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Reposted by Patricia Bernal

Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 1d

Université Grenoble Alpes opens a full professorship in microbiology in 2026. The selected candidate will develop their research program on quantitative approaches in microbiology in the Laboratoire Interdisciplinaire de Physique. More info: liphy.univ-grenoble-alpes.fr/en/join-us/r...

Professorship (tenure) in 'Quantitative approaches in microbiology' (CNU Sections 64/65) | LIPhy - Université Grenoble Alpes

liphy.univ-grenoble-alpes.fr

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Reposted by Patricia Bernal

labnikel.bsky.social @labnikel.bsky.social · 6h

🚀 Thrilled to share our new Nature Communications article:
“A blueprint for designing the next-generation of synthetic C1 microbes”
We propose a framework to unlock sustainable, carbon-efficient biomanufacturing using non-canonical hosts.
🔗 www.nature.com/articles/s41... A short 🧵1/4

A blueprint for designing the next-generation of synthetic C1 microbes - Nature Communications

Synthetic one-carbon assimilation could contribute to a more sustainable and circular carbon economy, but much work in this field has focused on model microorganisms. Here the authors provide their perspective on the potential value of non-model microbes, and how that potential could be realised.

www.nature.com

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Reposted by Patricia Bernal

Patricia Bernal @pbernalt6ss.bsky.social · 1d

Our paper, describing how the T6SSs of P. putida shape the tomato rhizosphere, is now in its final format in @isme-microbes.bsky.social ISME Communications. If you'd like to learn more, here is a thread (1/11) or read the Article doi.org/10.1093/isme....

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Patricia Bernal @pbernalt6ss.bsky.social · 1d

Our research places the T6SS as a critical factor driving the evolution of complex polymicrobial communities within the plant rhizosphere, providing valuable insights for agricultural applications involving beneficial microbes and plant health management strategies. (11/11)

Validate User

doi.org

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Patricia Bernal @pbernalt6ss.bsky.social · 1d

In conclusion, we have shown that the T6SSs are essential for competitive rhizosphere colonisation. The wildtype P. putida strain significantly alters the bacterial community structure compared to T6SS mutants. (10/11)

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Patricia Bernal @pbernalt6ss.bsky.social · 1d

The K1-T6SS specifically affects taxa such as Rhizobiaceae while the K2/K3-T6SSs exclusively affect other groups like Azospirillaceae.
The systems impact a wide phylogenetic range, modulating the abundance of both Gram-positive and Gram-negative bacteria in the rhizosphere. (9/11)

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Patricia Bernal @pbernalt6ss.bsky.social · 1d

The presence of wildtype P. putida strain significantly alters the community structure (beta-diversity) of the resident microbial community when compared to T6SS mutants. Our analysis reveals that the different T6SS clusters show specificity, demonstrating a flexible competitive strategy. (8/11)

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Patricia Bernal @pbernalt6ss.bsky.social · 1d

This substantial decrease underscores the critical role of the T6SSs in persistence within this highly competitive environment, enabling P. putida to successfully establish and outcompete other microbial inhabitants. (7/11)

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Patricia Bernal @pbernalt6ss.bsky.social · 1d

We found that these secretion systems are key for effective rhizosphere colonisation. When tomato plants were inoculated with T6SS-deficient mutant strains, there was a significant reduction in bacterial recovery from the rhizosphere compared to the wildtype strain. (6/11)

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Patricia Bernal @pbernalt6ss.bsky.social · 1d

We demonstrate for the first time the functionality of the K2 and/or K3-T6SS clusters. Silent against standard lab strains, they became functional in vitro against plant pathogens and in vivo within the rhizosphere microbiota, suggesting an adaptive response to competitive pressure.(5/11)

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Patricia Bernal @pbernalt6ss.bsky.social · 1d

P. putida KT2440 is equipped with three T6SS clusters: K1, K2, and K3. Previously, only the K1-T6SS was known to be active under laboratory conditions, where it kills severe plant pathogens such as P. syringae and X. campestris. (4/11)

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Patricia Bernal @pbernalt6ss.bsky.social · 1d

Here, we focused on the rhizosphere, the dense, complex microbial community associated with plant roots. While many plant-associated bacteria contain T6SSs, their overall influence on shaping the rhizosphere microbiota remained limited. (3/11)

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Patricia Bernal @pbernalt6ss.bsky.social · 1d

The T6SSs are contractile nanomachines used by Gram-negative bacteria for contact-dependent elimination of competitors through the delivery of toxic effectors. They are considered influential mechanisms driving the evolution of complex polymicrobial communities, like the gut microbiota. (2/11)

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Patricia Bernal @pbernalt6ss.bsky.social · 1d

Our paper, describing how the T6SSs of P. putida shape the tomato rhizosphere, is now in its final format in @isme-microbes.bsky.social ISME Communications. If you'd like to learn more, here is a thread (1/11) or read the Article doi.org/10.1093/isme....

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Reposted by Patricia Bernal

Gunnar N. Schroeder @gunnarns.bsky.social · 2d

SAVE THE DATE!

The 2026 UK CellularMicrobiologyNetwork meeting will be held 22nd - 23rd of June at @wwiem-qub.bsky.social in Belfast.

Researchers from the UK and beyond are invited to share exciting work on the mechanisms of host-pathogen interactions.

Follow us to stay tuned! www.ukcellmicro.org

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Reposted by Patricia Bernal

Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 3d

Off to @caltechlcssp.bsky.social to follow up the conversation started past Feb in Asilomar on *Biotech Beyond Conventional Containment*. Time to rethink the (now banned) release of Lab-trained microorganisms for extensive environmental remediation in view of new genet technols & urgent global needs

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Reposted by Patricia Bernal

Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · 8d

Come and work with me and @ariannebabina.bsky.social on #Streptomyces evolution and antibiotic production

Origins of a tangled bank: Adaptation and evolution in antibiotic-producing Streptomyces

www.gla.ac.uk/postgraduate...

please repost

University of Glasgow - Postgraduate study - Centres for Doctoral Training - NorthWest Biosciences - Our Projects - Underpinning Bioscience - Paul A Hoskisson

www.gla.ac.uk

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Reposted by Patricia Bernal

Tracy Palmer @proftracypalmer.bsky.social · 3d

Check it out! A proper team effort from past and present group members and a great collaboration with @sergemostowylab.bsky.social

bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 3d

The Staphylococcus aureus LXG-domain toxins EsxX and SAR0287 do not promote virulence in a zebrafish larval infection model https://www.biorxiv.org/content/10.1101/2025.10.04.680436v1

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Patricia Bernal @pbernalt6ss.bsky.social · 3d

Secretion Days was a great meeting! Congratulations to the organisers and speakers, you were fantastic!!! Special kudos for the outstanding keynote speaker @archaellum.bsky.social I fell in love with archaea ❤️ and I am super excited to realise there is still so much to be discovered and be learnt

Julien GIRAUD @juliengiraud.bsky.social · 4d

Amazing science at the 2nd edition of the Secretion Days in Marseille 🌞 ! Huge thanks to all participants and to @archaellum.bsky.social for an outstanding opening talk. Looking forward to the next edition!

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Patricia Bernal @pbernalt6ss.bsky.social · 3d

It was great!! Congratulations everyone 👏 👏👏

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Reposted by Patricia Bernal

Sonja-Verena Albers @archaellum.bsky.social · 6d

Look at this nice cover: beautiful archaella, image made by @sshamphavi.bsky.social !

Thanks also to Marta Rodeiguez for keeping the EM im shape in @ottlab.bsky.social lab!

At @biologyunifreiburg.bsky.social at @uni-freiburg.de @sfb1381.bsky.social @cibss.bsky.social

Nature Microbiology @natmicrobiol.nature.com · 6d

Some keen Observations in Our October issue!

🦠 Cancer microbiome
🌊 Marine microbes in warming oceans
🌐 broad-range phages
🧬 genetically minimised Salmonella
🔧 Viral infection mechanisms
🧪 Oxaloacetate antiviral defence

and more, here: www.nature.com/nmicrobiol/v...

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Reposted by Patricia Bernal

Sonja-Verena Albers @archaellum.bsky.social · Feb 3

Would you expect that Bacteria use an archaellum for swimming? We didn't, but we found that some Chloroflexota do! Find the story here: www.biorxiv.org/content/10.1...

A little thread below 1/n

Horizontal gene transfer of the functional archaellum machinery to Bacteria

Motility in Archaea is driven by a nanomachinery called the archaellum. So far, archaella have been exclusively described for the archaeal domain; however, a recent study reported the presence of arch...

www.biorxiv.org

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Reposted by Patricia Bernal

IBVF @ibvf-sevilla.bsky.social · 6d

Three innovative research projects from the IBVF (CSIC–US) will receive over €500,000 in funding from the Andalusian Regional Government @eegutierrez.bsky.social @angelesaroca.bsky.social @dbvybm.bsky.social @unisevilla.bsky.social @csicandalextrem.bsky.social

More info in our web: l1nq.com/juASe

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Reposted by Patricia Bernal

fillouxlab.bsky.social @fillouxlab.bsky.social · 5d

Nice to see Genevieve @lcbofficiel.bsky.social and Patricia @pbernalt6ss.bsky.social meeting in Marseille to exchange about protein secretion

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Reposted by Patricia Bernal

Zamin Iqbal @zaminiqbal.bsky.social · 12d

Delighted to see our paper studying the evolution of plasmids over the last 100 years, now out! Years of work by Adrian Cazares, also Nick Thomson @sangerinstitute.bsky.social - this version much improved over the preprint. Final version should be open access, apols.
Thread 1/n

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