Rangan Lab
@ranganlab.bsky.social
150 followers 190 following 7 posts
Germline development @IcahnMountSinai @CDRBSinai https://scholar.google.com/citations?user=GZS8SS4AAAAJ&hl=en
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ranganlab.bsky.social
New preprint from our lab!
biorxiv-devbio.bsky.social
TORC1-driven translation of Nucleoporin 44A promotes chromatin remodeling and germ cell-to-maternal transition in Drosophila https://www.biorxiv.org/content/10.1101/2025.03.14.643309v1
Reposted by Rangan Lab
fly-eds.bsky.social
The @fly-eds.bsky.social is having its general assembly this saturday at 13:30 at #EDRC2025 , please join us to discuss our society and to find out more about @flybase.bsky.social and the current funding crisis
Reposted by Rangan Lab
edrc2025.bsky.social
There are only 8 days left to register to @edrc2025.bsky.social and we would like to thank all our sponsorss! We start acknowledging the support received from @biologists.bsky.social to #EDRC2025 Thank you!
ranganlab.bsky.social
Registration is officially open for the 2026 EMBO Drosophila Meeting in Crete 🪰☀️. This flagship meeting brings together researchers from around the world to share discoveries, foster collaborations, and celebrate the power of Drosophila in advancing biology. Consider applying!
Reposted by Rangan Lab
dev-journal.bsky.social
Actin up: Mrtfa regulates actomyosin and apical constriction This Research Highlight showcases the work from Keiji Itoh, Olga Ossipova, Sergei Y. Sokol:

journals.biologists.com/dev/article/...
Fig. 3. Mrtfa depletion leads to reduced F-actin levels and increases apical domain size in the neural plate. (A) One dorso-animal site of eight-cell embryos was injected with control MO (Co MO) or Mrtfa-MOsp (40 ng each) with lineage tracer MyrGFP (10 pg) and allowed to develop until control embryos reached stage 16-17. (B-E) Neural plate was dissected from the injected embryos. Neural plate images from the CoMO- (B-B″) or Mrtf-MOsp (C-C″) -injected embryos at low (B,C) or high (B′,B″,C′,C″) magnification at the level of hindbrain. Midline is indicated with a white dashed line (B′,B″,C′,C″). Scale bars: 100 µm for B,C; 50 µm for B′,B″,C′,C″. (D) Quantification of F-actin intensity at the bicellular junctions (BCJs). Injected (GFP) and uninjected (Uni.) cells were scored in the neural plate at the hindbrain region, as indicated. N=numbers of junctions scored. (E) Quantification of apical domain size. N=numbers of cells scored. Kruskal–Wallis test: ****P<0.0001; n.s., not significant. The box plots indicate the median and quartiles.
Reposted by Rangan Lab
kgandersen.bsky.social
Here's the NIH's proposed budget - from $48 billion to $27 billion. NIAID, current ~$7 billion cut to ~$4.2 billion.

The proposed 15% cap on indirect costs remains.

Again, these budgets are passed, and our leadership in science, technology, and innovation is gone.

www.hhs.gov/sites/defaul...
Reposted by Rangan Lab
kgandersen.bsky.social
The end of US leadership in science, technology, and innovation.

All in one little table.

A tremendous gift to China, courtesy of the GOP.

nsf-gov-resources.nsf.gov/files/00-NSF...
Reposted by Rangan Lab
schiff.senate.gov
Science is under attack. The NIH, the NSF, and our research universities.

So today, I have a message for America's scientists:

youtu.be/MeoZDPy5cIY?...
A Message to Scientists
YouTube video by Sen. Adam Schiff
youtu.be
Reposted by Rangan Lab
harmitmalik.bsky.social
“Remember that all through history, there have been tyrants and murderers, and for a time, they seem invincible. But in the end, they always fall. Always.”

—Mahatma Gandhi
Reposted by Rangan Lab
gcrox.bsky.social
All of NIH funding to Northwestern University is frozen. This pause includes noncompeting approved funding, new and competing grants with fundable scores. No reimbursements for money already spent have been received since March. This situation is rarely reported so please Please get the word out!
Reposted by Rangan Lab
Reposted by Rangan Lab
princetonmolbio.bsky.social
Congratulations to the next Chair of the Dept. of Molecular Biology: Elizabeth (Liz) R. Gavis, the Damon B. Pfeiffer Professor in the Life Sciences and Assoc. Faculty in the Program in Quantitative and Computational Biology. Her term begins on July 1, 2025. molbio.princeton.edu/news/2025/ga...
Gavis named next Chair
Elizabeth (Liz) R. Gavis, the Damon B. Pfeiffer Professor in the Life Sciences in the Department of Molecular Biology and Associated Faculty in the Program in Quantitative and Computational Biology, h...
molbio.princeton.edu
ranganlab.bsky.social
Congrats Yukiko!
whiteheadinstitute.bsky.social
Whitehead Institute Member Yukiko Yamashita, who studies how genetic information is passed from parents to offspring, has been elected to the National Academy of Sciences. Full story on our website: wi.mit.edu/news/yukiko-...
Reposted by Rangan Lab
harmitmalik.bsky.social
Drosophila folks at the @genetics-gsa.bsky.social Fly meeting please take some time to thank the amazing organizers who put in a lot of hard work:
genetics-gsa.org/drosophila-2...

Special thanks to GSA folks especially the tireless Suzy Brown (who appears to run entirely on diet Mountain Dew)
Organizers - 66th Annual Drosophila Research Conference
Visit our website to learn more.
genetics-gsa.org
Reposted by Rangan Lab
mayavoichek.bsky.social
1/ Transposable elements are often called "jumping genes" because they mobilize within genomes. 🧬
But did you know they can also jump 𝘣𝘦𝘵𝘸𝘦𝘦𝘯 cells? 🤯
Our new study reveals how retrotransposons invade the germline directly from somatic cells.
www.biorxiv.org/content/10.1...
A short thread 🧵👇
Drosophila follicle showing retrotransposons (pink & yellow) expressed in somatic cells infecting the oocyte
Reposted by Rangan Lab
snickclunk.bsky.social
Sign up & spread the word to trainees about the 🪱C. elegans🪱 mentor match program!
They're also setting up peer-mentoring groups at ALL stages (even faculty!). Peer mentors have helped me keep my sanity & resolve in the tough times, and cheered me on in the good times. 🙌 Sign up to find your own!
javierapfeld.bsky.social
Worm people: We need YOU to help recruit more mentees for the C. elegans Community Mentor Match program! 🪱✨

📢 Help us sign up more mentees by sharing this this slide with your lab in your next lab meeting!
Join the C. elegans Community Mentor Match Program!
Join the C. elegans Community Mentor Match Program! sign up for mentors sign up for mentees and to join peer-mentoring groups https://forms.gle/DpGTWRMrNGL96wHy8 https://forms.gle/pVBD5DYGXyLT4waLA
docs.google.com
Reposted by Rangan Lab
biorxiv-devbio.bsky.social
TORC1-driven translation of Nucleoporin 44A promotes chromatin remodeling and germ cell-to-maternal transition in Drosophila https://www.biorxiv.org/content/10.1101/2025.03.14.643309v1
ranganlab.bsky.social
New preprint from our lab!
biorxiv-devbio.bsky.social
TORC1-driven translation of Nucleoporin 44A promotes chromatin remodeling and germ cell-to-maternal transition in Drosophila https://www.biorxiv.org/content/10.1101/2025.03.14.643309v1
Reposted by Rangan Lab
carolynbertozzi.bskyverified.social
We are in a biotech space race, cutting off basic science via slashing NIH and NSF funding robs the US of our competitive advantage: early innovation.
jmcoller.bsky.social
China is poised to dominate biotechnology in the 21st century - The Hill
Reposted by Rangan Lab
needhibhalla.bsky.social
““This crisis — and I’m not exaggerating by calling it a crisis — has already consumed one funding cycle…But if this block to publishing in the register continues on much longer, it’s going to swallow two funding cycles, and that will put many labs out of business.” @labonnelab.bsky.social
ranganlab.bsky.social
Follow!
standupforscience.bsky.social
Welcome to the Bluesky account for Stand Up for Science 2025!

Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide!

#scienceforall #sciencenotsilence