Lightnews — Scholar-powered news

Reposted by Danielle Grotjahn

Australian Society for Biochemistry and Molecular Biology - 2025 @asbmbaus.bsky.social · 7d

Thank you to all of our plenary speakers for sharing your incredible research with us at #ASBMB2025! @nanigrotjahn.bsky.social @ajknights7.bsky.social Michelle Haber and Randal Halfmann. We have loved having you all in Brisbane and hearing about your labs awesome work! 🦠🧬🧪🧫🔬

5 6

Reposted by Danielle Grotjahn

Guenter Resch @nexperion.net · 15d

Happy to announce "Technical Innovations Using #SerialEM: A Community Meeting", a new format of hybrid meeting David Mastronarde and I are organizing in April 2026. For more info, a preliminary list of speakers, pre-registration etc. visit
www.nexperion.net/semcm2026

22 49

Reposted by Danielle Grotjahn

Dovile Januliene @djanuliene.bsky.social · 21d

What an inspiring few days at the #WEHeraeusSeminar! Great science, lively discussions, and lots of fun with the amazing community of #cryoEM, #StructuralBiology & #Microscopy. Huge thanks to everyone!

Anika Baier @anikabaier.bsky.social · 21d

Big thanks to @arnemoeller.bsky.social , @djanuliene.bsky.social, all speakers, and everyone who made the #WEHeraeusSeminar - Cryo-EM on the Move such an amazing event! It was a blast!
#cryoEM #StructuralBiology #Microscopy

1 1 10

Reposted by Danielle Grotjahn

Dovile Januliene @djanuliene.bsky.social · 22d

We all love colours, especially, when they can be generated automatically! Fantastic talk by Danielle Grotjahn @nanigrotjahn.bsky.social linking method development, structural biology and cell biology! #WEHeraeusSeminar #cryoEM #StructuralBiology #Microscopy @arnemoeller.bsky.social

3 17

Danielle Grotjahn @nanigrotjahn.bsky.social · 26d

Excited to travel to Germany 🇩🇪 for the WE-Heraeus-Seminar: Cryo‐EM on the Move: New Applications and Challenges! ❄️🔬🧊

I look forward to hearing what everyone is cooking up to make cryoEM better 📈 faster 🏃‍♀️ stronger 💪 😎

www.we-heraeus-stiftung.de/veranstaltun...

Wilhelm und Else Heraeus-Stiftung: Main

www.we-heraeus-stiftung.de

1 11

Danielle Grotjahn @nanigrotjahn.bsky.social · Aug 20

To be considered for this session, please include the following in your submission:

🧫 Topic: Advances in Cell Biology Tools and Technologies
🔬 Subtopic: CryoEM/CryoET
🎤 Format: Minisymposium Talk

Abstract deadline: Sept 3
submissions.mirasmart.com/ASCB2025/Spl...

JavaScript Detection

submissions.mirasmart.com

3

Danielle Grotjahn @nanigrotjahn.bsky.social · Aug 20

🚨 #teamtomo!🚨
Did you know there's a dedicated cryoEM/ET Mini-Symposium at the upcoming ASCB/EMBO meeting in Philly (Dec 6–10)??

2 4 10

Danielle Grotjahn @nanigrotjahn.bsky.social · Jul 29

Ending the week on a high note in SLC with a visit to @uofubiochem.bsky.social after an inspiring M&M 2025 meeting!

U of Utah Dept of Biochemistry @uofubiochem.bsky.social · Jul 28

On Thurs July 31st, Dr. Danielle Grotjahn @nanigrotjahn.bsky.social (Scripps) will give a talk entitled "Lessons from mitochondria on thriving under stress." 12pm in HSEB Alumni Hall!

9

Danielle Grotjahn @nanigrotjahn.bsky.social · Jul 11

It was officially released just today, so you’re only a few hours behind 🙂

1 1

Danielle Grotjahn @nanigrotjahn.bsky.social · Jul 11

Thanks to @baradlab.com for the many conversations about segmentation/morphometrics that helped shape this article and @attychang.bsky.social for help with figures.

3

Danielle Grotjahn @nanigrotjahn.bsky.social · Jul 11

I have lots of opinions—but for your sake, I’ve limited them to segmentation in cryo-ET for this article 😉
www.sciencedirect.com/science/arti...

#teamtomo

Segmenting cryo-electron tomography data: Extracting models from cellular landscapes

Cryo-electron tomography provides an unprecedented view of cellular architecture, yet extracting meaningful biological insights remains challenging. S…

www.sciencedirect.com

1 11 37

Reposted by Danielle Grotjahn

Will Wan @williamnwan.bsky.social · Jul 8

Happy to say that my Current Opinion in Structural Biology article came out today. I hope it helps to guide to you in using cryo-ET to make new biological discoveries!

www.sciencedirect.com/science/arti...

A practical look at cryo-electron tomography image processing: Key considerations for new biological discoveries

Cryo-electron tomography (cryo-ET) enables 3D visualization of complex biological environments without the need for purification, thereby preserving t…

www.sciencedirect.com

2 15 49

Danielle Grotjahn @nanigrotjahn.bsky.social · Jul 11

At the risk of shameless self-promotion, I recently wrote a Current Opinion article on segmentation, where I briefly highlight denoising methods in the section “‘Perfecting’ imperfect data is the first step toward automated segmentation.” www.sciencedirect.com/science/arti...

Segmenting cryo-electron tomography data: Extracting models from cellular landscapes

Cryo-electron tomography provides an unprecedented view of cellular architecture, yet extracting meaningful biological insights remains challenging. S…

www.sciencedirect.com

1 3

Reposted by Danielle Grotjahn

Wiseman Lab @wisemanlab.bsky.social · Jun 27

New work from the lab (w/ @preronabora.bsky.social @mashiatzaman.bsky.social @mitomorph.bsky.social @nanigrotjahn.bsky.social) identifying a compound that activates OMA1-DELE1-HRI signaling to induce mitochondrial remodeling in MFN2-deficient cells. Check it out 👇
www.biorxiv.org/content/10.1...

Drug Repurposing Screen Identifies an HRI Activating Compound that Promotes Adaptive Mitochondrial Remodeling in MFN2-deficient Cells

Pathogenic variants in the mitochondrial outer membrane GTPase MFN2 cause the peripheral neuropathy Charcot-Marie-Tooth Type 2A (CMT2A). These mutations disrupt MFN2-dependent regulation of diverse as...

www.biorxiv.org

6 25

Reposted by Danielle Grotjahn

Ardem Patapoutian @ardemp.bskyverified.social · Jun 19

I spoke with Jade Hindmon, host of @kpbssandiego.bsky.social Midday Edition, about the consequences of the current administration’s cuts to science funding. Please share to help spread the word and raise awareness.
www.kpbs.org/podcasts/kpb...

Nobel laureate on how Trump's cuts are hurting science

Neuroscientist, biologist and 2021 Nobel Prize winner Ardem Patapoutian joined Midday Edition to talk about how the Trump administration's effort to cut back on science spending is impacting researche...

www.kpbs.org

2 120 190

Reposted by Danielle Grotjahn

Nina Turner @ninaturner.bsky.social · Jun 15

As we approach the week leading up to Juneteenth, it’s important to recognize the flag and symbols around the day, as well as taking the opportunity to renew the call for lineage-based reparations for not only chattel slavery, but the harms inflicted upon Black Americans post-emancipation.

5 72 220

Danielle Grotjahn @nanigrotjahn.bsky.social · May 10

higher res group pic 🤩

4

Danielle Grotjahn @nanigrotjahn.bsky.social · May 10

Lots of fans and supporters of @mmedina300kv.bsky.social! Grateful for the community that’s cheered her on every step of the way! @hamid13r.bsky.social @callmemich.bsky.social @attychang.bsky.social @daddea.bsky.social @nitishdua.bsky.social @reikawatanabe.bsky.social

1 6

Danielle Grotjahn @nanigrotjahn.bsky.social · May 10

It’s been a big week for the Grotjahn Lab—our very first graduate student, @mmedina300kv.bsky.social, successfully defended her PhD thesis! 🎉 So proud of everything she’s accomplished and grateful for the light she’s brought to our lab from day one ☀️⚡

3 3 27

Danielle Grotjahn @nanigrotjahn.bsky.social · May 9

Tying self-worth to academic success, only to ask years later, "who am I, really?"

Grateful @frezzalab.bsky.social took the time to capture this tension so beautifully in this article.

Christian Frezza @frezzalab.bsky.social · May 9

I'd like to share this short piece on a topic I hope you will find useful. It is the result of a personl journey and many discussions with friends and peers. Let me know your thoughts.

network.febs.org/posts/the-pr...

The Professional Self: The Enemy Inside

network.febs.org

1 8

Danielle Grotjahn @nanigrotjahn.bsky.social · May 1

I also learned a lot from @landerlab.bsky.social about the figures-to-narrative process. I'm loving the rock and roll mechanism 🤘🎸🎶

2

Reposted by Danielle Grotjahn

Michaela Medina @mmedina300kv.bsky.social · May 1

So excited for this work to be out!! Thanks to @attychang.bsky.social, @hamid13r.bsky.social, blue sky less Daniel Fuentes, @nanigrotjahn.bsky.social and @tomo.science!!!

Danielle Grotjahn @nanigrotjahn.bsky.social · May 1

🚨New preprint!🚨 #teamtomo
We expanded Surface Morphometrics to quantify membrane thickness from cryo-ET—revealing local variation across organelles.

Led by the lab’s first grad student, @mmedina300kv.bsky.social (defending Monday! 🍾) w/ @attychang.bsky.social @hamid13r.bsky.social & @tomo.science

bioRxivpreprint @biorxivpreprint.bsky.social · May 1

Surface morphometrics reveals local membrane thickness variation in organellar subcompartments https://www.biorxiv.org/content/10.1101/2025.04.30.651574v1

3 13

Danielle Grotjahn @nanigrotjahn.bsky.social · May 1

Thanks so much! We ❤️ #MemBrain! It is an awesome tool and a key part of our segmentation workflow. The membranes shown here are quantification-mapped surfaces from Surface Morphometrics, downstream of the MemBrain segmentations. I'm grateful for tools that integrate so well across pipelines!

1 1 2

Danielle Grotjahn @nanigrotjahn.bsky.social · May 1

thank you! Please reach out if you need help applying Surface morphometrics to your data--we're happy to help!

1

Danielle Grotjahn @nanigrotjahn.bsky.social · May 1

Grateful to keep collaborating with @tomo.science's new lab as we push the boundaries of what we can measure from cellular ultrastructure. A blue-torial breaking down how we quantify membrane thickness with Surface Morphometrics is coming soon—stay tuned! 👀

7