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SFB1361 @sfb1361.bsky.social · 1d

It is with deep sadness that we share the news of the unexpected passing of our dear colleague and associated member Dr Nard Kubben last week.

We extend our heartfelt condolences to his family, friends, and all those who had the privilege of knowing him.

Institute of Molecular Biology (IMB) @imbmainz.bsky.social · 2d

We are deeply saddened to announce the unexpected passing of our colleague Dr Nard Kubben. He joined IMB as a Group Leader in 2021, bringing a passion for understanding ageing & improving human health. Our heartfelt condolences go to his family, friends & all who knew him.
www.imb.de/about-imb/ne...

SFB1361 @sfb1361.bsky.social · 1d

Publication alert!!📑

Congratulations to the @hopfnerlab.bsky.social, @yilanfan.bsky.social and @filizkuybu.bsky.social on the great work!

Read about it here: www.nature.com/articles/s41...

Hopfner Lab @hopfnerlab.bsky.social · 20d

Thrilled that our work is now finally out in Nature Comms!
rdcu.be/eG3vP

We reveal cryo-EM structures of the MRN complex bound to DNA & TRF2 - showing how DNA breaks are sensed and regulated at telomeres.
Fantastic work by first authors @yilanfan.bsky.social @filizkuybu.bsky.social & Hengjun!

SFB1361 @sfb1361.bsky.social · 19d

Yesterday’s full-day workshop co-organised with @imbmainz.bsky.social focused on building a strategic approach to research funding for postdocs.

We’re proud to stand behind our postdocs as they shape the future of research!

#PAWde #PostdocAppreciationWeek2025 #IMBMainz

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SFB1361 @sfb1361.bsky.social · Sep 3

📃Just published: new #SFB1361 publication by the Krämer and Christmann labs!
The article focuses on how the deacetylases HDAC1/HDAC2 control JAK2V617F-STAT signaling through the ubiquitin ligase SIAH2.
Find out more here:
🔎 www.nature.com/articles/s41...

The deacetylases HDAC1/HDAC2 control JAK2V617F-STAT signaling through the ubiquitin ligase SIAH2 - Signal Transduction and Targeted Therapy

Signal Transduction and Targeted Therapy - The deacetylases HDAC1/HDAC2 control JAK2V617F-STAT signaling through the ubiquitin ligase SIAH2

www.nature.com

SFB1361 @sfb1361.bsky.social · Aug 15

We’re excited to welcome Susanne Gerber from the University Medical Center Mainz as an associated member of the #SFB1361! 🎉
Her expertise in bioinformatics and cutting-edge nanopore sequencing protocols will advance genomic and epigenomic research within our network.

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SFB1361 @sfb1361.bsky.social · Aug 7

We‘re proud to share that our #SFB1361 PhD student, Yilan Fan from the @hopfnerlab.bsky.social, has been awarded a poster prize at the CNIO-CaixaResearch Frontiers Meeting “Machines on DNA and RNA: A Molecular Mechanistic Perspective“ held on 28-30 May 2025 in Madrid, Spain.
Congrats! 🎉

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SFB1361 @sfb1361.bsky.social · Jun 24

Last week our #SFB1361 members gathered in Würzburg to discuss and plan for the 3rd funding period.

This 3-day retreat led to many fruitful discussions and fresh ideas! Now its time to put these ideas to work! 🔬⚗️🧬

#scientificretreat #planning #DNArepair

SFB1361 @sfb1361.bsky.social · Jun 23

The 2nd Life Sciences Postdoc Symposium in Mainz is happening this week! Registration is still open!

www.imb.de/seminars-mee...

#postdoc #postdoclife

Institute of Molecular Biology (IMB) @imbmainz.bsky.social · May 13

2nd Life Sciences Postdoc Symposium Mainz - Connect, learn & grow with fellow postdocs & staff scientists from Mainz, Frankfurt, Darmstadt & the region! 🔬

26 June 2025
➡️ www.imb.de/postdoc-symposium25

Join us to strengthen your scientific network & exchange ideas with your peers.

#postdoclife

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SFB1361 @sfb1361.bsky.social · Jun 19

Our members came from Mainz, Frankfurt, Darmstadt, and Munich to Würzburg for this retreat to discuss, network, and plan for the next years.
We also took the opportunity to visit the Würzburg Residence and immerse ourselves in the art, culture, and history!

#würzburg #SFB1361 #retreat

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SFB1361 @sfb1361.bsky.social · Jun 17

Poster presentations, discussions, and networking.
Of course, our PhDs and Postdocs are also very much involved in this retreat.

#SFB1361 #DNArepair #scientificretreat

SFB1361 @sfb1361.bsky.social · Jun 16

Our #SFB1361 is away on #retreat from today until Wednesday!

Starting off the day with most of us travelling by train to Würzburg and plenty of project updates in the afternoon!

Excited to plan for the next years and the next funding period!

#ecofriendly #worktravel
#dnarepair

SFB1361 @sfb1361.bsky.social · May 23

Cheers to a successful #PintofScience in Mainz! 🎉🎉

We're proud to have supported this effort and that our associated member presented her science in an interesting way to the public! Also a round of applause to all other presenters 👏👏

#pint25de #sciencecommunication

SFB1361 @sfb1361.bsky.social · May 14

On next Wednesday (21 May), our associated member, Siyao Wang will talk on how the damage on the #DNA of fathers affects the children as part of the Pint of Science 2025 events!

Buy your tickets now! www.pintofscience.de/events/mainz

#pint25de 🥳

ChiaraG @chiaragaly.bsky.social · May 14

On Wednesday we'll also hear from Siyao how the damage on the #DNA of fathers affects the children.

Siyao is a junior group leader at @imbmainz.bsky.social and is looking forward to meeting you at the #pint25de 🥳

Buy your tickets now! www.pintofscience.de/events/mainz

#DNAdamage #MainzErleben

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SFB1361 @sfb1361.bsky.social · May 13

Are you interested in what goes on in the minds of scientists in Mainz? Here's your chance to listen to exciting talks on physics, stress, genetics and more in a relaxed atmosphere and chat with the scientists.

Get your tickets now! www.pintofscience.de/events/mainz

#pint25de #Mainz #scicomm

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SFB1361 @sfb1361.bsky.social · May 9

(2/2) Participants looked at using tools for literature research, brainstorming, communication, strategising, and much more.

It was a pleasure to co-organise this with @imbmainz.bsky.social's Professional Development Office, @4r-rtg.bsky.social , GenEvo, SFB1552, and @sfb1551.bsky.social.

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SFB1361 @sfb1361.bsky.social · May 9

(1/2) Have you thought about using AI Assistants? How and where can these tools help us? Our researchers were surely excited to explore!

We jointly organised a 2-day workshop on "Using AI Assistants to Increase Productivity" to provide the initial stepping stones to use these tools.
#training #AI

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SFB1361 @sfb1361.bsky.social · Apr 28

Our RMU Master Module on DNA Repair & Genome Stability starts today with the first lecture from Prof Brian Luke!
#SFB1361 #DNArepair #RMU

SFB1361 @sfb1361.bsky.social · Mar 17

Pre-print alert from @hopfnerlab.bsky.social!

Great job! Read more about it here: www.biorxiv.org/content/10.1...

#DNArepair #SFB1361

Hopfner Lab @hopfnerlab.bsky.social · Mar 17

Happy to share our latest pre-print!
We solved the cryoEM structures of human DNA repair factor MRN bound to DNA and to TRF2. Main work of Yilan, Filiz @filizkuybu.bsky.social and Hengjun. Great collab within the @sfb1361.bsky.social and @genecenter-lmu.bsky.social 🧬🔨
www.biorxiv.org/content/10.1...

Structural basis for DNA double-strand break sensing by human MRE11-RAD50-NBS1 and its TRF2 complex

The MRE11-RAD50-NBS1 (MRN) complex is a central, multifunctional factor in the detection, signaling and nucleolytic processing of DNA double-strand breaks (DSBs). To clarify how human MRN binds generi...

www.biorxiv.org

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SFB1361 @sfb1361.bsky.social · Mar 12

(3/3) Thank you again to our 4 panellists who shared on their careers and a treasure trove of experiences: (from left to right) Katharina Papsdorf (IMB, Mainz), Beate Scheurer (ICON, Frankfurt), Miryam Müller (BioNTech, Mainz), and Jiska van der Reest (VIB, Ghent).

#IWD2025 @kpapsdorf.bsky.social

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SFB1361 @sfb1361.bsky.social · Mar 12

(2/3) Participants took part in a workshop entitled “Business with Attention” led by public speaking guru Katarina Kovalcikova (SpeakUP, Bratislava) and a career panel with panellists bringing vast experiences from diverse professions and backgrounds.

#IWD2025 @imbmainz.bsky.social

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SFB1361 @sfb1361.bsky.social · Mar 12

(1/3) In conjunction with International Women’s Day, we organised a day of training and experience sharing tailored for our fantastic female PhDs and Postdocs.

It was a pleasure to co-organise this event with @4r-rtg.bsky.social, GenEvo, and @sfb1551.bsky.social.

#IWD2025 #Workshop #CareerPanel

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SFB1361 @sfb1361.bsky.social · Mar 10

Publication alert! An interesting review on RNA damage coming from the lab of @jstingele.bsky.social!

Read the review here: www.cell.com/cell/fulltex...

Read an interview on the article from @lmumuenchen.bsky.social (LMU Munich) here: www.lmu.de/en/newsroom/...

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SFB1361 @sfb1361.bsky.social · Mar 8

Happy International Women's Day!

Today we celebrate the achievement of women everywhere and the progress made towards equality! Let's stay committed on this path and #AccelerateAction towards #genderequality!

#IWD2025 #InternationalWomensDay

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SFB1361 @sfb1361.bsky.social · Mar 7

Less than a month left to apply to the International PhD programme!

Looking to develop a scientific career in #DNArepair, #RNAbiology, #Bioinformatics, or #Immunology? Apply now join our global community of over 200 #PhD students! 🌍

Institute of Molecular Biology (IMB) @imbmainz.bsky.social · Feb 17

The summer call of our International PhD programme is open! 📢

Ready to advance your scientific career? If you're passionate about #RNAbiology, #Bioinformatics, or #Immunology, apply to our open calls and join our global community of over 200 #PhD students! 🌍

www.imb.de/phd

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SFB1361 @sfb1361.bsky.social · Feb 27

📢 Save the Date! - Join us for the IMB & SFB 1361 Conference – The Evil Within: Regulation and Repair of Endogenous DNA Damage!

📅 Date: 10-13 March 2026

More infos via www.sfb1361.de/dnarepairconf2026

Institute of Molecular Biology (IMB) @imbmainz.bsky.social · Feb 27

📢 Save the Date! - Join us for the IMB & SFB 1361 Conference – The Evil Within: Regulation and Repair of Endogenous DNA Damage!

📅 Date: 10-13 March 2026

More infos via www.sfb1361.de/dnarepairconf2026
@sfb1361.bsky.social

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