Lightnews — Scholar-powered news

Nathalie Jurisch-Yaksi @nathaliejuya.bsky.social · 15d

Very special encounter today at Prague museum! It was incredible to see the skeleton of two of the first humanoids Lucy and Selam from 3.2 millions years ago. I highly recommend to anyone visiting Prague! @emreyaksi.bsky.social

The original fossils of human ancestors Lucy & Selam welcome you to the new exhibition People and Their Ancestors - National museum

Exclusively on display from Ethiopia – the land of origin

www.nm.cz

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Nathalie Jurisch-Yaksi @nathaliejuya.bsky.social · 16d

I had a blast visiting @imgprague.bsky.social in Prague. Thanks Sindija Šmite and Martina Huranova for hosting me and giving me the chance to not only share our research but also discuss about Data Management and #FAIR principles at the annual PhD conference. Thanks for your warm welcome.

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Nathalie Jurisch-Yaksi @nathaliejuya.bsky.social · 21d

🍾👏🎉🥳👏🎊🍾🥂🥂

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Reposted by Nathalie Jurisch-Yaksi

Emre Yaksi @emreyaksi.bsky.social · 22d

Check out this exciting study led by Anh-Tuan Trinh from our lab, where we investigated how thalamocortical-like circuits in the zebrafish pallium receive, represent, and integrate sensory information:
🔗 doi.org/10.1101/2025...

Hierarchical processing of sensory information across topographically organized thalamocortical-like circuits in the zebrafish brain

Thalamocortical projections contribute to the spatial organization and functional hierarchies of the mammalian cortex. Primary sensory cortices receive topographically segregated information from firs...

doi.org

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Nathalie Jurisch-Yaksi @nathaliejuya.bsky.social · 28d

And if our tools could benefit your research, do not hesitate to reach out to us 😊

Nathalie Jurisch-Yaksi @nathaliejuya.bsky.social · 28d

Our video is part of a competition initiated by EP Personalized Medicine and to win, we need as many like as possible on the youtube video. Press the like button to get to know more about our work and support her and our project! Thanks for your help!

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Nathalie Jurisch-Yaksi @nathaliejuya.bsky.social · 28d

Learn about our latest glioblastoma project in the lab led by Natalia Kostilek in collaboration with Gopalakrishnan's lab from University Jena and GliomaPerMed!
Natalia is using patient-derived glioblastoma #zebrafish models to understand patient heterogeneity and find cancer therapy.

Glioma-PerMed - Glioma invasion assays as a predictive tool for personalised glioma medicine

YouTube video by European Partnership for Personalised Medicine

www.youtube.com

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Nathalie Jurisch-Yaksi @nathaliejuya.bsky.social · Sep 1

Ok we have a deal…. 🤩🤩🤩

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Nathalie Jurisch-Yaksi @nathaliejuya.bsky.social · Sep 1

This year is unfortunately a bit tight but what about next year. It may involve giving a scientific talk?

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Nathalie Jurisch-Yaksi @nathaliejuya.bsky.social · Sep 1

With pleasure. The other alternative is for you to come and visit us at that time of the year????

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Nathalie Jurisch-Yaksi @nathaliejuya.bsky.social · Sep 1

A typical fall in this part of the world. Luckily we could store a bunch for the winter…

Nathalie Jurisch-Yaksi @nathaliejuya.bsky.social · Aug 30

Hard work pays off! Autumn in Norway 🍄‍🟫🍄🍄‍🟫 @emreyaksi.bsky.social

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Reposted by Nathalie Jurisch-Yaksi

UK Cilia and Centrosome Network @ukcilianetwork.bsky.social · Aug 13

This has always been a fantastic community driven meeting. It is also a rare forum for scientists, patients and clinicians to come together to come up with solutions to solve the biggest challenges facing the cilia community and fill knowledge gaps. All cilia enthusiasts - mark your calendars!

EuroCilia2027 @eurocilia.bsky.social · Aug 11

Have you saved the date for #Cilia2027?
It is going to be in March 2027 at this lake near #Milan. 👇

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Reposted by Nathalie Jurisch-Yaksi

EuroCilia2027 @eurocilia.bsky.social · Aug 11

Have you saved the date for #Cilia2027?
It is going to be in March 2027 at this lake near #Milan. 👇

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Nathalie Jurisch-Yaksi @nathaliejuya.bsky.social · Aug 14

Thanks to all authors, especially first author Halvor Herlyng, and all co-authors @inyoungj88.bsky.social, Ada Ellingsrud, Miroslav Kuchta, and Marie E. Rognes @utropstegn.bsky.social for this exciting journey, and our funding from Norges forskningsråd.

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Nathalie Jurisch-Yaksi @nathaliejuya.bsky.social · Aug 14

🔍 Our surprising finding? While cilia help move larger particles, diffusion plays a dominant role in distributing small proteins. This raises fascinating questions: how effective such a system is for brain signaling—especially in larger brains like in humans, where diffusion might be less efficient.

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Nathalie Jurisch-Yaksi @nathaliejuya.bsky.social · Aug 14

To investigate, we used a multidisciplinary approach combining in silico and in vivo methods in zebrafish embryos, which offer a simplified yet highly informative model of the ventricular system. Check out this photoconversion timelapse from @inyoungj88.bsky.social

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Nathalie Jurisch-Yaksi @nathaliejuya.bsky.social · Aug 14

Previous work—including from our own lab—has shown that CSF movement is regulated by a several biological processes: motile cilia, heart pulsations, body movements, and fluid secretion. Cilia, in particular, are often thought to be key drivers of CSF distribution. But is that really the case?

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Nathalie Jurisch-Yaksi @nathaliejuya.bsky.social · Aug 14

CSF carry many solutes, like metabolites, signaling molecules, waste products and extracellular vesicles. But how exactly do these molecules travel? Are they mixed or dispersed, or do they accumulate in specific regions? Understanding this could unlock new insights into brain function and signaling.

a cartoon sheep is holding a plate in his hands in a kitchen .

ALT: a cartoon sheep is holding a plate in his hands in a kitchen .

media.tenor.com

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Nathalie Jurisch-Yaksi @nathaliejuya.bsky.social · Aug 14

In this study, we combined computational modeling and experimental data to explore how molecules move through the cerebrospinal fluid (CSF)— which flows through the brain’s ventricles like water in rivers and ponds.

a stream of water is flowing through rocks in a forest .

ALT: a stream of water is flowing through rocks in a forest .

media.tenor.com

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Nathalie Jurisch-Yaksi @nathaliejuya.bsky.social · Aug 14

🚩Publication Alert🚩"Advection vs. Diffusion in Brain Ventricular Transport" by Herlyng at al in collaboration with @utropstegn.bsky.social at @simularesearch.bsky.social and Jebsen Centre for Brain Fluid Research is now published in Fluids and Barriers of the CNS! 🧠💧

Advection versus diffusion in brain ventricular transport - Fluids and Barriers of the CNS

Cerebrospinal fluid (CSF) is integral to brain function. CSF provides mechanical support for the brain and helps distribute nutrients, neurotransmitters and metabolites throughout the central nervous ...

doi.org

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Reposted by Nathalie Jurisch-Yaksi

Emre Yaksi @emreyaksi.bsky.social · Aug 5

New publication from our lab is just out! rdcu.be/ezk1U
In brief, we showed that glutamate-driven inhibition in the habenula can alter neural activity and connectivity, leading to amplified sensory responses and defensive behaviors.

Inhibition mediated by group III metabotropic glutamate receptors regulates habenula activity and defensive behaviors

Nature Communications - The role of glutamate-driven inhibition in neural computations and animal behavior is not fully understood. This study reveals that group III metabotropic glutamate...

rdcu.be

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Reposted by Nathalie Jurisch-Yaksi

EuroCilia2027 @eurocilia.bsky.social · Jul 29

Save the date!
March 2027 on beautiful lake Maggiore right outside #Milan, are you ready for #Cilia2027? 🥳
Stay tuned for more info!

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Nathalie Jurisch-Yaksi @nathaliejuya.bsky.social · Jul 14

This is an amazing news! Congrats to the team!!!!

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Nathalie Jurisch-Yaksi @nathaliejuya.bsky.social · Jul 12

Have fun!

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