Organic Chemistry Frontiers
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Organic Chemistry Frontiers
@orgchemfront.rsc.org
560 followers 930 following 190 posts
An international high impact journal for cutting-edge research from all disciplines of organic chemistry.

Published by @rsc.org 🌐 Website: rsc.li/orgchemfront
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📢 Welcome to issue 24 of OCF, please read the cover article by Esteban Mejía 𝘦𝘵 𝘢𝘭.

𝐉𝐚𝐧𝐮𝐬-𝐭𝐲𝐩𝐞 𝐩𝐡𝐨𝐭𝐨-𝐫𝐞𝐝𝐨𝐱 𝐩𝐫𝐨𝐩𝐞𝐫𝐭𝐢𝐞𝐬 𝐚𝐧𝐝 𝐜𝐚𝐭𝐚𝐥𝐲𝐭𝐢𝐜 𝐚𝐩𝐩𝐥𝐢𝐜𝐚𝐭𝐢𝐨𝐧𝐬 𝐨𝐟 𝟓,𝟏𝟎-𝐝𝐢𝐡𝐲𝐝𝐫𝐨𝐩𝐡𝐞𝐧𝐚𝐳𝐢𝐧𝐞 𝐝𝐞𝐫𝐢𝐯𝐚𝐭𝐢𝐯𝐞𝐬

🔗 doi.org/10.1039/D5QO01348H
December 3, 2025 at 6:14 AM
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🎉Issue 23 of OCF is released now, please check out the cover article：

𝐏𝐝-𝐜𝐚𝐭𝐚𝐥𝐲𝐬𝐞𝐝 𝐟𝐥𝐨𝐰 𝐓𝐬𝐮𝐣𝐢–𝐓𝐫𝐨𝐬𝐭 𝐚𝐥𝐥𝐲𝐥𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐩𝐡𝐞𝐧𝐨𝐥𝐬: 𝐜𝐨𝐧𝐭𝐢𝐧𝐮𝐨𝐮𝐬-𝐟𝐥𝐨𝐰, 𝐞𝐱𝐭𝐫𝐚𝐜𝐭𝐢𝐨𝐧-𝐟𝐫𝐞𝐞 𝐬𝐲𝐧𝐭𝐡𝐞𝐬𝐢𝐬 𝐨𝐟 𝐞𝐬𝐦𝐨𝐥𝐨𝐥 𝐯𝐢𝐚 𝐚𝐥𝐥𝐲𝐥𝐚𝐭𝐢𝐨𝐧, 𝐞𝐩𝐨𝐱𝐢𝐝𝐚𝐭𝐢𝐨𝐧, 𝐚𝐧𝐝 𝐚𝐦𝐢𝐧𝐨𝐥𝐲𝐬𝐢𝐬 by Shū Kobayashi 𝘦𝘵 𝘢𝘭.

🔗 doi.org/10.1039/D5QO01336D
November 19, 2025 at 5:55 AM
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🎉Issue 22 of Organic Chemistry Frontiers has been released! Read the cover article by Mitsuhiro Arisawa 𝘦𝘵 𝘢𝘭

🔗 doi.org/10.1039/D5QO01123J
November 5, 2025 at 8:21 AM
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Issue 21 is online now! Check out our cover article:

𝐒𝐮𝐛-𝐫𝐨𝐨𝐦 𝐭𝐞𝐦𝐩𝐞𝐫𝐚𝐭𝐮𝐫𝐞 𝐭𝐫𝐚𝐧𝐬𝐟𝐞𝐫 𝐡𝐲𝐝𝐫𝐨𝐠𝐞𝐧𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 α,β-𝐮𝐧𝐬𝐚𝐭𝐮𝐫𝐚𝐭𝐞𝐝 𝐤𝐞𝐭𝐨𝐧𝐞𝐬 𝐮𝐬𝐢𝐧𝐠 𝐦𝐞𝐭𝐡𝐚𝐧𝐨𝐥 𝐚𝐬 𝐚 𝐡𝐲𝐝𝐫𝐨𝐠𝐞𝐧 𝐬𝐨𝐮𝐫𝐜𝐞 by Sanjay Pratihar 𝘦𝘵 𝘢𝘭.

🔗 doi.org/10.1039/D5QO01133G
October 22, 2025 at 7:34 AM
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👉OCF is involved in an RSC cross-journal themed collection Celebrating 200 Years of Benzene, guest edited by Ben Feringa
@feringalab.bsky.social & Nazario Martin.

Detailed information could be found here:
🔗 www.rsc.org/publishing/j...
October 14, 2025 at 8:14 AM
orgchemfront.rsc.org
👉Don't miss the outside back cover article of issue 20:

𝐒𝐢𝐭𝐞 𝐬𝐞𝐥𝐞𝐜𝐭𝐢𝐯𝐞 𝐇𝐞𝐜𝐤 𝐚𝐫𝐲𝐥𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐍-𝐯𝐢𝐧𝐲𝐥-𝟕-𝐚𝐳𝐚𝐢𝐧𝐝𝐨𝐥𝐞 𝐞𝐧𝐠𝐢𝐧𝐞𝐞𝐫𝐞𝐝 𝐛𝐲 𝐍-𝐨𝐱𝐢𝐝𝐞 𝐚𝐜𝐭𝐢𝐯𝐚𝐭𝐢𝐨𝐧: 𝐬𝐜𝐨𝐩𝐞 𝐚𝐧𝐝 𝐦𝐞𝐜𝐡𝐚𝐧𝐢𝐬𝐭𝐢𝐜 𝐬𝐭𝐮𝐝𝐢𝐞𝐬

by Parthasarathi Das 𝘦𝘵 𝘢𝘭.
🔗 doi.org/10.1039/D5QO00976F
October 9, 2025 at 6:00 AM
orgchemfront.rsc.org
📢 Issue 20 of OCF is now available! Read the outside front cover article

𝐁𝐲𝐩𝐚𝐬𝐬𝐢𝐧𝐠 𝐭𝐡𝐞 𝐚𝐛𝐧𝐨𝐫𝐦𝐚𝐥 𝐂𝐡𝐢𝐜𝐡𝐢𝐛𝐚𝐛𝐢𝐧 𝐫𝐞𝐚𝐜𝐭𝐢𝐨𝐧 𝐝𝐞𝐚𝐝-𝐞𝐧𝐝 𝐩𝐫𝐨𝐯𝐢𝐝𝐞𝐬 𝐚 𝐛𝐢𝐨𝐦𝐢𝐦𝐞𝐭𝐢𝐜 𝐚𝐜𝐜𝐞𝐬𝐬 𝐭𝐨 𝐩𝐫𝐞-𝐡𝐚𝐨𝐮𝐚𝐦𝐢𝐧𝐞

by Mehdi A. Beniddir, Erwan Poupon 𝘦𝘵 𝘢𝘭.
🔗 doi.org/10.1039/D5QO01111F
October 9, 2025 at 5:58 AM
orgchemfront.rsc.org
We have published a outside back over article, read

𝐄𝐥𝐞𝐜𝐭𝐫𝐨𝐩𝐡𝐢𝐥𝐢𝐜 𝐢𝐧𝐬𝐞𝐫𝐭𝐢𝐨𝐧 𝐚𝐧𝐝 𝐫𝐢𝐧𝐠 𝐠𝐫𝐨𝐰𝐭𝐡 𝐢𝐧 𝟏,𝟐,𝟓-𝐚𝐳𝐚𝐝𝐢𝐛𝐨𝐫𝐨𝐥𝐢𝐝𝐢𝐧𝐞𝐬: 𝐭𝐡𝐞𝐨𝐫𝐞𝐭𝐢𝐜𝐚𝐥 𝐞𝐯𝐢𝐝𝐞𝐧𝐜𝐞 𝐟𝐨𝐫 𝐛𝐨𝐫𝐨𝐧-𝐝𝐫𝐢𝐯𝐞𝐧 𝐞𝐱𝐩𝐚𝐧𝐬𝐢𝐨𝐧

by J. Oscar C. Jiménez-Halla 𝘦𝘵 𝘢𝘭.
🔗 doi.org/10.1039/D5QO...
September 26, 2025 at 8:57 AM
orgchemfront.rsc.org
Don't miss the inside front cover article of issue 19

𝐂𝐨𝐨𝐩𝐞𝐫𝐚𝐭𝐢𝐯𝐞 𝐍-𝐡𝐞𝐭𝐞𝐫𝐨𝐜𝐲𝐜𝐥𝐢𝐜 𝐜𝐚𝐫𝐛𝐞𝐧𝐞/𝐩𝐡𝐨𝐭𝐨𝐜𝐚𝐭𝐚𝐥𝐲𝐬𝐢𝐬: 𝐯𝐢𝐬𝐢𝐛𝐥𝐞-𝐥𝐢𝐠𝐡𝐭-𝐩𝐫𝐨𝐦𝐨𝐭𝐞𝐝 𝐭𝐚𝐧𝐝𝐞𝐦 α-𝐬𝐩³ 𝐂–𝐇 𝐚𝐜𝐭𝐢𝐯𝐚𝐭𝐢𝐨𝐧 𝐚𝐧𝐝 𝐫𝐞𝐝𝐮𝐜𝐭𝐢𝐯𝐞 𝐍-𝐚𝐥𝐤𝐲𝐥𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐭𝐞𝐭𝐫𝐚𝐡𝐲𝐝𝐫𝐨𝐢𝐬𝐨𝐪𝐮𝐢𝐧𝐨𝐥𝐢𝐧𝐞

by C. Uma Maheswari 𝘦𝘵 𝘢𝘭.
🔗 doi.org/10.1039/D5QO...
September 26, 2025 at 8:54 AM
orgchemfront.rsc.org
📢 Issue 19 of Organic Chemistry Frontiers is available! In this issue read the outside front cover article:

𝐓𝐮𝐧𝐚𝐛𝐥𝐞 𝐭𝐡𝐢𝐨𝐟𝐮𝐦𝐚𝐫𝐚𝐭𝐞 𝐬𝐭𝐞𝐫𝐞𝐨𝐬𝐞𝐥𝐞𝐜𝐭𝐢𝐯𝐞 𝐜𝐲𝐜𝐥𝐨𝐚𝐝𝐝𝐢𝐭𝐢𝐨𝐧𝐬 𝐯𝐢𝐚 𝐚𝐦𝐢𝐧𝐨𝐦𝐞𝐟𝐥𝐨𝐪𝐮𝐢𝐧𝐞 𝐜𝐚𝐭𝐚𝐥𝐲𝐬𝐢𝐬

by Rafał Szabla, Rafał Kowalczyk 𝘦𝘵 𝘢𝘭.
🔗 doi.org/10.1039/D5QO...
September 26, 2025 at 8:51 AM
orgchemfront.rsc.org
Back cover of Issue 18 showcases research from Basab Bijayi Dhar 𝘦𝘵 𝘢𝘭.

Oxidative copper-catalyzed synthesis of β-amino ketones from allyl alcohols and anilines

#Free_to_read
🔗 doi.org/10.1039/D5QO...
September 11, 2025 at 10:02 AM
orgchemfront.rsc.org
🔔Issue 18 is available! Please read the cover article:

Exploring the intricacies of inverse hydride shuttle catalysis in azabicyclic scaffold construction with contiguous stereocenters by Vidya Avasare 𝘦𝘵 𝘢𝘭.

#Free_to_read
🔗https://doi.org/10.1039/D5QO00627A
September 11, 2025 at 10:01 AM
orgchemfront.rsc.org
Back cover of Issue 17 showcases research from Antonio Leyva-Pérez 𝘦𝘵 𝘢𝘭.

Countercation- and solvent-controlled selective borohydride hydrogenation of alkenes in diaryl enones

#Free_to_read
🔗 doi.org/10.1039/D5QO...
August 20, 2025 at 8:31 AM
orgchemfront.rsc.org
🔔Issue 17 is available! Please read the cover article:

Metal- and base-free spirocyclization of alkylidene oxindoles via photo- and mechanochemically-generated nitrile ylides and nitrile imines as 1,3-dipoles by Subhabrata Sen 𝘦𝘵 𝘢𝘭.

#Free_to_read
🔗DOI doi.org/10.1039/D5QO...
August 20, 2025 at 8:29 AM
orgchemfront.rsc.org
✨ New paper: Metal- & base-free spirocyclization of alkylidene oxindoles via photo- & mechanochemically generated 1,3-dipoles.

⚡ Efficient 3+2 cycloadditions
⚡ Access to spiro[pyrrolidine-oxindoles] & spiro[indoline-pyrazolones]

doi.org/10.1039/D5QO00851D
#OrganicChemistry
August 18, 2025 at 9:35 AM
orgchemfront.rsc.org
🔔Issue 16 is available!

Explore the latest research and insights in our newest issue — don’t miss it!
August 8, 2025 at 8:41 AM
orgchemfront.rsc.org
🔔Issue 15 is available! Please read the cover article:

Azlactone rings: uniting tradition and innovation in synthesis by Pedro P. de Castro, Giovanni W. Amarante 𝘦𝘵 𝘢𝘭.

#Free_to_read
doi.org/10.1039/D5QO...
July 23, 2025 at 4:45 PM
orgchemfront.rsc.org
📢 Welcome to the latest issue of Organic Chemistry Frontiers, in this issue read the cover article:

👉 C–H bond halogenation: unlocking regiodivergence and enhancing selectivity through directing group strategies by Kamaldeep Paul et al.

🔗 doi.org/10.1039/D5QO00372E
July 9, 2025 at 4:36 AM
orgchemfront.rsc.org
Back cover of Issue 13 showcases research from Dmytro M. Volochnyuk, Serhiy V. Ryabukhin 𝘦𝘵 𝘢𝘭.

Oxetane as a part of modern medicinal chemistry toolbox: the advanced synthesis of 3,3-disubstituted building blocks

#Free_to_read
🔗 doi.org/10.1039/D5QO...
June 26, 2025 at 6:40 AM
orgchemfront.rsc.org
Inside cover of Issue 13 presents

"Direct Suzuki–Miyaura cross-coupling of C(sp²)–B(dan) bonds: designed in pursuit of usability" by Teruhisa Tsuchimoto 𝘦𝘵 𝘢𝘭.

#Free_to_read
🔗 doi.org/10.1039/D5QO...
June 26, 2025 at 6:34 AM
orgchemfront.rsc.org
🔔Issue 13 is available! Please read the cover article:

"Garynthone A–I, PPAPs with diverse skeletons isolated from 𝘎𝘢𝘳𝘤𝘪𝘯𝘪𝘢 𝘺𝘶𝘯𝘯𝘢𝘯𝘦𝘯𝘴𝘪𝘴 and their immunosuppressive activity" by Jingming Jia, Anhua Wang 𝘦𝘵 𝘢𝘭.

#Free_to_read
🔗https://doi.org/10.1039/D5QO00414D
June 26, 2025 at 6:33 AM
orgchemfront.rsc.org
📢Be sure to check out the inside cover and back cover in issue 11 of Organic Chemistry Frontiers!

👉Read the full research here:
doi.org/10.1039/D5QO...
doi.org/10.1039/D5QO...

#OCF_cover #Chemsky
June 3, 2025 at 3:41 AM
orgchemfront.rsc.org
📢On the cove of Issue 11:
#Supramolecular catalysis in the dearomative Michael addition involving nitro-group-activated benzofurans

by Anna Skrzyńska, Łukasz Albrecht et al. from Lodz University of Technology
doi.org/10.1039/D5QO...
June 3, 2025 at 3:38 AM
orgchemfront.rsc.org
📢Don't miss our CCS-RSC Young Chemist webinar! Meet with Dr. Agnieszka Nowak-Król, Early career advisory board member of Organic Chemistry Frontiers, and other young scientists!
⏰Time: 7:00 am (UK time)
📅Date: May 30, 2025
👉Register the webinar here: rsc.zoom.us/webinar/regi...

@rsc.org #OCF
May 23, 2025 at 9:07 AM
orgchemfront.rsc.org
📢Don't miss the inside #cover of our latest issue and the #research behind it!
👉Unraveling the α-effect in α-fluorinated carbanionic nucleophiles: origins and synthetic implications
by Jimin Yang and Xiao-Song Xue
#Chemsky #OCF_cover
doi.org/10.1039/D5QO...
May 8, 2025 at 10:10 AM