Rajitha Udakara Sampath Hemba-Waduge
@rajitha91.bsky.social
Regional adipocyte heterogeneity supports metabolic homeostasis, yet mechanisms remain unclear. This study reveals that the interplay between Wnt/Wingless signaling and Hox proteins (Abd-A and Abd-B) defines the regional heterogeneity in Drosophila.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Adipocyte heterogeneity regulated by the Bithorax Complex-Wnt signaling crosstalk in Drosophila - EMBO Reports
Adipocytes play essential roles in lipid metabolism and energy homeostasis, with regional differences affecting their functions and disease susceptibility. However, the mechanisms underlying this regi...
link.springer.com
December 7, 2025 at 8:34 AM
Regional adipocyte heterogeneity supports metabolic homeostasis, yet mechanisms remain unclear. This study reveals that the interplay between Wnt/Wingless signaling and Hox proteins (Abd-A and Abd-B) defines the regional heterogeneity in Drosophila.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Reposted by Rajitha Udakara Sampath Hemba-Waduge
Transcriptional Regulation of Lipid Metabolism by Wnt Signaling and Hox Protein Cues
#Drosophila
#Drosophila
Transcriptional Regulation of Lipid Metabolism by Wnt Signaling and Hox Protein Cues
#Drosophila
PubMed link
pubmed.ncbi.nlm.nih.gov
August 1, 2025 at 5:23 AM
Transcriptional Regulation of Lipid Metabolism by Wnt Signaling and Hox Protein Cues
#Drosophila
#Drosophila
Transcriptional coupling of telomeric retrotransposons with the cell cycle | Science Advances www.science.org/doi/full/10....
Transcriptional coupling of telomeric retrotransposons with the cell cycle
The life cycle of telomeric retrotransposons is transcriptionally linked to host cell-cycle machinery via E2F1 in Drosophila.
www.science.org
September 9, 2025 at 7:41 AM
Transcriptional coupling of telomeric retrotransposons with the cell cycle | Science Advances www.science.org/doi/full/10....
Distinct effects of CDK8 module subunits on cellular growth and proliferation in Drosophila url: journals.biologists.com/dev/article/...
Distinct effects of CDK8 module subunits on cellular growth and proliferation in Drosophila | Development | The Company of Biologists
journals.biologists.com
September 9, 2025 at 7:41 AM
Distinct effects of CDK8 module subunits on cellular growth and proliferation in Drosophila url: journals.biologists.com/dev/article/...
Wnt/Wingless signaling promotes lipid mobilization through signal-induced transcriptional repression | PNAS www.pnas.org/doi/abs/10.1...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
September 8, 2025 at 6:03 PM
Wnt/Wingless signaling promotes lipid mobilization through signal-induced transcriptional repression | PNAS www.pnas.org/doi/abs/10.1...
Reposted by Rajitha Udakara Sampath Hemba-Waduge
Liu, M., Xie, X. J., Li, X., Ren, X., Sun, J., Lin, Z., Hemba-Waduge, R. U., Ji, J. Y. (2023). Transcriptional coupling of telomeric retrotransposons with the cell cycle. bioRxiv, www.biorxiv.org/content/10.1...
May 21, 2024 at 8:13 PM
Liu, M., Xie, X. J., Li, X., Ren, X., Sun, J., Lin, Z., Hemba-Waduge, R. U., Ji, J. Y. (2023). Transcriptional coupling of telomeric retrotransposons with the cell cycle. bioRxiv, www.biorxiv.org/content/10.1...
Reposted by Rajitha Udakara Sampath Hemba-Waduge
Hemba-Waduge, R. U., Liu, M., Li, X., Sun, J. L., Budslick, E. A., Bondos, S. E., Ji, J. Y. (2024). Metabolic control by the Bithorax Complex-Wnt signaling crosstalk in Drosophila. bioRxiv, www.biorxiv.org/content/10.1...
March 5, 2025 at 10:25 PM
Hemba-Waduge, R. U., Liu, M., Li, X., Sun, J. L., Budslick, E. A., Bondos, S. E., Ji, J. Y. (2024). Metabolic control by the Bithorax Complex-Wnt signaling crosstalk in Drosophila. bioRxiv, www.biorxiv.org/content/10.1...
Reposted by Rajitha Udakara Sampath Hemba-Waduge
Liu, M., Hemba-Waduge, R. U., Li, X., Huang, X., Liu, T. H., Han, X., Wang, Y., Ji, J. Y. (2024)s. Wnt/Wingless signaling promotes lipid mobilization through signal-induced transcriptional repression.. JProc Natl Acad Sci U S A, 121(28):e2322066121 www.pnas.org/doi/abs/10.1...
Wnt/Wingless signaling promotes lipid mobilization through signal-induced transcriptional repression | PNAS
The Wnt/Wingless signaling pathway plays critical roles in metazoan development and
energy metabolism, but its role in regulating lipid homeostasis...
www.pnas.org
May 23, 2025 at 6:00 AM
Liu, M., Hemba-Waduge, R. U., Li, X., Huang, X., Liu, T. H., Han, X., Wang, Y., Ji, J. Y. (2024)s. Wnt/Wingless signaling promotes lipid mobilization through signal-induced transcriptional repression.. JProc Natl Acad Sci U S A, 121(28):e2322066121 www.pnas.org/doi/abs/10.1...