@rach-g.bsky.social
International Collaboration to Develop and Harmonize Drug Interaction Guidance for Nirmatrelvir/Ritonavir During COVID-19: Lessons Learned for Future Pandemic Preparedness
✅ Just Accepted
🔗 https://bit.ly/43TxFlJ
✅ Just Accepted
🔗 https://bit.ly/43TxFlJ
November 9, 2025 at 4:58 AM
Alarming prevalence of gonococcal ceftriaxone resistance in Vietnam ? role of periodic presumptive antimicrobials?
✅ Just Accepted
🔗 https://bit.ly/4osBTJg
✅ Just Accepted
🔗 https://bit.ly/4osBTJg
November 9, 2025 at 4:58 AM
Safety and Efficacy of Pemivibart, a Long-Acting Monoclonal Antibody, for Prevention of Symptomatic COVID-19: Interim Results From a Phase 3 Randomized Clinical Trial (CANOPY)
#IDSky
#IDSky
Safety and Efficacy of Pemivibart, a Long-Acting Monoclonal Antibody, for Prevention of Symptomatic COVID-19
We report an interim analysis of safety and efficacy of pemivibart in individuals with (cohort A) or without (cohort B) significant immunocompromise in the phase 3 CANOPY trial.
bit.ly
November 1, 2025 at 10:12 PM
Fitness of SARS-CoV-2 Omicron Subvariants in Respiratory and Gastrointestinal Cell Lines as Determined by Reverse-Transcription Droplet Digital PCR and Whole-Genome Sequencing
#IDSky
#IDSky
Fitness of SARS-CoV-2 Omicron Subvariants in Respiratory and Gastrointestinal Cell Lines as Determined by Reverse-Transcription Droplet Digital PCR and Whole-Genome Sequencing
The fitness of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariants was determined in human epithelial and continuous cells of the respiratory and gastrointestinal tracts
bit.ly
November 1, 2025 at 10:11 PM
A Miniaturized Assay to Evaluate Plasmodium cynomolgi and Plasmodium knowlesi as Models for Prioritizing Plasmodium vivax Vaccine Targets
#IDSky
#IDSky
A Miniaturized Assay to Evaluate Plasmodium cynomolgi and Plasmodium knowlesi as Models for Prioritizing Plasmodium vivax Vaccine Targets
Plasmodium vivax vaccine discovery lags behind Plasmodium falciparum due to the absence of a reliable in vitro culture system.
bit.ly
October 27, 2025 at 3:52 AM
Distinct defects in marginal zone B cells and filtration function characterize hyposplenism in persons with HIV on prolonged ART
✅ Just Accepted
#IDSky
🔗 https://bit.ly/3LasAPr
✅ Just Accepted
#IDSky
🔗 https://bit.ly/3LasAPr
October 27, 2025 at 3:51 AM
Prevalence and factors associated with Aspergillus galactomannan antigenemia among People Living with Advanced HIV Disease in Uganda
✅ Just Accepted
#IDSky
🔗 https://bit.ly/47pxHE4
✅ Just Accepted
#IDSky
🔗 https://bit.ly/47pxHE4
October 19, 2025 at 5:35 AM
The gut as a source of infection for fungal pathogens: increased fecal Candida albicans precedes onset of Candida late-onset sepsis in very preterm infants
✅ Just Accepted
#IDSky
✅ Just Accepted
#IDSky
The gut as a source of infection for fungal pathogens: increased fecal Candida albicans precedes onset of Candida late-onset sepsis in very preterm infants
The skin-to-blood route is traditionally considered the main pathway in Candida late-onset sepsis (LOS) development in preterm infants.
bit.ly
October 19, 2025 at 5:35 AM
Safety of Bacillus Calmette-Guérin vaccination and impact on HIV-1 latent reservoir size in people with treated HIV-1 Infection
✅ Just Accepted
#IDSky
🔗 https://bit.ly/4o3I5a5
✅ Just Accepted
#IDSky
🔗 https://bit.ly/4o3I5a5
October 11, 2025 at 10:55 PM
Antiretroviral Therapy Within 2 Years of HIV Acquisition Is Associated With Fewer Viral Blips: A Retrospective Analysis of More Than 20 Years of Data From the US Military HIV Natural History Study
#IDSky
#IDSky
Antiretroviral Therapy Within 2 Years of HIV Acquisition Is Associated With Fewer Viral Blips: A Retrospective Analysis of More Than 20 Years of Data From the US Military HIV Natural History Study
Viral blips have been associated with larger reservoir size and slower decay. Earlier antiretroviral therapy (ART) initiation may decrease the risk of blips.
bit.ly
October 11, 2025 at 10:53 PM
Effectiveness of COVID-19 vaccination and prior infections to reduce long COVID risk during the pre-Omicron and Omicron periods
✅ Just Accepted
#IDSky
🔗 https://bit.ly/4o1oLdK
✅ Just Accepted
#IDSky
🔗 https://bit.ly/4o1oLdK
October 5, 2025 at 9:41 PM
A Phase 1 Study in Healthy Subjects to Evaluate the Safety and Pharmacokinetics of a Human Monoclonal Antibody (S315) Against Diphtheria Toxin
#IDSky
https://bit.ly/4nHpmBp
#IDSky
https://bit.ly/4nHpmBp
A Phase 1 Study in Healthy Subjects to Evaluate the Safety and Pharmacokinetics of a Human Monoclonal Antibody (S315) Against Diphtheria Toxin
The standard of care of diphtheria is in critically short supply globally. We report here a phase 1 study of a human monoclonal antibody against diphtheria
bit.ly
October 5, 2025 at 9:41 PM
For the first time, @imperialcollegeldn.bsky.social, @ucl.ac.uk & @uniofnottingham.bsky.social scientists have captured in detail how life-saving #antibiotics break through bacterial armour.
The findings could help tackle deadly drug-resistant infections.
www.imperial.ac.uk/news/269074/...
The findings could help tackle deadly drug-resistant infections.
www.imperial.ac.uk/news/269074/...
Amazing images show how antibiotics pierce bacterial armour | Imperial News | Imperial College London
UK researchers have shown for the first time in stunning detail how life-saving antibiotics act against harmful bacteria.
www.imperial.ac.uk
September 29, 2025 at 2:50 PM
🐾 #WorldRabiesDay reminder:
#rabies is almost always fatal once symptoms appear - but 100% preventable.
𝗜𝗳 𝗯𝗶𝘁𝘁𝗲𝗻/𝘀𝗰𝗿𝗮𝘁𝗰𝗵𝗲𝗱 𝗯𝘆 𝗮 𝗺𝗮𝗺𝗺𝗮𝗹:
❗ Wash the wound with soap & water immediately.
❗ Seek medical advice without delay. A doctor will assess your risk & if needed, start post-exposure vaccination.
#rabies is almost always fatal once symptoms appear - but 100% preventable.
𝗜𝗳 𝗯𝗶𝘁𝘁𝗲𝗻/𝘀𝗰𝗿𝗮𝘁𝗰𝗵𝗲𝗱 𝗯𝘆 𝗮 𝗺𝗮𝗺𝗺𝗮𝗹:
❗ Wash the wound with soap & water immediately.
❗ Seek medical advice without delay. A doctor will assess your risk & if needed, start post-exposure vaccination.
September 29, 2025 at 1:48 PM
Changes in Bone Microarchitecture and Inflammatory Cytokines after Cure of Chronic Hepatitis C Infection With Direct-Acting Antiviral Therapy
✅ Just Accepted
#IDSky
✅ Just Accepted
#IDSky
Changes in Bone Microarchitecture and Inflammatory Cytokines after Cure of Chronic Hepatitis C Infection With Direct-Acting Antiviral Therapy
AbstractBackground. It remains unclear if cure of hepatitis C virus (HCV) infection with direct-acting antivirals (DAAs) ameliorates HCV-related inflammati
doi.org
September 22, 2025 at 9:16 PM
Measles cases up 31-fold in the Americas region this year
The Americas region have reported 11,313 cases so far this year.
www.cidrap.umn.edu/m...
The Americas region have reported 11,313 cases so far this year.
www.cidrap.umn.edu/m...
September 22, 2025 at 9:16 PM
Quick takes: Mosquito-borne illness in Europe, polio in 3 nations, avian flu hits more US poultry
France and Italy continue to battle chikungunya outbreaks and the spread of dengue, as Greece probes possible local malaria cases.
France and Italy continue to battle chikungunya outbreaks and the spread of dengue, as Greece probes possible local malaria cases.
Quick takes: Mosquito-borne illness in Europe, polio in 3 nations, avian flu hits more US poultry
France and Italy continue to battle chikungunya outbreaks and the spread of dengue, as Greece probes possible local malaria cases.
www.cidrap.umn.edu
September 13, 2025 at 9:20 PM
September 13, 2025 at 9:20 PM
September 6, 2025 at 9:13 PM
Long-acting cabotegravir/rilpivirine in viraemic people with HIV: bumpy raod to perfection
✅ Just Accepted
#IDSky
✅ Just Accepted
#IDSky
Long-acting cabotegravir/rilpivirine in viraemic people with HIV: bumpy raod to perfection
bit.ly
September 6, 2025 at 9:12 PM
Study ties longer placement of peripheral catheters to higher risk of bloodstream infections
A study of patients with peripheral intravenous catheters finds a significantly increased risk of BSIs after 3 days of dwell time.
www.cidrap.umn.edu/h...
A study of patients with peripheral intravenous catheters finds a significantly increased risk of BSIs after 3 days of dwell time.
www.cidrap.umn.edu/h...
April 26, 2025 at 6:18 PM
Utilizing HIV Proviral DNA to Assess for the Presence of HIV Drug Resistance
⭐ Editor's Choice
#IDSky
⭐ Editor's Choice
#IDSky
Utilizing HIV Proviral DNA to Assess for the Presence of HIV Drug Resistance
The improved efficacy and tolerability of newer antiretroviral drugs, as well as the introduction of long-acting regimens, have prompted more frequent therapy switches in individuals on suppressive antiretroviral therapy (ART).
academic.oup.com
April 26, 2025 at 6:17 PM
Increased atherosclerosis in HIV-infected humanized mice is caused by a single viral protein, Nef
✅ Just Accepted
#IDSky
✅ Just Accepted
#IDSky
Increased atherosclerosis in HIV-infected humanized mice is caused by a single viral protein, Nef
Antiretroviral therapy (ART) suppresses HIV replication, reverses immunodeficiency, and reduces AIDS-related symptoms, but non-AIDS co-morbidities like cardiovascular diseases remain a major challenge for people living with HIV (PLWH).
doi.org
April 20, 2025 at 10:39 PM
Proportions of U.S. Blood Donors with Serological Evidence of SARS-CoV-2 Infections Who Reported Survey-Based Diagnosed Infections During July 2020-December 2022
✅ Just Accepted
#IDSky
✅ Just Accepted
#IDSky
Proportions of U.S. Blood Donors with Serological Evidence of SARS-CoV-2 Infections Who Reported Survey-Based Diagnosed Infections During July 2020-December 2022
The proportion of SARS-CoV-2 infections diagnosed by COVID-19 tests, including home antigen tests, is unknown. We detected infections among U.S. blood donors by testing for nucleocapsid antibody (anti-N) seroconversion and administered a questionnaire to determine the proportion of those infections that were associated with a self-reported positive COVID-19 test.
doi.org
April 20, 2025 at 10:37 PM
Salmonella enterica with bla OXA-181 gene may have recently emerged in the human population of northern Italy
Just a few months after it was detected in the pig population. A likely consequence of zoonotic transmission along the food chain
#IDSky #EpiSky #OneHealth #PublicHealth 🦠 #FoodSafety #AMR
Just a few months after it was detected in the pig population. A likely consequence of zoonotic transmission along the food chain
#IDSky #EpiSky #OneHealth #PublicHealth 🦠 #FoodSafety #AMR
Emergence of Salmonella enterica carrying blaOXA-181 carbapenemase gene, Italy, 2021 to 2024
Between 2021 and 2024, we detected carbapenemase gene blaOXA-181 in 16 of 11,398 Salmonella enterica (SE) isolates: 10 SE 1,4,[5],12:i:-, three Bovismorbificans, two London and one Rissen from pigs, h...
www.eurosurveillance.org
April 10, 2025 at 7:16 PM