imageimageAn intergenerational cycle between HRDE-1 and WAGO-3 drives RNAi inheritance in C. elegans, where HRDE-1 drives silencing in both parent and offspring and WAGO-3 transmits the RNAi response ...

Kar et al. demonstrate that Balbiani body (Bb) formation is achieved via developmental condensation in zebrafish oogenesis, driven by Buc phase separation and evolving from a dynamic liquid-like state into a solid-like stable compartment. Multistep regulation by microtubules controls condensation, ensuring proper Bb formation and oocyte polarity.

Johannes Gutenberg-Universität Mainz looks for University Professor of Life History Evolution W3 in Mainz - apply now!

IMB Mainz

FMI researchers have developed a new tool that maps how proteases —enzymes that process proteins— cut their targets. This innovation offers new insight into the highly selective nature of proteases, w...

Zhou et al. discovered a specific role of adenosine modifications in the coding region of mRNAs. These chemical alterations slow down the movement of the ribosome during translation and trigger degrad...