Sarah Guest
@sarahmoeba.bsky.social
170 followers 290 following 24 posts
Postdoc in the Fritz-Laylin lab, fascinated by obscure protists. Evolutionary Cell Bio research on amoebae & cytoskeleton. Sometimes art. she/her.
Posts Media Videos Starter Packs
Reposted by Sarah Guest
burnsajohn.bsky.social
This is glorious! And diatoms are as weird as ever!
floravincent.bsky.social
Excited to share the lab's 1rst preprint! Rapid high-res immunofluorescence is now possible in cultured & environmental diatoms thanks to 4-fold expansion microscopy. A step-change for comparative cell biology in one of the most important phytoplankton groups on the planet 🥳
tinyurl.com/m9s5su7s 1/2
Reposted by Sarah Guest
strassert.bsky.social
Happy to have contributed to this great article: #Protist genomics: key to understanding eukaryotic evolution. Congrats Alexandra Schoenle et al. #ProtistsOnSky
authors.elsevier.com/sd/article/S...
Reposted by Sarah Guest
jeukmicro.bsky.social
Highlighted paper! Daisuke Yamagishi, et al. open a new front in the drive to understand photosymbiosis in protists.

Article➡️ doi.org/10.1111/jeu....

#protistsonsky
sarahmoeba.bsky.social
Synopsis: A hungry amoeba attempts to eat another amoeba roughly equal to its own size. After numerous failed attempts to engulf it, and briefly losing it in a mess of detritus, it encounters a flailing nematode. Fearing for its life, it abandons its prey, and finally captures a smaller meal.
sarahmoeba.bsky.social
An amoeba movie I made: "hungry" #protistsonsky #amoeba
Reposted by Sarah Guest
blarson.bsky.social
I contributed an essay and some images to the new Living Futures series, an outgrowth of the fantastic Living Histories series organized by Sri Biswas and others.
medium.com/@thelhseries...

iyerbiswas.com/outreach/liv...

1/3
Microbial Marvels, Microscopes, Math, and Mentorship
by Ben Larson for Living Futures
medium.com
sarahmoeba.bsky.social
Poor dude can't catch dinner #protistsonsky #amoeba
Reposted by Sarah Guest
petergleick.bsky.social
There are 2 previous historical cases of countries destroying their science and universities, crippling them for decades: Lysenkoism in the USSR and Nazi Germany. The Trump administration will be the 3rd.
It's not just budgets but research, institutions, expertise, and training the next generation.
Graphs showing 25 years of budgets for the National Institute of Health, NASA, and the NSF. In all cases, the proposed budget for next year is far, far below any year of the previous quarter century.
sarahmoeba.bsky.social
Another bog friend #protistsonsky
Reposted by Sarah Guest
burnsajohn.bsky.social
The inside of our net was coated with these tiny jelly balls. I asked @blancobercial.bsky.social if they were some kind of ctenophore, but he said (enthusiastically) "No! These are #Rhizaria!" He is holding a single cell here. #marinelife #protistsonsky
Reposted by Sarah Guest
dumack.bsky.social
Evidence for #recombination, and maybe #meiosis, in free-living #Rhizaria! I wish the results were clearer. As so often we raised more questions than we could answer :) If you are into #sex and the #meiosis-toolkit, this is an important read! #ProtistsOnSky link.springer.com/article/10.1...
Reposted by Sarah Guest
dictyostelium.bsky.social
New paper out in @pnas.org

We followed cells migrating along signalling gradients in 3D, and found they collectively behave as a living droplet - a self-propelling fluid that grows.

www.pnas.org/doi/10.1073/...
Reposted by Sarah Guest
biorxivpreprint.bsky.social
Myosin 2 drives actin contractility in fast-crawling species outside of the amorphean lineage https://www.biorxiv.org/content/10.1101/2025.05.16.654244v1
sarahmoeba.bsky.social
A quick craft project: hand-cut phase annuli from construction paper to fit an "adopted" microscope that was missing ph1 ph2 and ph3
sarahmoeba.bsky.social
I thought internal flagella was a characteristic of ALL spirochetes, not just Borrelia?
sarahmoeba.bsky.social
Also yes. Glad to know someone else is aware of their lovely microtubule arrays!
sarahmoeba.bsky.social
There were also several heliozoans resembling Raphidocystis pallida, with clustered spindle-shaped scales among their axopodia! I'll add another picture today if I get a chance.
sarahmoeba.bsky.social
Yes, I was very excited to find this individual and several others in the sample. It's always fun to find a non-Amoebozoan amoeba! The SAR are near and dear to my heart as well.
sarahmoeba.bsky.social
It's hard to see from the image, but at this stage there were some vacuoules and clear cytoplasm inside the new shell, just none of the cell's larger and pigmented organelles
sarahmoeba.bsky.social
Yes, from what I saw at the start, and from this observation (below), the new shell is secreted first from the opening and assembled from within arcella.nl/lesquereusia...
Lesquereusia spiralis – division – Microworld
arcella.nl
sarahmoeba.bsky.social
Yes, I agree! Especially long hours at the microscope too, when your cells are a bit slower than the charismatic Lacrymaria. Amoebae tend to need to be a bit sped-up in post!
sarahmoeba.bsky.social
I knew I had to stick around to watch the process!
sarahmoeba.bsky.social
Acanthocystis (maybe?) from the same bog sample. Sometimes amoebae don't need phase contrast, especially if they're full of zoochlorellae/plastids! #protistsonsky #bogblog