Loops derived from right heart catheterization (RV pressure via Swan-Ganz) and analyzed with our newly published workflow

🔗 Paper: www.jhltonline.org/article/S105...
🛠️ PV-loop generator: pv-loop-generator.onrender.com

@khodrtello.bsky.social @hemodynamix.bsky.social @zentensivist.bsky.social

Key findings from the PV-loops:
➡️ Marked pressure reduction
➡️ Significant decrease in afterload (Ea)
➡️ RV-PA coupling nearly doubles (0.48 → 0.95)
➡️ Stroke work (area of PV-loop) decreases substantially
➡️ Unstressed volume (V0, intercept of Ees with x-axis) normalizes

💉 Treprostinil s.c. 60 ng/kg/min
💊 Macitentan 10 mg
💊 Tadalafil 40 mg

In this case, triple therapy not only lowers pulmonary pressures but also lets the RV work more efficiently — restoring RV-arterial coupling and reducing energetic strain.

Democratization of PV loops😉 – no conductance catheter needed

Whenever you have questions, feel free to reach out

Thanks, Matt! In principle, the use is quite straightforward. You can simply export CSV or TXT files from your catheterization system and upload them. Calibration can then be done by entering CO or by volumetric data (MRI or echo). We’re currently working on a built-in user guide for the tool.

We introduce a tool that derives RV PV loops from routine right heart cath data.
✅ Simplifies advanced RV analysis with PV Loops
✅ Stroke work & coupling metrics in seconds
✅ Freely available: pv-loop-generator.onrender.com

#PulmonaryHypertension #RVFunction #Hemodynamics
#RightVentricle