.com

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Reposted by Max Planck Institute for Infection Biology

Tobias Raisch @traisch.bsky.social · 20d

We just published this paper of which I am immensely proud: www.nature.com/articles/s41...

In the study, we uncover how the enzyme MPO disassembles #nucleosomes in a process called NETosis, a funky mechanism of #neutrophils to kill #pathogens that you might have never heard of.

Let's dive in... 🧵

Myeloperoxidase transforms chromatin into neutrophil extracellular traps - Nature

Myeloperoxidase, a highly expressed neutrophil protein, disassembles nucleosomes, facilitating neutrophil extracellular trap (NET) formation, and binds stably to NETs extracellularly.

www.nature.com

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Max Planck Institute for Infection Biology @mpiib-berlin.mpg.de · 26d

#Job opportunity
The Key Lab @keyfm.bsky.social is looking for a #postdoc in evolutionary genetics - join a young team in the heart of #Berlin to investigate the evolution of ancient microbial pathogens.

⏰ Deadline: October 17
📌 More info and how to apply: www.mpiib-berlin.mpg.de/2193291/job_...

Max Planck Institute for Infection Biology

Postdoc in Evolutionary Genetics

Job Offer

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Max Planck Institute for Infection Biology @mpiib-berlin.mpg.de · Sep 8

📢 Voices in Infection Biology
☀️ We're back from summer break with a talk by Jan Skotheim from @stanford.edu, kindly hosted by @simonereber.bsky.social.

🗓️ Wednesday, September 10
🕓 4 pm
📍 on-site seminar (Berlin)

Event info: www.mpiib-berlin.mpg.de/events/42144...

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Max Planck Institute for Infection Biology @mpiib-berlin.mpg.de · Aug 20

(4/4) Finally, someone needs to take care of the #mosquitos. Twelve lab technicians and students work around 90 hours each week to maintain our #insectary - that's 4,680 hours each year. All these hours lay the groundwork for our #malaria research 🦟

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Max Planck Institute for Infection Biology @mpiib-berlin.mpg.de · Aug 20

(3/4) But sugar alone is not enough to breed #mosquitos. Females need to feed on a tiny drop of #blood (1-10 µL) to produce eggs, but this amount adds up!

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Max Planck Institute for Infection Biology @mpiib-berlin.mpg.de · Aug 20

(2/4) Our #mosquitos are hungry: Females and males in our insectary consume around 40 kilograms of sugar each year.

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Max Planck Institute for Infection Biology @mpiib-berlin.mpg.de · Aug 20

🦟 Today is #worldmosquitoday! It's a good opportunity to show what it takes to rear Anopheles mosquitos for our #malaria research.
First, let's look at how many mosquitos are bred in the Levashina Lab each year.
Check out the following posts to learn what it takes to keep them happy! (1/4) 👇

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Max Planck Institute for Infection Biology @mpiib-berlin.mpg.de · Aug 15

🚨 Paper alert!
Check out the latest work from the Reber Lab 📌 New research by @simonereber.bsky.social and @biswashere.bsky.social, now published in @natcomms.nature.com 🥳

Simone Reber @simonereber.bsky.social · Aug 15

FINALLY! Challenging to publish but we believe it is an important discovery: rdcu.be/eATFz

💚 Thanks to the team ‪@biswashere.bsky.social‬, Omar Muñoz, ✨Q✨ C. Hoege, B. Lorton, R. Nikolay ‪@matthewkraushar.bsky.social‬ @dshechter.bsky.social @gucklab.bsky.social @vasilyzaburdaev.bsky.social‬ 💚

Conserved nucleocytoplasmic density homeostasis drives cellular organization across eukaryotes

Nature Communications - Cells can regulate their mass density. Here, the authors demonstrate how eukaryotes establish and maintain a lower density in the nucleus than in the cytoplasm via pressure...

rdcu.be

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Reposted by Max Planck Institute for Infection Biology

Max-Planck-Gesellschaft @maxplanck.de · Aug 12

So intriguing! Researchers have isolated the genetic material of a prehistoric #plague pathogen from a 4,000-year-old sheep tooth, marking the first detection outside human remains & reshaping our view of early disease spread. www.mpg.de/25157082/080... @mpi-eva-leipzig.bsky.social #yersiniapestis

Pathogen discovered in 4,000-year-old sheep tooth

In the late Neolithic and Bronze Ages, sheep were apparently involved in the spread of an early form of the plague.

www.mpg.de

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Felix M Key @keyfm.bsky.social · Aug 11

First paper of the Key lab is out! We present the first prehistoric Y. pestis genome from a domesticated animal - a sheep - providing evidence that domestication elevated human infection risk with plague thousands of years ago. authors.elsevier.com/sd/article/S...

ScienceDirect.com | Science, health and medical journals, full text articles and books.

authors.elsevier.com

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Max Planck Institute for Infection Biology @mpiib-berlin.mpg.de · Aug 11

This was an interdisciplinary effort, enabled by experts from @mpi-eva-leipzig.bsky.social, @harvard.edu, Seoul National University, Ural & Altai University and @uarkansas.bsky.social. Congratulations to all of you!

For a summary check out our press release: www.mpiib-berlin.mpg.de/livestock-in...

Livestock played a role in prehistoric plague infections

Around 5,000 years ago, a mysterious form of plague spread throughout Eurasia, only to disappear 2,000 years later. Known only from ancient DNA, this enigmatic ‘LNBA plague’ lineage has left scientist...

www.mpiib-berlin.mpg.de

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Max Planck Institute for Infection Biology @mpiib-berlin.mpg.de · Aug 11

Ancient Yersinia pestis genome discovered in 4,000-year-old sheep tooth sheds new light on a mysterious infectious disease that plagued prehistoric Eurasia. New research by @keyfm.bsky.social and @i-light-maka.bsky.social now published in @cellpress.bsky.social: www.cell.com/cell/fulltex...

Bronze Age Yersinia pestis genome from sheep sheds light on hosts and evolution of a prehistoric plague lineage

A Yersinia pestis genome from a Bronze Age domesticated sheep provides insight into the host range, evolution, and possible transmission scenarios of an ancient lineage of the plague-causing bacteria,...

www.cell.com

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Reposted by Max Planck Institute for Infection Biology

Max-Planck-Gesellschaft @maxplanck.de · Aug 1

Director at Max Planck - a unique position! The Open Call for Expressions of Interest in Max Planck Directorships is open now and can be submitted by the 31st of October 2025. ➡️ mpg.de/directors - Please share the Open Call among potential candidates.

Open Call for Expressions of Interest in Max Planck Directorships:
Expressions of interest can be submitted until 31 October 2025.

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Max Planck Institute for Infection Biology @mpiib-berlin.mpg.de · Jul 4

Silvia Portugal, our Lise Meitner Group Leader, was appointed an honorary professor at the #Charité –Universitätsmedizin #Berlin. We are happy to strengthen our relationship with our neighbors on campus. Congratulations, Silvia! Many thanks also to Prof. Spranger, the dean of the Charité.

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