ronnyhelman.bsky.social
Ronny Helman
@ronnyhelman.bsky.social
28 followers 71 following 1 posts
https://www.helmanlab.com
www.helmanlab.com
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kalwat.bsky.social
Mike Kalwat @kalwat.bsky.social · May 19
Actin remodeling in beta cells adds new layers of upstream regulation - Congrats! @ronnyhelman.bsky.social
ronnyhelman.bsky.social
Ronny Helman @ronnyhelman.bsky.social · May 18
Happy to share a work from the Helman lab on how beta cells sense and control their insulin secretion by Krell et al. in @CellReports.

Beta cells intrinsically sense and limit their secretory activity via mTORC1-RhoA signaling: Cell Reports www.cell.com/cell-reports...
Beta cells intrinsically sense and limit their secretory activity via mTORC1-RhoA signaling
Krell et al. show that mTORC1 in β cells acts as an activity sensor, activated by the same signals that trigger insulin secretion. This activation, in turn, inhibits insulin release via RhoA-dependent...
www.cell.com
2 3
ronnyhelman.bsky.social
Ronny Helman @ronnyhelman.bsky.social · May 18
Happy to share a work from the Helman lab on how beta cells sense and control their insulin secretion by Krell et al. in @CellReports.

Beta cells intrinsically sense and limit their secretory activity via mTORC1-RhoA signaling: Cell Reports www.cell.com/cell-reports...
Beta cells intrinsically sense and limit their secretory activity via mTORC1-RhoA signaling
Krell et al. show that mTORC1 in β cells acts as an activity sensor, activated by the same signals that trigger insulin secretion. This activation, in turn, inhibits insulin release via RhoA-dependent...
www.cell.com
5 15