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PlasmidsNG

@plasmidsng.bsky.social

270 followers 530 following 24 posts

Rapid turnaround, full length plasmid sequencing - £10 a plasmid. Powered by ONT's V14 chemistry & R10.4.1 flow cell Based in Birmingham, England plasmidsng.com

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PlasmidsNG @plasmidsng.bsky.social · 7d

🧬OTD in 1952 Joshua Lederberg proposed the term "plasmid" for extrachromosomal hereditary genetic elements in bacteria 🦠
These tiny DNA molecules play a BIG role in #MolecularBiology, biotechnology & #MicrobialGenomics 🧫

Check out the original paper: doi.org/10.1152/phys...
#Plasmid #MicroSky 🧪👨‍🔬📜

Cell Genetics and Hereditary Symbiosis | Physiological Reviews | American Physiological Society

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PlasmidsNG @plasmidsng.bsky.social · Jun 6

You start explaining:
✔️ Cooked food should be cooled ❄️ below 4°C within 6 hours
✔️ Store leftovers in the fridge
✔️ Always check the fridge temp 🌡️

But before you finish…
😵 They rush to the bathroom 🚽🤮
🕵️‍♂️ You swipe the rice and head to the lab!

PlasmidsNG @plasmidsng.bsky.social · Jun 6

🚑 Call an ambulance

PlasmidsNG @plasmidsng.bsky.social · Jun 6

💊 Offer indigestion tablets

PlasmidsNG @plasmidsng.bsky.social · Jun 6

😴 Recommend they go home

PlasmidsNG @plasmidsng.bsky.social · Jun 6

🤓 Give food storage advice

Reposted by PlasmidsNG

Aisling Brady @aislingbrady.bsky.social · Mar 31

Look what I found! #Microbio25 @microbesng.bsky.social @plasmidsng.bsky.social

PlasmidsNG @plasmidsng.bsky.social · Feb 27

If need WHOLE PLASMID sequencing & you are in Norwich look no further!

It's £10 per plasmid (ex VAT), we are a UK company & there's FREE shipping from our dropbox in JIC reception

We have cool posters too 🤩

@johninnescentre.bsky.social
@norwichmicro.bsky.social #CMINorwich25
#PlasmidSequencing

Ainsley Beaton @ainsley-beaton.bsky.social · Feb 27

Wonderfully artistic advertising from @microbesng.bsky.social. They are already my favourite sticker maker and now we may need to add posters and plasmid sequencing to that

PlasmidsNG @plasmidsng.bsky.social · Feb 20

Looking for a UK company to validate your plasmid?

Our @nanoporetech.com based WHOLE plasmid sequencing service costs £10, just send us a mini-prep 🧬

If you're in Manchester you can get free shipping too 📦

Chat to Carla & Olivija in AV Hill reception Feb 25th, 11-3pm— they're bringing 🧁
#MicroSky

Reposted by PlasmidsNG

Helen McNeil @helenmcneil.bsky.social · Dec 13

I 💙 finding out what our customers do with the data that @microbesng.bsky.social send out!

@meina.bsky.social et al have named 28 actinomycetes after amazing #WomenInScience 👩‍🔬

@leibniz-dsmz.bsky.social are doing a post about each one & they're well worth a read! #MicrobialGenomics #MicroSky #IDsky

Leibniz Institute DSMZ @leibniz-dsmz.bsky.social · Nov 27

DSMZ researchers characterized and named 28 actinomycetes with inhibiting effects against other microbes. Honouring the impact of female scientists, they named the newly described bacteria exclusively after #womeninscience.
👉 tinyurl.com/3uhs8ypc

#biodiversity #antibiotics #microbes
📷 DSMZ

New antibiotic producers described: Old DSMZ treasures with new potential

Researchers name newly described bacteria exclusively after female scientists

Reposted by PlasmidsNG

Tracy Palmer @proftracypalmer.bsky.social · Dec 3

Is this not the finest lab crafted Christmas tree decoration you’ve ever seen? Courtesy of Amy Tooke!

A reindeer crafted from epoendorf tubes and pipette tips

A reindeer crafted from eppendorf tubes and pipette tips

Reposted by PlasmidsNG

PlasmidsNG @plasmidsng.bsky.social · Jun 10

Want a quick, easy & FREE way to post samples to us for sequencing?!? 📦

Look no further, we are rolling out DROPBOXES 🎉

Visit microbesng.com/dropbox to find the nearest box!

Instructions are on the lid, fill in the form & we’ll take care of the rest!

#MicroSky

youtube.com/shorts/WMnjN...

We have DROPBOXES, post your samples for FREE

Want a quick, easy & FREE way to post your samples to us for sequencing?!? 📦Look no further, we are rolling out DROPBOXES 🎉Visit http://microbesng.com/drop...

PlasmidsNG @plasmidsng.bsky.social · Jul 16

Find out more about the inner workings of our
oxford nanopore based whole plasmid sequencing service.

Includes a prime example of why you should always validate your plasmids - even if they're commercial vectors!

linkedin.com/pulse/high-q...

#PlasmidSequencing #ProductDevelopment

High Quality Plasmid Sequencing

Can you believe it’s been more than a year since we launched our plasmid sequencing service!? PlasmidSeq offers rapid turnaround, full length plasmid sequencing at an incredible price of just £10 per ...

PlasmidsNG @plasmidsng.bsky.social · Jun 11

Super cool research 👏

If you're using Reporter Assays check the plasmid is correct before starting 👉 plasmidsng.com

Send a miniprep & for £10 get the WHOLE PLASMID sequence + interactive map, data delivery 1-5 days

Want free delivery too 👉
microbesng.com/documents/dr...
t.co/iQ6P1dF294 #Microsky

Development of an inhibitor of the mutagenic SOS response that suppresses the evolution of quinolone antibiotic resistance

Antimicrobial resistance (AMR) is a growing threat to health globally, with the potential to render numerous medical procedures so dangerous as to be impractical. There is therefore an urgent need for...

PlasmidsNG @plasmidsng.bsky.social · Jun 10

Want a quick, easy & FREE way to post samples to us for sequencing?!? 📦

Look no further, we are rolling out DROPBOXES 🎉

Visit microbesng.com/dropbox to find the nearest box!

Instructions are on the lid, fill in the form & we’ll take care of the rest!

#MicroSky

youtube.com/shorts/WMnjN...

We have DROPBOXES, post your samples for FREE

Want a quick, easy & FREE way to post your samples to us for sequencing?!? 📦Look no further, we are rolling out DROPBOXES 🎉Visit http://microbesng.com/drop...

Reposted by PlasmidsNG

MicrobesNG @microbesng.bsky.social · Jun 3

@drrebeccajhall.bsky.social presented some really cool work on transcriptional responses to MDR plasmid acquisition in E.coli at our Oxford Pop Up event #MNGPopUp @magdalenoxford.bsky.social

📽️ Watch the recording here & please share 👇 youtu.be/tQWLyk7q3Iw

@alanmcn1.bsky.social
@IMIBirmingham

Rebecca Hall | MDR plasmids commonly reprogramme expression of metabolic genes in E.coli

Multidrug resistant Escherichia coli is a leading cause of global mortality. Transfer of plasmids carrying genes encoding beta-lactamases, carbapenamases, an...

Reposted by PlasmidsNG

Helen McNeil @helenmcneil.bsky.social · Apr 29

10 years of plasmid finder 🎉🥰🤩

Loved hearing from Alessandra Carattoli!

#ESCMIDGlobal2024 #ECCMID2024 #plasmids

PlasmidsNG @plasmidsng.bsky.social · Apr 29

Great talk from Alessandra Carattoli on plasmid typing,

There are now over 60,000 available plasmid sequences 🎉

#ESCMIDGlobal2024 #ECCMID2024 #plasmids

PlasmidsNG @plasmidsng.bsky.social · Apr 29

It's getting busy in hall I, ready for “Decoding plasmids in diagnostics and infection control”

#ESCMIDGlobal2024 #ECCMID2024 #plasmids

PlasmidsNG @plasmidsng.bsky.social · Apr 23

🌟 Dive into the fascinating world of plasmid evolution with Will Matlock's brilliant talk from our Oxford Pop Up event, now on YouTube 👉
'Gene essentiality shapes plasmid GC-content' youtu.be/snMchJCJQ5U

@wtmatlock.bsky.social

#ECR #MicrobialGenomics #MNGPopUp #Plasmids

William Matlock | Gene essentiality shapes plasmid GC-content

Plasmids are extrachromosomal replicons. When taken as a whole, plasmids are typically AT-rich compared to the host chromosome. However, the GC-content of in...

Reposted by PlasmidsNG

MicrobesNG @microbesng.bsky.social · Apr 3

Try our new Long-Read Sequencing service for improved de novo bacterial genome assemblies 🧬

Get 50X coverage for £85, with DNA extraction & bioinformatics included! 💰🦠🔍

Powered by @nanopore's latest technology 🚀
microbesng.com/request-quote/
#LongReadSequencing#MicrobialGenomics

PlasmidsNG @plasmidsng.bsky.social · Mar 26

Attention Birmingham! Easter changes to our dropbox collections (Biosciences & IBR stores)

📦 Last collection 27th Mar
❌ NO COLLECTION 3rd Apr
🔄 Pick up resumes 10th Apr

EGG-citing changes coming soon! 🐣

Whole #Plasmid sequencing £10 plasmidsng.com

Want a dropbox microbesng.com/documents/dr...

PlasmidsNG @plasmidsng.bsky.social · Mar 21

Beautiful paper we saw shared on the other place!

"Table 1 has a straight-up list of golden gate overhangs that work well and play nice with each other, up to a 30-piece assembly. No more choosing four random bases and hoping".

pubs.acs.org/doi/10.1021/...

Comprehensive Profiling of Four Base Overhang Ligation Fidelity by T4 DNA Ligase and Application to DNA Assembly

Synthetic biology relies on the manufacture of large and complex DNA constructs from libraries of genetic parts. Golden Gate and other Type IIS restriction enzyme-dependent DNA assembly methods enable...

Reposted by PlasmidsNG

MicrobesNG @microbesng.bsky.social · Mar 18

Dot's prize winning flash talk, from our #Oxford Pop Up event is now available! 🥇📽️

It's a fabulous talk so please like and share! 😍

'Risk factors for plasmid-mediated hospital outbreaks of CPE' by Dorottya Nagy from the Modernising Medical Microbiology group
youtu.be/TQomyKoarbk
#MNGPopUp #AMR

Dorottya Nagy | Risk factors for plasmid-mediated hospital outbreaks of CPE

BackgroundCarbapenemase-producing Enterobacterales (CPE) are critical priority pathogens, epitomising the antimicrobial resistance (AMR) pandemic. Epidemiolo...

Reposted by PlasmidsNG

MicrobesNG @microbesng.bsky.social · Mar 11

Our #microbiology stickers went down a storm at Pop Up Oxford last week 😍🦠 #Stickers #Science #shiny

If anyone is still playing guess the microbe, 🤔 the answers are here!

Got to love some lab swag!

#MNGPopUp #MicrobialGenomics #ECR