@rashabarakat.bsky.social
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Shameless self promotion of our new paper. So very excited to share our new work uncovering coupling of glutamate receptors ⚡️and RTKs to enable growth of low-grade gliomas 🧠 @gutmannlab.bsky.social @washuneurology.bsky.social
September 2, 2025 at 8:45 PM
Shameless self promotion of our new paper. So very excited to share our new work uncovering coupling of glutamate receptors ⚡️and RTKs to enable growth of low-grade gliomas 🧠 @gutmannlab.bsky.social @washuneurology.bsky.social
Reposted
We are so proud of Rasha and Rui's new paper! Their single cell reveals hidden diversity in CD8+ exhausted T cells across cancers, shedding light on why patients respond differently to immunotherapy and bringing us closer to more effective therapies. Don’t miss this exciting advance from our team!
Pan-cancer single cell transcriptomic clustering reveals heterogeneous CD8+ exhausted T cell populations with different immune checkpoint inhibitor responses
In most cancers, T lymphocytes comprise an essential cellular component of the non-neoplastic microenvironment, where they have the capacity to both suppress and support tumor growth. One specializ...
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August 4, 2025 at 2:41 PM
We are so proud of Rasha and Rui's new paper! Their single cell reveals hidden diversity in CD8+ exhausted T cells across cancers, shedding light on why patients respond differently to immunotherapy and bringing us closer to more effective therapies. Don’t miss this exciting advance from our team!
Reposted
Excited to share a new paper from @rashab.bsky.social on exhausted CD8 T cells and low grade brain tumors in #NF1.
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Human single cell RNA-sequencing reveals a targetable CD8+ exhausted T cell population that maintains mouse low-grade glioma growth
Nature Communications - With the emergence of immune checkpoint inhibitor therapies for cancer, the authors use single-cell sequencing to assess exhausted T cell content in human glioma samples and...
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November 28, 2024 at 1:34 PM
Excited to share a new paper from @rashab.bsky.social on exhausted CD8 T cells and low grade brain tumors in #NF1.
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