Lightnews — Scholar-powered news

MRC Laboratory of Medical Sciences @mrc-lms.bsky.social · 1d

New work from @drdeclanoregan.bsky.social and his lab has uncovered previously unknown links between our genes and heart shape

This was achieved by comparing the genetics and heart structures of over 40,000 people!

To read more follow the link!

First 3D genetic mapping of the heart uncovers genes implicated in sudden death

New research has identified previously unknown links between genes and heart shape. By analysing genetic data from over 40,000 UK Biobank participants, researchers at the MRC Laboratory of Medical Sci...

lms.mrc.ac.uk

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MRC Laboratory of Medical Sciences @mrc-lms.bsky.social · 2d

Just launched: the 1st video in our 6-part Chain Florey Clinician Scientist series at LMS!

Professor Declan O’Regan shares how we support early career clinicians bridging discovery and experimental medicine.

Find out more: lms.mrc.ac.uk/work-and-stu...

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MRC Laboratory of Medical Sciences @mrc-lms.bsky.social · 6d

The LMS has achieved Gold LEAF accreditation for sustainability! 🏅

From smart lab booking systems to energy-saving tech and zero-waste practices, we’re working hard to cut our environmental footprint while supporting world-class research! 🌍

#Sustainability #LEAF #GoldAward

LMS receives gold award for sustainability

Achieving Gold LEAF accreditation marks a significant milestone in our commitment to making research at the MRC Laboratory of Medical Sciences (LMS) more sustainable and signals the start of an ongoin...

lms.mrc.ac.uk

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Reposted by MRC Laboratory of Medical Sciences

cniostopcancer.bsky.social @cniostopcancer.bsky.social · 6d

#CFM_MolCellAging: session VI with:

Adam Antebi @antebilab.bsky.social @mpiage.bsky.social
Sheila Stewart @washumedicine.bsky.social
Jesús Gil at @mrc-lms.bsky.social
Manuel Serrano @altoslabs.bsky.social

🤝With support of @caixaresearch.bsky.social

Registration: http://bit.ly/4kOyYch

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MRC Laboratory of Medical Sciences @mrc-lms.bsky.social · 7d

🧬🐛 Meet your worm avatar.

What if we could use tiny worms to find treatments for thousands of rare genetic diseases?

New research from the LMS shows it’s possible – cheaply, quickly, and at scale.

#RareDisease #DrugDiscovery #Science #WormAvatars #Biotech

Meet your worm avatar: How microscopic worms are helping find new drugs for rare diseases

New research from the MRC Laboratory of Medical Sciences (LMS) provides a powerful, scalable method for finding treatments for rare genetic diseases using tiny, transparent worms.

lms.mrc.ac.uk

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MRC Laboratory of Medical Sciences @mrc-lms.bsky.social · 8d

As part of their DAISY study they enrolled over 900 women with #PCOS to help them better understand the role hormones play in PCOS.

Next they hope to enroll women without PCOS to see how they differ to those with the condition.

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MRC Laboratory of Medical Sciences @mrc-lms.bsky.social · 8d

September is #PCOSAwarenessMonth

#PolycysticOvarianSyndrome #PCOS is one of the LMS' translational targets.

Our director @wiebkearlt.bsky.social and her #ChainFlorey PhD Student @ekamelson.bsky.social have led work that has shed light on PCOS and shaped policy

www.monash.edu

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MRC Laboratory of Medical Sciences @mrc-lms.bsky.social · 9d

Today is World Heart Day!

Over the last year our researchers have discovered more about how our hearts age, developed new methods to diagnose and predict heart disease and were awarded professorships from @thebhf.bsky.social

We look forward to seeing what our researchers do in the coming year!

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Reposted by MRC Laboratory of Medical Sciences

Helena Cocheme @cochemelab.bsky.social · 13d

Arrived in Alicante, and excited for this year’s #EDRC2025! 🪰🧪🔬🧫🥼🧬🪰 The #LMS is well represented at the meeting - catch us at our talk/poster presentations!

#Drosophila #Redox #Ageing #DiseaseModels #Cancer #Obesity

@mrc-lms.bsky.social

EDRC2025 @edrc2025.bsky.social · 14d

Only a few hours left before our meeting starts! Are you travelling to #EDRC2025 now? Let us know by using the oficial #EDRC2025 hashtag!

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MRC Laboratory of Medical Sciences @mrc-lms.bsky.social · 19d

This week is Postdoc Appreciation Week, so we’d like to say a huge thank you to our incredible postdoc committee!

Through the committee our postdocs have gained access to career support, in and out of academia, as well as the opportunity to build a network within the LMS.

#NPAW2025 #Postdoc

A collage of 9 of our postdoc committee members

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Reposted by MRC Laboratory of Medical Sciences

Michelle Percharde @mpercharde.bsky.social · 19d

Come be our head of bioinformatics at @mrc-lms.bsky.social !

Our bioinformatics team are closely involved with lots of interesting science and we love working with them. Topics inc. development, cancer, metabolism, aging, TEs (my favourite of course 😜) #TEsky lms.mrc.ac.uk/work/vacanci...

Head of Bioinformatics - MRC Laboratory of Medical Sciences

We are recruiting for a Head of Bioinformatics to lead our Bioinformatics facility

lms.mrc.ac.uk

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MRC Laboratory of Medical Sciences @mrc-lms.bsky.social · 26d

Congratulations to all the people who worked on and supported this work:
@dmartimarti.bsky.social
@cochemelab.bsky.social
@kaletalab.bsky.social
@alexisbarr.bsky.social
@frezzalab.bsky.social
@imperialcollegeldn.bsky.social
@cecad.bsky.social
@cp-cellsystems.bsky.social
@leverhulme.ac.uk

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MRC Laboratory of Medical Sciences @mrc-lms.bsky.social · 26d

Can microbes enhance chemotherapy?

A new paper from the LMS shows how the tumour-associated microbiome can impact the efficacy of chemotherapy drugs.

#medsky #cancer #biomed

Chemotherapy modulation by a cancer-associated microbiota metabolite

Martinez-Martinez et al. combine a host-microbe-drug-nutrient screen with multi-omics to reveal how the cancer-associated microbiota modulates chemotherapy. They identify 2-methylisocitrate, a microbi...

www.cell.com

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MRC Laboratory of Medical Sciences @mrc-lms.bsky.social · 26d

Congratulations to all the people who worked on and supported this work:
@dmartimarti.bsky.social
@cochemelab.bsky.social
@kaletalab.bsky.social
@alexisbarr.bsky.social
@frezzalab.bsky.social
@imperialcollegeldn.bsky.social
@cecad.bsky.social
@cp-cellsystems.bsky.social
@leverhulme.ac.uk e.ac.uk

e.ac.uk

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Reposted by MRC Laboratory of Medical Sciences

Helena Cocheme @cochemelab.bsky.social · 28d

🚨New paper published today on cancer bugs and drugs!🚨

“Chemotherapy modulation by a cancer-associated microbiota metabolite”

Congrats to the Cabreiro lab on this exciting study!
#Cancer #Microbiome #Metabolism #Chemotherapy
#MRC_LMS #ImperialCollege #CECAD_Cologne

www.cell.com/cell-systems...

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MRC Laboratory of Medical Sciences @mrc-lms.bsky.social · Sep 4

We’re seeking a highly skilled and motivated candidate to lead the LMS Bioinformatics Facility.

Find out more and apply now by following the link below!

#Bioinformatics #Hiring #NowHiring #CareerOpportunities #Jobs

Head of Bioinformatics - MRC Laboratory of Medical Sciences

We are recruiting for a Head of Bioinformatics to lead our Bioinformatics facility

lms.mrc.ac.uk

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Reposted by MRC Laboratory of Medical Sciences

Imperial Medicine @imperialmed.bsky.social · Sep 3

Why do some hearts age faster than others? 🫀

Research led by @mrc-lms.bsky.social finds that visceral fat – the 'invisible fat' around your organs – may be a key culprit.

But for women, fat on the hips & thighs could actually help slow heart #ageing 👇 www.imperial.ac.uk/news/267773/...

New study finds hidden body fat is linked to faster heart ageing | Imperial News | Imperial College London

Excessive amounts of visceral fat — the hidden fat surrounding organs — is linked with faster ageing of the heart, a new study has found.

www.imperial.ac.uk

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Reposted by MRC Laboratory of Medical Sciences

Wiebke Arlt @wiebkearlt.bsky.social · Sep 3

An article in the BMJ just highlighted the free fall in clinician scientist numbers www.bmj.com/content/390/... - a catastrophe in waiting for health! At the @mrc-lms.bsky.social we support next gen clinician scientists in discovery research and experimental medicine
lms.mrc.ac.uk/work-and-stu...

Chain Florey Clinician Scientist Programme

The Chain Florey programmes allow clinicians at all stages of their careers to experience research and flourish in a dual career.

lms.mrc.ac.uk

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MRC Laboratory of Medical Sciences @mrc-lms.bsky.social · Sep 3

Congratulations to @alexisbarr.bsky.social and Jesus Gil who have received funding awards, together totalling around £3M, from @cancerresearchuk.org!

They will lead two exciting projects that could result in discoveries that make a real difference to the lives of people with cancer in the future.

LMS scientists receive funding to boost cancer research

Cancer Research UK has awarded significant funding to researchers at the MRC Laboratory of Medical Sciences (LMS) to lead two exciting new projects that could result in discoveries that make a real di...

lms.mrc.ac.uk

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Reposted by MRC Laboratory of Medical Sciences

Imperial Medicine @imperialmed.bsky.social · Aug 28

"Our research shows that ‘bad’ fat, hidden deep around the organs, accelerates #aging of the heart."

Research led by Prof Declan O’Regan used AI to analyse over 21,000 UK Biobank heart scans, linking hidden visceral fat to #inflammation.🫀

@mrc-lms.bsky.social
ca.news.yahoo.com/hidden-body-...

Hidden body fat is linked to faster heart aging, researchers say

Premature heart aging can leave people at risk for heart failure and life-threatening cardiac events

ca.news.yahoo.com

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Reposted by MRC Laboratory of Medical Sciences

Declan O’Regan @drdeclanoregan.bsky.social · Aug 22

"Hidden" visceral fat around organs accelerates heart aging - but fat on the hips and thighs could be protective in women. Read our paper out now in the European Heart Journal. #whyCMR doi.org/10.1093/eurh...

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MRC Laboratory of Medical Sciences @mrc-lms.bsky.social · Aug 22

Excessive amounts of visceral fat — the hidden fat surrounding organs — is linked with faster ageing of the heart, according to a new study from @drdeclanoregan.bsky.social and his team at the LMS and @imperialcollegeldn.bsky.social.

New study finds hidden body fat is linked to faster heart ageing

Excessive amounts of visceral fat — the hidden fat surrounding organs — is linked with faster ageing of the heart, a new study from the MRC Laboratory of Medical Sciences (LMS) has found.

lms.mrc.ac.uk

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Reposted by MRC Laboratory of Medical Sciences

Sean @seanlzheng.bsky.social · Aug 21

Great opportunity for someone to join our dynamic group @cvgenomics.bsky.social as a research assistant, where we are using genomics and transcriptomics to better understand heart disease. Closing date 27th August for applications!

@mrc-lms.bsky.social
@jamesware.bsky.social

t.co/u68MZ6DDFD

https://lms.mrc.ac.uk/work/vacancies/research-assistant-2/

t.co

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MRC Laboratory of Medical Sciences @mrc-lms.bsky.social · Aug 21

🚀 Exciting Research Assistant opportunity!

Join Dr Melanie Chan’s team at the LMS as a Research Assistant to uncover the genetics of kidney disease using cutting-edge genomics and bioinformatics!

Apply here 👇

Research Assistant - MRC Laboratory of Medical Sciences

Research Assistant to support Dr Melanie Chan

lms.mrc.ac.uk

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MRC Laboratory of Medical Sciences @mrc-lms.bsky.social · Aug 18

🚨 We’re hiring a Research Assistant! Join the Cardiovascular Genomics Precision Medicine Group at the MRC LMS. Work on cutting-edge research into the genetics of inherited heart disease, gain hands-on lab experience, and help drive discoveries that could transform patient care.

Apply here 👇

Research Assistant - MRC Laboratory of Medical Sciences

Research Assistant supporting Dr Zheng.

lms.mrc.ac.uk

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