We are currently recruiting for two post-doc positions in the Lichman lab that require similar skills and experience. We aim to do a joint recruitment process with a single interview. If you apply...

Stellenausschreibungen in der Botanik und den Pflanzenwissenschaften

We are excited to launch a naming competition inspired by the recent preprint "Phylogenetic distance and structural diversity directing a reclassification of glycopeptide antibiotics" (https://www.bio...

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Nature Communications - Withanolides are plant steroids with potent bioactivities found in many medicinal plants including Withania somnifera, but their biosynthetic pathway is largely unknown....

Paclitaxel (sold as Taxol) is taxane diterpene natural product of yew trees (Taxus spp.) and a potent stabilizer of microtubules that is effective in treatment of cancers. However…

‘Missing’ genes needed for the biosynthesis of a natural anticancer drug have been discovered by perturbing and analysing individual cells of yew trees. ‘Missing’ genes needed for the biosynthesis of a natural anticancer drug have been discovered by perturbing and analysing individual cells of yew trees.

An approach that combines single-nucleus RNA sequencing and multiplexed perturbation identifies genes that enable the biosynthesis of direct precursors of the anti-cancer drug Taxol, whose curren...

Triterpenoids and steroids are structurally complex polycyclic natural products with potent biological functions, for example, as hormones. In all eukaryotes, the carbon skeletons of these compounds a...

Decades of research on the infamous antinutritional steroidal glycoalkaloids (SGAs) in Solanaceae plants have provided deep insights into their metabolism and roles. However, engineering SGAs in heter...