Patrick Steinmetz
@prhsteinmetz.bsky.social
1.4K followers 580 following 35 posts
Group leader at Michael Sars Centre, University of Bergen. How food regulates growth in a sea anemone. Also: Wildlife & landscape photography. Hiking. Fishing. Consciousness. Meditation. #EvoDevo #Development #EvoPhysio https://orcid.org/0000-0002-3705-277
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prhsteinmetz.bsky.social
Excited to have been part of this Special Issue in Development!
Read about the cellular basis of sea anemone growth & shrinkage: t.co/jgrEBb98Kl
@msarscentre.bsky.social
Sea anemones dramatically shrink over 200 days of starvation, and return to a similar size within 2 weeks of refeeding.
Reposted by Patrick Steinmetz
jamesbriscoe.bsky.social
Very sad news, John Gurdon has died.

A developmental biologist's developmental biologist, Nobel prize winner

His work is the foundation of much of today's dev & stem cell bio.

An inspiration to many, including me. Always asking questions & wanting the answers

www.magd.cam.ac.uk/news/profess...
Professor Sir John Gurdon FRS (1933-2025) | Magdalene College
Magdalene College is deeply saddened to announce the death of Professor Sir John Gurdon FRS, who served as Master of the College from 1995 to 2002.
www.magd.cam.ac.uk
Reposted by Patrick Steinmetz
thibautbrunet.bsky.social
Latest from ours: www.cell.com/cell-reports...

This is two stories in one: a case study/cautionary tale on developing genetic tools in new organisms, and the first hint at a gene regulatory network for choanoflagellate multicellular development (which turn out to involve a Hippo/YAP/ECM loop!) A 🧵
prhsteinmetz.bsky.social
@malinkjosavik.bsky.social was fantastic giving her first talk at a conference!
msarscentre.bsky.social
Fantastic presentation by @malinkjosavik.bsky.social at the Tutzing basal metazoan workshop 👏 She shared her work on starvation and metabolism in Nematostella, conducted in collaboration between the @prhsteinmetz.bsky.social lab and the Dept of Biomedicine @unibergen.bsky.social
Reposted by Patrick Steinmetz
msarscentre.bsky.social
Fantastic presentation by @malinkjosavik.bsky.social at the Tutzing basal metazoan workshop 👏 She shared her work on starvation and metabolism in Nematostella, conducted in collaboration between the @prhsteinmetz.bsky.social lab and the Dept of Biomedicine @unibergen.bsky.social
Reposted by Patrick Steinmetz
carlzimmer.com
How Did Hands Evolve? The Answer Is Behind You. (My story of some surprising evo-devo!) nyti.ms/42Cg8xH
Gray's Anatomy illustration of a hand
Reposted by Patrick Steinmetz
aurhin.bsky.social
Are digits modified fins, or evolutionary innovations? Read how we tackled this old question from a new angle🧪
A story with @chasebolt.bsky.social, @homeobox.bsky.social and myself, coordinated by @denisduboule.bsky.social from @college-de-france.fr and published in @nature.com today!
#InHoxWeTrust
hoxd13a reporter in a zebrafish larva
Reposted by Patrick Steinmetz
lcochella.bsky.social
Our work on the function of miR-51/miR-100 is out! miR-100 is widely conserved across eumetazoans but its function has been mysterious. Emilio Santillán found in worms it regulates signaling and extracellular matrix genes, some of which seem to be conserved targets! www.science.org/doi/10.1126/...
An ancient and essential miRNA family controls cellular interaction pathways in C. elegans
A microRNA that arose at the origin of eumetazoans regulates cell adhesion and signaling in C. elegans through conserved targets.
www.science.org
Reposted by Patrick Steinmetz
ulrichtechnau.bsky.social
Finally, the excellent postdoc work of Emmanuel Haillot is out, where he dissected the integration of Wnt, MAPK and Notch signaling in defining mesoderm and endoderm identities in the diploblast Nematostella. Strikingly similar to sea urchins. www.nature.com/articles/s41...
Reposted by Patrick Steinmetz
jekely.biologists.social.ap.brid.gy
At long last, the version of record of our paper on the #platynereis #connectome

"Whole-body connectome of a segmented annelid larva" is out.

Explore the rich online presentation with all the videos, figures and source data here:

https://doi.org/10.7554/eLife.97964

@eLife
@biology […]
Original post on biologists.social
biologists.social
Reposted by Patrick Steinmetz
msarscentre.bsky.social
Congratulations Dr. Fournon Berodia @inesfournon.bsky.social 🎉🤩 We are very proud of Inés for successfully defending her PhD thesis conducted in the @prhsteinmetz.bsky.social lab. Thank you to opponents @ragkousik.bsky.social & @levayerr.bsky.social for insightful discussions 👏
Inés Fournon Berodia presents in front of an audience. She is wearing a black blazer and a white shirt. The slide on the screen has a black background, and reads "Hallmarks of epithelial cell extrusion". Below the title, a schematic of an epithelium, and the following text in bullet points: "Mitogen Activated Protein Kinase (MAPK)", "Facilitate extrusion" and "Protect surrounding cells" Ines Fournon Berodia smiles widely, holding in place on her head a customized graduation hat.
Reposted by Patrick Steinmetz
msarscentre.bsky.social
New preprint from the @pawelburkhardt.bsky.social lab 🤩 @annaferraioli.bsky.social & colleagues created a 3D model of the ctenophore apical organ, revealing cell-type diversity and exciting new insights into the evolution of central nervous systems 🧠🧪 Congratulations to the team! 👏
pawelburkhardt.bsky.social
Ctenophores possess a unique aboral organ that acts as a multisensory center, controlling complex behaviors. We’ve now created a ctenophore model integrated with our 3D volume EM data. Puts it into perspective.

Check out our recent work here: www.biorxiv.org/content/10.1...

#ctenophores #volumeEM
Reposted by Patrick Steinmetz
msarscentre.bsky.social
Researchers from @imev-mer.fr recently visited us for a workshop supported by the French-Norwegian mobility program Åsgard 🌊 Between seminars, lab demos and discussions, new ideas and plans for long-term collaborations emerged 🤩 Read more about this exciting partnership below ⤵️
Åsgard workshop sparks new collaborations at the Michael Sars Centre
Researchers from the Institut de la Mer de Villefranche and the Michael Sars Centre received support from the French-Norwegian mobility program Åsgard. Through seminars and discussions, participants l...
tinyurl.com
Reposted by Patrick Steinmetz
juliusbrennecke.bsky.social
Pls. share widely

Calling all transposon fans & lovers of genetic innovation

MOBILE GENOME welcomes you in Heidelberg, Nov. 4–7 2025

→ Vibrant & friendly community
→ Cutting-edge talks from mechanisms to physiology
→ Plenty of surprises (TEs never stop innovating)

submit abstract by July 29
events.embl.org
⏰ Abstract deadline for 'The mobile genome' is 29 July!

👉 https://s.embl.org/mge25-01-bl

Join us 4–7 Nov 2025 at EMBL Heidelberg (or online) to explore the impact of TEs across biology. 🧬🔍

⭐🧑🏼‍🔬 24 talks + 15 flash talks from posters – don't miss out!

#EMBOMobileGenome
Reposted by Patrick Steinmetz
merriam-webster.com
'Vacations.'

The word is 'vacations.'

FAST COMPANY Article: 

While retirement typically occurs, after
completing a career and saving and investing for it, a new trend is emerging among Gen Z career professionals
called "micro-retirement." Micro-
retirements involve taking a one to two- week break from work every 12 to 18 months.
Gen Z is using micro-retirement to avoid burnout, find greater fulfillment in their work, and enhance their overall well-being. However, it's not just Gen-Z:
Reposted by Patrick Steinmetz
nathaliereuter.bsky.social
Open PhD position in my group: protein bioinformatics and protein-lipid interactions. Competences required: experience with protein bioinformatics, good programing skills, machine learning, interest for beautiful protein structures! Deadline: Aug 1st 2025. Official info => tinyurl.com/LTPbioinfo
PhD Research Fellow in protein bioinformatics  (282926) | University of Bergen
Job title: PhD Research Fellow in protein bioinformatics  (282926), Employer: University of Bergen, Deadline: Tuesday, July 15, 2025
tinyurl.com
prhsteinmetz.bsky.social
Likely a dice snake (Natrix tessellata)
Reposted by Patrick Steinmetz
xgrau.bsky.social
A single-cell ATACseq atlas of our favourite sea anemone, Nematostella vectensis! By @aelek.bsky.social @martaig.bsky.social
UMAP 2D projections of single-cell ATAC atlases of a Nematostella gastrula (left) and an adult specimen (right)
Reposted by Patrick Steinmetz
Reposted by Patrick Steinmetz
trevorabranch.bsky.social
Foundations: please step up and take over the Biodiversity Heritage Library (BHL). This is an absolutely essential scanned archive of all of the old journals and books from the 1500s to about 1920. Has been indispensable for my research.
about.biodiversitylibrary.org/call-for-sup...
Call for Support: – About BHL
about.biodiversitylibrary.org
Reposted by Patrick Steinmetz
kei-jokura.bsky.social
Our latest preprint is out!
www.biorxiv.org/content/10.1...

How do #ctenophores control their sense of balance "without a brain"?

We used connectomics to uncover the neural network behind their gravity sensing!