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rangachari lab (vijay) @rangacharilab.bsky.social · Jun 28

The organizing committee: Vijay Rangachari bsky.app/profile/rang..., Anant Paravastu, Ayanjeet Ghosh, and Ayyalusamy Ramamoorthy.

rangachari lab (vijay) @rangacharilab.bsky.social · Jun 28

We have an incredible lineup of speakers this year, highlighted by the Keynote by Jennifer Lee, NHLBI. We want to thank our sponsors: The University of Southern Mississippi, bsky.app/profile/uofa..., Alabama; bsky.app/profile/gtre...; and Photothermal Spectroscopy Corp.

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rangachari lab (vijay) @rangacharilab.bsky.social · Jun 28

We are excited to launch the SouthEast Amyloid CONdensate (SEACON) symposium!! Our inaugural meeting will take place in Ocean Springs, MS, in August 2025. For details, please visit:

www.rangacharilab.com/1st-seacon-s...

SEACON Symposium — www.rangacharilab.com

www.rangacharilab.com

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rangachari lab (vijay) @rangacharilab.bsky.social · Jun 7

Nice work, Samrat!

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rangachari lab (vijay) @rangacharilab.bsky.social · May 24

@malaymondal.bsky.social led an exceptional work supported by collaboration with the Clemons, Bai, and Huang labs.
This is a follow-up from our previous work on disulfide bond cross-linked condensates: pubs.acs.org/doi/10.1021/...

Reversible Disulfide Bond Cross-Links as Tunable Levers of Phase Separation in Designer Biomolecular Condensates

Biomolecular condensates (BCs) are membraneless hubs enriched with proteins and nucleic acids that have emerged as important players in many cellular functions. Uncovering the sequence determinants of...

pubs.acs.org

rangachari lab (vijay) @rangacharilab.bsky.social · May 24

Excited to share our new data on the use of redox-sensitive peptide condensates as cell delivery vehicles. We show that our peptide condensates can efficiently deliver a variety of small molecules, DNA, mRNA, and proteins, to the cellular cytoplasm.
www.biorxiv.org/content/10.1....

Disulfide cross-linked redox-sensitive peptide condensates are efficient cell delivery vehicles of molecular cargo.

Biomolecular condensates (BCs) are phase-separated viscoelastic hubs within demixed solutions enriched in proteins and nucleic acids. Such condensates, also called membraneless organelles, are increas...

www.biorxiv.org

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rangachari lab (vijay) @rangacharilab.bsky.social · Mar 13

Excited to share our latest work on amyloid-synthetic polymer blends. pubs.acs.org/doi/10.1021/...

De Novo Amyloid Peptide–Polymer Blends with Enhanced Mechanical and Biological Properties

Amyloid peptides are structurally diverse materials that exhibit different properties depending on their self-assembly. While they are often associated with neurodegenerative diseases, functional amyl...

pubs.acs.org

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rangachari lab (vijay) @rangacharilab.bsky.social · Feb 19

nuts..

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rangachari lab (vijay) @rangacharilab.bsky.social · Feb 17

Want to know about #IDPs? Why not hear from @rohitpappu68.bsky.social in his typical éloquence royale?

WebsEdge Science @websedgescience.bsky.social · Feb 17

For our first scientific session spotlight we are "Peeking away from the lampost" with Dr. Rohit Pappu as he joins us to discuss intrinsically disordered proteins. @rohitpappu68.bsky.social @biophysicalsoc.bsky.social #bps2025 youtu.be/pAP2lBWBiGU

Intrinsically Disordered Proteins: A Peek Away from the Lampost

YouTube video by WebsEdge Science

youtu.be

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rangachari lab (vijay) @rangacharilab.bsky.social · Feb 8

Oh am sure every $ spent on $750b military is legit… saving $12b by killing science and bright minds is worth it..
grants.nih.gov/grants/guide...

NOT-OD-25-068: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates

NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates NOT-OD-25-068. OD

grants.nih.gov

rangachari lab (vijay) @rangacharilab.bsky.social · Jan 1

Congrats, Alex!

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rangachari lab (vijay) @rangacharilab.bsky.social · Jan 1

Wishing you all a peaceful, healthy, and a prosperous 2025!!

rangachari lab (vijay) @rangacharilab.bsky.social · Dec 10

It was fantastic and humbling to receive a personal email from @J_A_C_S, the editor-in-chief, congratulating us on this work. Malay_Moldal and others deserve all the credit.👏

rangachari lab (vijay) @rangacharilab.bsky.social · Nov 13

Sharing our latest paper in the Journal of the American Chemical Society (JACS). We show that disulfide bond cross-links can reversibly tune the properties of #biomolecularcondensates to modulate their percolation behavior. pubs.acs.org/doi/10.1021/...

Reversible Disulfide Bond Cross-Links as Tunable Levers of Phase Separation in Designer Biomolecular Condensates

Biomolecular condensates (BCs) are membraneless hubs enriched with proteins and nucleic acids that have emerged as important players in many cellular functions. Uncovering the sequence determinants of...

pubs.acs.org

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rangachari lab (vijay) @rangacharilab.bsky.social · Dec 5

see related conference: nationalmaglab.org/news-events/...

nationalmaglab.org

rangachari lab (vijay) @rangacharilab.bsky.social · Dec 5

NEW SOCIETY ALERT! "International Society for Proteinopathies" is a group focused on pathomechanisms of protein-misfolding diseases. If you are interested in protein aggregation and phase transitions, this is for you.
Please come on board with us..
www.proteinopathies.org

HOME | proteinopathies.org

www.proteinopathies.org

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rangachari lab (vijay) @rangacharilab.bsky.social · Nov 27

A significant discovery elegantly demonstrated...
www.nature.com/articles/s41...

Stereochemistry in the disorder–order continuum of protein interactions - Nature

Studies on protein–protein interactions using proteins containing d- or l-amino acids show that stereoselectivity of binding varies with the degree of disorder within the complex.

www.nature.com

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rangachari lab (vijay) @rangacharilab.bsky.social · Nov 25

Check out our chapter on "Amyloid Polymorphism" in the book "The Three Functional States of Proteins."
www.sciencedirect.com/science/arti...

Structural polymorphism in amyloids—states within proteins’ solid-state

Proteins are functionally diverse molecules that exist in a plethora of conformations and structures or as disordered ensembles, depending on their pr…

www.sciencedirect.com

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rangachari lab (vijay) @rangacharilab.bsky.social · Nov 23

Welcome…

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Reposted by rangachari lab (vijay)

Altmetric @altmetric.com · Nov 18

We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how:

docs.bsky.app/docs/advance...

#AcademicSky #HigherEd #Altmetrics

Action Intent Links | Bluesky

Authors, websites, and apps can use action intent links to implement "Share on Bluesky" buttons, or similar in-app actions. Logged-in users will be directed to the corresponding action view in the Blu...

docs.bsky.app

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rangachari lab (vijay) @rangacharilab.bsky.social · Nov 18

www.fiercebiotech.com/research/rep...

Report: Every dollar of NIH research funding doubles in economic returns

Research funded by the National Institutes of Health (NIH) generated $2.46 in economic activity for every $1 of funding in 2023, a total of $92.9 billion, according to an

www.fiercebiotech.com

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Reposted by rangachari lab (vijay)

David Kuster @rnadavid.bsky.social · Nov 18

Biomolecular condensate starter pack!

Trying to compile & to bring together biomolecular condensate enthusiasts & critics!

Please join this non-exhaustive (sorry!) collection & just ping me for addition.

#condensates, #phaseseparation, #granules, #IDPs

go.bsky.app/NFqmffa

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Reposted by rangachari lab (vijay)

Alex Holehouse @alexholehouse.bsky.social · Nov 10

BONUS! If IDPs are your jam, check out an ever-expanding starter pack!
go.bsky.app/J23B51L

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rangachari lab (vijay) @rangacharilab.bsky.social · Nov 15

Stunning..

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rangachari lab (vijay) @rangacharilab.bsky.social · Nov 15

A quintessential morning in southern India...

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rangachari lab (vijay) @rangacharilab.bsky.social · Nov 14

You have good students who care about you... enjoy, and happy birthday :)

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