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Reposted by Paraskevi Kritsiligkou

EMBO @embo.org · 2d

Want to apply for an EMBO Postdoctoral #Fellowship? 🧪

Here are tips from the EMBO Fellowship Committee:
www.youtube.com/watch?v=xY7c...
#LifeSciences #grant #funding

How to apply for an EMBO Postdoctoral Fellowship: Tips from the Committee

YouTube video by EMBO - excellence in life sciences

www.youtube.com

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qiangguo.bsky.social @qiangguo.bsky.social · 4d

What's the role of stress granules in translation? Here we provide a clue: we characterized the distribution of ribosomal complexes within SGs and reproduced this landscape with a phase-field model, pointing to a new regulatory mechanism. #TEAMTOMO www.science.org/doi/10.1126/...

Translation landscape of stress granules

Cryo–electron tomography visualizes stress granules in situ, revealing their spatial interplay with translation machinery.

www.science.org

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John Ngo @johntngo.bsky.social · 16d

🚀 Our new paper is out @natmethods.nature.com!

Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells.

🔗 www.nature.com/articles/s41...
🧬 www.addgene.org/John_Ngo/

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James Nathan @jamesnathanlab.bsky.social · 20d

Happy to share latest work from the lab. Led by talented first author @awmartinelli.bsky.social. Mapping the genetic landscape of iron metabolism uncovers the SETD2 methyltransferase as a modulator of iron flux | Science Advances www.science.org/doi/10.1126/... Congratulations to all the team.

Mapping the genetic landscape of iron metabolism uncovers the SETD2 methyltransferase as a modulator of iron flux

Genetic screens using endogenous reporters map key modulators of cellular iron, including the transcriptional regulator SETD2.

www.science.org

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Reposted by Paraskevi Kritsiligkou

Milo B. Fasken, Ph.D. @milofasken.bsky.social · 18d

www.cell.com/molecular-ce...

Rapid remodeling of NTP levels enables immediate translational adaptation to energy stress in yeast

Bexley et al. report that rapid metabolic shifts mediate immediate, protective changes in RNA metabolism following energy depletion. In yeast, protein production is regulated by tuning enzymatic const...

www.cell.com

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Paraskevi Kritsiligkou @parikki.bsky.social · Sep 4

Metabolic dysfunction-associated steatohepatitis reduces hepatic H2S-producing enzymes altering persulfidome composition

Metabolic dysfunction–associated steatohepatitis (MASH) is a progressive disease driven by obesity-related hepatic inflammation and oxidative stress. …

www.sciencedirect.com

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Dr Zeinab Rekad 🔬🧬🧪 @zeinabrekad.bsky.social · Jul 27

#RNAsky
💜💜💜💜💜💜💜

@NicoliLab @nicolilab.bsky.social · Jul 26

RNA can control cell migration by acting at focal adhesions www.lifescienceeditors.com/2025/06/24/r...

RNA can control cell migration by acting at focal adhesions - Scientific editing and writing experts - Life Science Editors

Scientific editing and writing experts for manuscripts and grants

www.lifescienceeditors.com

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Paraskevi Kritsiligkou @parikki.bsky.social · Jul 25

It was a super cool talk 🎉

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Paraskevi Kritsiligkou @parikki.bsky.social · Jul 25

On my way back from a truly brilliant yeast meeting! With more than 500 participants, so much cool science and loads of fruitful discussions, this week was remarkable! #yeast2025

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Paraskevi Kritsiligkou @parikki.bsky.social · Jul 21

I am in Paris this week for #yeast2025!

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James Nathan @jamesnathanlab.bsky.social · Jul 15

Delighted to share our latest work on ABHD11 as a novel deglutarylating enzyme, and its role in T cell metabolism @natchembio.nature.com rdcu.be/ewiYZ. Many congratulations to co-first authors Guine Grice, Eleanor Minogue and @hudsonwilco.bsky.social! Great team effort with Randall Johnson's lab.

Lipoyl deglutarylation by ABHD11 regulates mitochondrial and T cell metabolism

Nature Chemical Biology - Glutarate rewires cell metabolism through conjugation to proteins or fatty acids, but how glutarylation is regulated is unclear. ABHD11 was identified as a...

rdcu.be

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Paraskevi Kritsiligkou @parikki.bsky.social · Jul 15

Congratulations! 🎉

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Paraskevi Kritsiligkou @parikki.bsky.social · Jul 13

www.science.org/doi/10.1126/...

ROS transfer at peroxisome-mitochondria contact regulates mitochondrial redox

Maintenance of mitochondrial redox homeostasis is of fundamental importance to cellular health. Mitochondria harbor a host of intrinsic antioxidant defenses, but the contribution of extrinsic, nonmito...

www.science.org

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Alexey Amunts @amunts.bsky.social · Jul 7

Our new preprint: how photoprotection is spatially coordinated with energy metabolism. Photosystem I is major source of radicals. We report EM structure of PSI in complex with superoxide dismutase SOD: direct link between energy conversion & oxidative stress defence
www.biorxiv.org/content/10.1...

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Helena Cocheme @cochemelab.bsky.social · Jun 27

🎉Excited to share our latest paper, published in Nature Communications!🎉

"Enhancing autophagy by redox regulation extends lifespan in Drosophila"

#redox #metabolism #ageing #Drosophila

@natcomms.nature.com @mrc-lms.bsky.social

doi.org/10.1038/s414...

Enhancing autophagy by redox regulation extends lifespan in Drosophila - Nature Communications

Redox signalling is emerging as an important regulator of metabolism and physiology, which is dysregulated in ageing and disease. Here, the authors show that redox regulation of a key redox sensitive ...

doi.org

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Robert E. Campbell @campbell-lab.bsky.social · Apr 19

New tools! GreenPy and ApplePy are fluorescent biosensors for pyruvate with huge responses (20–40x in vitro) and a range of affinities (10s of μM to mM). These should be game changers for imaging of metabolism! Great work by Shosei Imai @sikmys.bsky.social and team 👏. www.biorxiv.org/content/10.1...

High-performance genetically-encoded green and red fluorescent biosensors for pyruvate

Pyruvate is the end-product of glycolysis and a central metabolite involved in many biochemical pathways. However, a lack of high-performance (i.e., Δ F / F > 10) single fluorescent protein (FP)-base...

www.biorxiv.org

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Marko Kaksonen @kaksonen.bsky.social · Jun 24

How do cells switch on the actin assembly at endocytic sites? How can this on-switch evolve? Check out our new preprint!
www.biorxiv.org/content/10.1...

Localization of WDS proteins and fimbrin in three fungal species.

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Will Ratcliff @wcratcliff.bsky.social · Jun 24

1/27 We have a new paper out! Turns out that snowflake yeast have been hiding a secret from us - they've evolved a (very!) crude circulatory system. Not with blood vessels or a heart, but through spontaneous fluid flows powered by their metabolism. 🧪🔬

www.science.org/doi/full/10....

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Guillaume Jacquemet @guijacquemet.bsky.social · Jun 23

Are you looking for a postdoc?
I will be looking for 2-4 people after the summer to join the lab !!
Do not hesitate to reach out and disseminate !!

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Faculty of Health and Life Sciences @livunihls.bsky.social · Jun 20

Congratulations to Dr Aphrodite Vasilaki and Dr Paraskevi Kritsiligkou @parikki.bsky.social who won the Leopold Flohé Redox Pioneer Young Investigator Award and Catherine Pasquier Award respectively at the 2025 Society for Free Radical Research International meeting
▶️ bit.ly/4ebZ9XN

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Paraskevi Kritsiligkou @parikki.bsky.social · Jun 18

Spent the day listening to some amazing talks from first and second year PhD students in our Biochemistry, Cell and Systems Biology Department! I loved how confident and knowledgeable our students are! Can’t wait for my students to give their talks next year 🥹

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Paraskevi Kritsiligkou @parikki.bsky.social · Jun 8

Thanks Ian! Glad you made it to the talk 🙂

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Paraskevi Kritsiligkou @parikki.bsky.social · Jun 7

I am extremely honoured to have received the 2025 Catherine Pasquier Award from SFRR-E in recognition for Extraordinary Scientific Achievements and Great Future Promise! 🥹 Inspired to follow so many past awardees that are now leaders in the field. Truly thankful for the support. ❤️

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Paraskevi Kritsiligkou @parikki.bsky.social · Jun 7

Had a great time at the SFRR-I meeting! I listened to some exciting new science, spent time with my friends that live far away and met my fellow @sfrre-ecr.bsky.social in person!❤️ We successfully organised networking events and a sunrise seminar and it is clear we are building a great community 🎉

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Avilien Dard @avdar66.bsky.social · Jun 6

Outstanding talk by @parikki.bsky.social , recipient of the CATHERINE PASQUIER AWARD LECTURE at SFFR-I Biennial Meeting in Galway @uniofgalway.bsky.social.

Are ROS generated in nanodomains / condensates in cells?

Want to know more, please read her paper
lnkd.in/dq_6Rnaw

@sfrre-ecr.bsky.social

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