GOOD NEWS! Researchers have discovered a powerful antibody, known as 04_A06, that is able to neutralize 98.5% of MORE THAN 300 different HIV strains AND permanently reduce HIV viral load to undetectable levels, making it one of the broadest-acting antibodies against HIV identified to date.

GOOD NEWS! Researchers have developed a new mRNA vaccine that has been shown to suppress abnormal blood vessel growth in the retina, offering hope to MILLIONS of patients with age-related vision loss. The vaccine triggered strong antibody responses that REDUCED retinal damage by UP TO 85%.

GOOD NEWS! Researchers have made a HUGE breakthrough towards a UNIVERSAL antiviral. By targeting sugar molecules found on the surface of many viruses that SHARE structural similarities, they identified FOUR compounds that successfully BLOCKED infections from SEVEN different viruses.

Congrats to you and the team! Playdate seasons feel like a spiritual successor to Satellaview — fun little surprises that everyone gets access to at the same time ^^

@lpil.uk Looks like Bases in Obsidian will be getting an API either the ability to create new views obsidian.md/changelog/20...

GOOD NEWS! Researchers have unveiled a promising new vaccine that generates a powerful immune response against HIV and other viruses including SARS-CoV-2 and influenza with just ONE dose. By combining immune-boosting adjuvants, the vaccine encourages the body to generate more antibody variations.

Well now, would you look at that?

A massive, 26-YEAR-LONG study of MORE THAN 2.4 MILLION people in Sweden found found NO EVIDENCE to support a causal link between acetaminophen (the API in Tylenol) use during pregnancy and increased risk of autism, ADHD, OR intellectual disability in children.

GOOD NEWS! For the first time ever, Huntington's disease has been successfully treated. A groundbreaking new miRNA treatment, AMT-130, slowed the progression of the disease by 75%. These results are likely to support the first approval of a genetic treatment for the rare neurodegenerative condition.

GOOD NEWS! A new cancer vaccine has shown progress in triggering POWERFUL and LASTING immune responses in patients with pancreatic AND colorectal cancer. The vaccine, known as ELI-002 2P, targets mutant KRAS proteins AND had a huge impact on PREVENTING or DELAYING cancer recurrence in patients.

It was meeting an out trans person that helped me realize I myself was trans.

It was other out trans people that helped me navigate transitioning.

And it was even more out trans people who inspired me to keep going when times were tough.

Now I am an out trans person, and I hope to inspire others.

I do feel like the Base functionality could become a modern-day Frontier with a bit of coaxing — I'm kinda tempted to explore some structural/outliner-based programming with it once the database becomes more accessible.

It’s a dichotomy based on my own (increasingly hazy) memories of being a student, but yes, a worksheet like this doesn’t have to be the only way to navigate inequities in class participation or the increasing ubiquity of LLMs. Are there other approaches that have worked for you?

Maybe it's because I haven't been an MPP student in ages (no laptop or phone), but this approach doesn't strike me as infantalizing. I think I would have preferred this back in the day vs. just opening up the floor to whoever's most comfortable speaking 1st. Even pro athletes still have to warm up!

WELL NOW, would you look at that? A massive GLOBAL study revealed COVID-19 vaccines utilizing mRNA technology PREVENTED OVER 2.5 MILLION deaths WORLDWIDE between 2020 and 2024.

It reveals that vaccinations didn’t JUST protect against illness.

They PRESERVED nearly 15 MILLION years of human life.

@theerlef.bsky.social Good to see the EEF on bluesky! Small suggestion: Add the EEF website link to the account bio so people can check it out ^^

The EEF can also verify the erlef.org domain for use on bsky: seanthegeek.net/posts/how-bl...

GOOD NEWS! For the FIRST time ever, and after MORE THAN 30 YEARS of HIV vaccine clinical trials, researchers have developed a vaccine that has SUCCESSFULLY generated TIER 2 broadly neutralizing antibodies (bnAbs) against HIV and BLOCKS viral infection in vaccinated PEOPLE.

GOOD NEWS! Researchers at the University of Florida have developed a UNIVERSAL vaccine that dramatically BOOSTS the immune system’s ability to fight tumors- even WITHOUT targeting a SPECIFIC cancer type. It has the potential to do away with chemotherapy, surgery AND radiation treatment.

Vaccines save lives. They are safe and effective.

And no, they do not cause autism.

Thank you for writing this piece!

Regarding VRAM limits and running LLMs locally, prices are starting to get in the prosumer range:

- 64GB of unified memory + a decent iGPU/NPU can be had for ~$1800 (Framework Desktop) or $2000 (Mac mini)

- 128GB version of the Framework costs ~$2200

WELL NOW, would you look at that? A massive, 24-YEAR-LONG study of MORE THAN 1.2 MILLION people in Denmark found NO LINK between aluminum in childhood vaccines and autism, asthma, OR chronic disorders.

Aluminum is an ADJUVANT.

It ENHANCES your immune response to a vaccine.

That’s it.

GOOD NEWS! Researchers have revealed a synthetic glycosystem -a sugar-coated polymer nanoparticle- that can BLOCK SARS-CoV-2 from infecting human cells, REDUCING infection rates by NEARLY 99%. Acting as a decoy, the molecule BINDS to the spike protein, PREVENTING it from attaching to real cells.

Perfect Dark can be played with modern controls via Rare Replay — it has a decidedly non-metal soundtrack with songs such as

m.youtube.com/watch?v=sDmz...

and

m.youtube.com/watch?v=4CMN...