sandimmunology.bsky.social
@sandimmunology.bsky.social
Reposted
📚NEW #gdTcell PAPER ALERT! Dysregulation of γδ intraepithelial lymphocytes precedes Crohn’s disease–like ileitis | Science Immunology
Bluetorial coming soon!!! #gastrosky #GIsky #IBDsky @nbgolovchenko.bsky.social @squeakyanimal.bsky.social @andrewfong.bsky.social
Dysregulation of γδ intraepithelial lymphocytes precedes Crohn’s disease–like ileitis
Multiple layers of γδ IEL dysregulation and loss of their immunosuppressive capacity occur before the onset of chronic ileitis.
www.science.org
March 21, 2025 at 6:14 PM
Reposted
Tools
"Here, we present parallel-flow projection and transfer learning across omics data (PLATO), an integrated framework combining microfluidics with deep learning to enable high-resolution mapping of thousands of proteins in whole tissue sections."
www.cell.com/cell/fulltex...
High-resolution spatially resolved proteomics of complex tissues based on microfluidics and transfer learning
PLATO, a high-resolution and high-throughput spatial mass spectrometry proteomics platform, identifies distinct tumor subtypes and key dysregulated proteins in human breast cancer.
www.cell.com
January 27, 2025 at 1:08 AM
Reposted
That moment when you remember that you are one of the few vertebrates that don't have #gdTcells.
January 25, 2025 at 12:14 PM
Yesterday, Paul Kubes gave an outstanding lecture at our institute @unibern.bsky.social . It was refreshing to see research where, for once, the microbiota did not take center stage. Congratulations to the talented scientists behind this impressive work, now published in Science Immunology.
January 14, 2025 at 9:18 AM