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Reposted by Russell Cox Chem

Marc Stadler @ms-fungi.bsky.social · 11h

mycokeys.pensoft.net/article/1604...
Finally Yok's last paper from her successful PhD thesis where she worked at #Mae Fah Luang University and with us at #HZI (among others) on Thai Earthballs is also out. It was just published by #Mycokeys. Congrats to all co-authors & thanks for funding from RRI!

Three new species and one new record of Scleroderma (Sclerodermataceae, Boletales) from northern Thailand

The genus Scleroderma (Sclerodermataceae) contains gasteroid ectomycorrhizal fungi and is distributed worldwide in temperate and tropical regions. Fresh specimens were collected in Thailand and report...

mycokeys.pensoft.net

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Reposted by Russell Cox Chem

Alex Speed @awhspeed.bsky.social · 5d

Is it correct to say an imine is "enolizable" if it has alpha protons? I guess an aza-enolate is a thing, so it seems fine to me to say that.

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Russell Cox Chem @russellcoxchem.bsky.social · 5d

Enaminable?

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Mitja M. Zdouc @mmzdouc.bsky.social · 11d

Aaand it's out! Meet MITE - the natural product tailoring enzyme database, just published in @narjournal.bsky.social! MITE DB captures the substrate- and reaction-specificity of tailoring enzymes, allowing to capture this information in a human- and machine-readable way! doi.org/10.1093/nar/...

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Royal Society of Chemistry @rsc.org · Sep 2

Great science matters. These articles in core subjects from analytical to energy chemistry shaped their discipline last year – read our curated collections and gather insights to fuel your own work.
URL ➡️ https://rsc.li/47nqzZt
#ChemSky

Promotional banner for RSC Advances showing blue microscopic cells with text overlay highlighting 'Year in review: A-E - This is high impact research from 2024. Read now.'

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Matt Hutchings @matthutchings.bsky.social · Aug 12

A new bench at JIC in memory of Helen Kieser. She moved to Norwich with David Hopwood in the 1960s and was instrumental in establishing the Streptomyces group and Molecular Microbiology @johninnescentre.bsky.social. Hard to overstate her importance to the #streptomyces field and community.

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Russell Cox Chem @russellcoxchem.bsky.social · Aug 28

How do iterative PKS make EZE trienes using a single DH domain? See the results of our experiments on ChemRxiv at:

Stereochemical Dissection of the Strobilurin PKS Reveals the Complex Biosynthetic Logic of Iterative EZE Triene Construction | ChemRxiv - doi.org/10.26434/che...

Stereochemical Dissection of the Strobilurin PKS Reveals the Complex Biosynthetic Logic of Iterative EZE Triene Construction

Type I Iterative polyketide synthases (PKS) use a limited set of catalytic extension and -processing domains to create complex polyketides. A remarkable case is that of the strobilurin PKS where a sin...

doi.org

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Mitja M. Zdouc @mmzdouc.bsky.social · Aug 21

Into natural product biosynthesis & tailoring enzymes? Frustrated by the lack of a dedicated resource to explore their functions? Tired of endless literature searches for reaction info? Meet the MITE database, freely available at mite.bioinformatics.nl. Preprint: doi.org/10.26434/che... (1/8)

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Marc Stadler @ms-fungi.bsky.social · Aug 9

pubs.rsc.org/en/content/a...
Our new review on the secondary metabolites of coprophilous fungi has just been published by Natural Product Reports. Thanks for funding from the @humboldt-foundation.de foundation.de, the @dfg.de & the @daadworldwide.bsky.social Congrats to all coauthors!

Coprophilous fungi in the search for new antimicrobials and other beneficial natural products

Covering: up to 2025Microbial interactions involve complex processes shaped by their ecological contexts. Herbivore animal dung denotes an interesting ecological niche for the study of interorganism c...

pubs.rsc.org

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Russell Cox Chem @russellcoxchem.bsky.social · Aug 7

I like “mordant and explicit envelope-pushing”….

www.theguardian.com/film/2025/au...

‘Aggressively provocative’: first screening of Saltburn director’s Wuthering Heights gets mixed reaction

An early test showing of the forthcoming Brontë adaptation starring Margot Robbie and Jacob Elordi reveals film features horse rein sex, suggestive egg yolks and necrophile nuns

www.theguardian.com

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Nick Greeves @nickgreeves.bsky.social · Jul 30

Is it really appropriate for Nature to display such crude representations of organic molecules in articles?

#chemsky
www.nature.com/articles/d41...

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Russell Cox Chem @russellcoxchem.bsky.social · Jul 22

A new fluorescent amino acid, built into an unprecedented cytochalasan that possesses potent bioactivity…. See our latest work at pubs.rsc.org/en/content/a...

Synthesis of L-β-(6-azulenyl)alanine and the fluorescent actin disruptor (6-azuleno)chalasin H

l-β-(6-Azulenyl)alanine was synthesised for the first time. Supplementation of this compound to Pyricularia grisea ΔpyiA led to the biosynthesis of the unnatural (6-azuleno)chalasin H and its 1′-bromo...

pubs.rsc.org

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RSC Advances @rscadvances.rsc.org · Jul 21

We are delighted to celebrate our RSC Advances Editorial Board member Professor Young-Shin Jun, who was recognised as one of the 2025 distinguished women in chemistry and chemical engineering at the IUPAC meeting 🏆

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Maite Colinas @maitecolinas.bsky.social · Jul 16

Next one out from @oconnorlab.bsky.social department in @natchembio.nature.com. Work led by my office mate Allwin McDonald on the epimerisation of monoterpenoid indole alkaloids in Kratom!
#PlantSci
#NatProd

rdcu.be/ewvtP

Enzymatic epimerization of monoterpene indole alkaloids in kratom

Nature Chemical Biology - Monoterpene indole alkaloids are formed via a 3S stereoselective condensation between secologanin and tryptamine. Here the authors uncover the mechanism of epimerization...

rdcu.be

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Russell Cox Chem @russellcoxchem.bsky.social · Jul 16

Is there a significant difference between ‚for profit‘ journals where reviewers get very little benefit, and society journals where the scientific community is supported from the profits of publication and the review effort?

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Microbes.Info @microbesinfo.bsky.social · Jul 14

#Fungi related to species that hijack #brains of #insects ...

| #Ophiocordyceps | #infection | #Thailand | Via @sciencex.bsky.social

The cordyceps species in "The Last of Us," Ophiocordyceps unilateralis, is real and does exactly what the show purports —just not in humans, according to medical experts.

phys.org

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German Society for Plant Sciences (DBG) @plantsciencedbg.bsky.social · Jul 14

Withanolide #biosynthesis from nightshade plants decoded. Withanolide steroids are used as a basis for medications for centuries.

Now published by a team around @frankelab.bsky.social + @puckerlab.bsky.social in @natcomms.nature.com (DOI: 10.1038/s41467-025-61686-1).

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Russell Cox Chem @russellcoxchem.bsky.social · Jul 13

You don‘t have to review or read all of them… but where-ever possible you should select a society publisher!

www.theguardian.com/science/2025...

Quality of scientific papers questioned as academics ‘overwhelmed’ by the millions published

Widespread mockery of AI-generated rat with giant penis in one paper brings problem to public attention

www.theguardian.com

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Chenxin Li, PhD @chenxinli2.bsky.social · Jul 10

#PlantScience #SecMet

FrankeLab @frankelab.bsky.social · Jul 10

Extremely happy to see our withanolide biosynthesis paper out in @natcomms.nature.com‬ rdcu.be/evHOF
Fantastic team effort with the Pucker group @bpucker.bsky.social‬ @puckerlab.bsky.social‬ at @unibonn.bsky.social and Heretsch, Herde and Witte groups at @unihannover.bsky.social. Funded by @dfg.de

Phylogenomics and metabolic engineering reveal a conserved gene cluster in Solanaceae plants for withanolide biosynthesis

Nature Communications - Withanolides are plant steroids with potent bioactivities found in many medicinal plants including Withania somnifera, but their biosynthetic pathway is largely unknown....

rdcu.be

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FrankeLab @frankelab.bsky.social · Jun 11

Also check out my News & Views article for more details on the significance of this work 👇
rdcu.be/eqwOy

Biochemical breakthrough paves way to reliable supply of anticancer drug | Nature

‘Missing’ genes needed for the biosynthesis of a natural anticancer drug have been discovered by perturbing and analysing individual cells of yew trees. ‘Missing’ genes needed for the biosynthesis of a natural anticancer drug have been discovered by perturbing and analysing individual cells of yew trees.

rdcu.be

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FrankeLab @frankelab.bsky.social · Jun 11

Fantastic work by the Sattely group on taxol biosynthesis, featuring a highly innovative application of single nuclei sequencing to find elusive biosynthetic genes 👏
www.nature.com/articles/s41...

Discovery of FoTO1 and Taxol genes enables biosynthesis of baccatin III - Nature

An approach that combines single-nucleus RNA sequencing and multiplexed perturbation identifies genes that enable the biosynthesis of direct precursors of the anti-cancer drug Taxol, whose curren...

www.nature.com

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Reposted by Russell Cox Chem

Philipp Klahn @docklahn.bsky.social · May 11

Our work on "Synthesis and evaluation of pseudoglucosinolates (psGSLs) releasing isothiocyanates (ITCs) in the presence of azoreductases" found a new homw at ChemBioChem chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/... #chembio #chemsky @omc-gu.bsky.social @naturvetenskap.bsky.social