Ratnasekhar CH
@ratnasekharlab.bsky.social
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29 following
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Metabolomics Scientist & Assistant Professor. Previous postdoc fellow at University of Cambridge and Queen's University Belfast.
https://www.ratnasekhar-metabolomics-lab.com/
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Reposted by Ratnasekhar CH
Mike Murphy
@mitoredox.bsky.social
· Feb 19
Pro-inflammatory macrophages produce mitochondria-derived superoxide by reverse electron transport at complex I that regulates IL-1β release during NLRP3 inflammasome activation - Nature Metabolism
Casey et al. explore the basic mechanisms of mitochondrial superoxide production and its impact on interleukin-1β production in LPS-treated macrophages.
doi.org