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Nitzan Shabek

@shabeklab.bsky.social

940 followers 960 following 5 posts

Prof. @UC Davis ∙structural biologist⚛︎ ubiquitin system aficionado ✾ signaling & sensing mechanisms in plants🌱in vivo interacomes 🎸dad of 2 https://shabek-lab.ucdavis.edu/

shabek-lab.ucdavis.edu

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Nitzan Shabek @shabeklab.bsky.social · Nov 16

our latest work @natureportfolio.bsky.social nature communications: Structural insights into strigolactone catabolism by carboxylesterases reveal a conserved conformational regulation
rdcu.be/d0s6l

Structural insights into strigolactone catabolism by carboxylesterases reveal a conserved conformational regulation

Nature Communications - Plant hormone levels are regulated by synthesis and breakdown, but the mechanism of strigolactone degradation remains unclear. This study reveals the structure of distinct...

rdcu.be

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Nitzan Shabek @shabeklab.bsky.social · May 19

excited to be part of this study published @pnas.org led by the wonderful Caroline Gutjahr 👏revealing how the GRAS protein RAM1 partners with WRI transcription factors to regulate genes essential for arbuscule formation & nutrient exchange in plant-fungal symbiosis www.pnas.org/doi/10.1073/...

PNAS

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

www.pnas.org

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Reposted by Nitzan Shabek

Suayb Üstün @suaybuestuen.bsky.social · Mar 5

Wow! The Proteasome generates antimicrobial peptides that directly affect bacterial membranes #proteostasis
www.nature.com/articles/s41...

Cell-autonomous innate immunity by proteasome-derived defence peptides - Nature

Proteasomal degradation of cellular proteins generate defence peptides constitutively and in response to bacterial infection. Such peptides might provide a source of natural antibiotics that...

www.nature.com

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Reposted by Nitzan Shabek

Karolin Luger @nucleosomepolice.bsky.social · Mar 1

🧪what with the demolition of #NIH funded #research, where, dare I ask, are our friends from #bigpharma? y'all good? mooched enough off of public-access NIH-funded research? Stocked up with PhD level scientists who were trained on NIH training grants to tide you over until Academia comes back?

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Nitzan Shabek @shabeklab.bsky.social · Jan 18

Super excited to contribute to this amazing work on the evolution of interorganismal strigolactone biosynthesis
www.science.org/doi/10.1126/...

Evolution of interorganismal strigolactone biosynthesis in seed plants

Strigolactones (SLs) are methylbutenolide molecules derived from β-carotene through an intermediate carlactonoic acid (CLA). Canonical SLs act as signals to microbes and plants, whereas noncanonical S...

www.science.org

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Reposted by Nitzan Shabek

Rashmi Agrata @rashmiagrata.bsky.social · Jan 17

New to #ubiquitin? Been with it for a while? Either way this review may be for you 🤩

Excited to share our review article in @molcell.bsky.social, diving deep into everything #ubiquitin
Read here 👉: kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...

@cellpress.bsky.social
@wehi-research.bsky.social

'Ubiquitin Lysine-Linkages' from the review 'Ubiquitin: a structural perspective' in Molecular Cell

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Reposted by Nitzan Shabek

New Phytologist @newphyt.bsky.social · Nov 21

🆕 Our Latest Issue is online now!

📚 nph.onlinelibrary.wiley.com/toc/14698137...

Highlights:
🌱 Announcing the 2024 Tansley Medal winner
🌱 Unravelling plant centromeres
🌱 Is auxin the key to improve crop nitrogen efficiency?
🌱 Vegetation responses to moisture conditions

New Phytologist: Vol 244, No 6

<em>New Phytologist</em> is an international journal owned by the New Phytologist Foundation publishing original research in plant science and its applications.

nph.onlinelibrary.wiley.com

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Nitzan Shabek @shabeklab.bsky.social · Nov 21

Excited to share that our research on the SCF E3 ubiquitin ligase interactome in plants is now published in New Phytologist and featured as the cover of the current issue! 🌱 @newphyt.bsky.social #ubiquitin #proteostasis
nph.onlinelibrary.wiley.com/share/CA8XRQ...

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Reposted by Nitzan Shabek

Suayb Üstün @suaybuestuen.bsky.social · Nov 20

I made a starter pack for the plant proteostasis community - please let me know if I missed someone to add new members #proteostasis

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Reposted by Nitzan Shabek

2025 International Plant Growth Substance Association (IPGSA) @ipgsa2025.bsky.social · Nov 20

The email announcement of International Plant Growth Substances Association (IPGSA) Conference in 2025 in Fort Collins, Colorado, USA is just out! Please spread the word of what will be a very exciting conference in a beautiful place. #IPGSA2025

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Reposted by Nitzan Shabek

Justin Walley @justinwwalley.bsky.social · Nov 10

Final version of or single-cell proteomics paper is now published in the New Phytologist December issue! @dormichicken.bsky.social
nph.onlinelibrary.wiley.com/doi/10.1111/...

Single‐cell proteomics differentiates Arabidopsis root cell types

nph.onlinelibrary.wiley.com

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Reposted by Nitzan Shabek

Nitzan Shabek @shabeklab.bsky.social · Nov 16

our latest work @natureportfolio.bsky.social nature communications: Structural insights into strigolactone catabolism by carboxylesterases reveal a conserved conformational regulation
rdcu.be/d0s6l

Structural insights into strigolactone catabolism by carboxylesterases reveal a conserved conformational regulation

Nature Communications - Plant hormone levels are regulated by synthesis and breakdown, but the mechanism of strigolactone degradation remains unclear. This study reveals the structure of distinct...

rdcu.be

5 26

Reposted by Nitzan Shabek

Jens Hör @jenshoer.bsky.social · Nov 11

Should've done this a long time ago, but here's my first post on #Bluesky.

Check out my postdoc paper on a bacterial ubiquitin-like defense system that we recently published!

www.nature.com/articles/s41...

Bacteria conjugate ubiquitin-like proteins to interfere with phage assembly - Nature

To mitigate phage infection, an antiphage defence system in bacteria conjugates a ubiquitin-like protein to a structural protein of the phage, demonstrating that conjugation of ubiquiti...

www.nature.com

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Reposted by Nitzan Shabek

Rune Busk Damgaard @rbdamgaard.bsky.social · Nov 15

Check out this list of ubiquitin and Ubl profiles to follow. Repost if you want me to add you to it. Let’s create a good community here ☁️ go.bsky.app/3VPQofn

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Reposted by Nitzan Shabek

Denneal Jamison-McClung @dsjamison.bsky.social · Nov 14

I direct the UC Davis Biotechnology Program - looking forward to building #academicsky community! 🧬🧫🔬🧪🥼#ucdavis #biotech

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Nitzan Shabek @shabeklab.bsky.social · Nov 16

our latest work @natureportfolio.bsky.social nature communications: Structural insights into strigolactone catabolism by carboxylesterases reveal a conserved conformational regulation
rdcu.be/d0s6l

Structural insights into strigolactone catabolism by carboxylesterases reveal a conserved conformational regulation

Nature Communications - Plant hormone levels are regulated by synthesis and breakdown, but the mechanism of strigolactone degradation remains unclear. This study reveals the structure of distinct...

rdcu.be

5 26

Nitzan Shabek @shabeklab.bsky.social · Nov 16

molecular basis of SCOOP perception by the MIK2–BAK1 immune complex rdcu.be/d0s5E

Mechanistic study of SCOOPs recognition by MIK2–BAK1 complex reveals the role of N-glycans in plant ligand–receptor–coreceptor complex formation

Nature Plants - Wu et al. elucidate the molecular basis for SCOOPs perception by the MIK2–BAK1 immune complex and demonstrate an unexpectedly pivotal role of N-glycans in plant...

rdcu.be