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Dana Shaw

@shawlab.bsky.social

920 followers 410 following 28 posts

Associate Professor at WSU studying how and why ticks transmit disease 🦠🕷🩸🧬🧫 www.shawlab.org

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Dana Shaw @shawlab.bsky.social · Jun 17

Thrilled to see this out in PNAS today!!🎉 Big congratulations to graduate student @kaylee-vosbigian.bsky.social on her first, first-author paper!

www.pnas.org/doi/10.1073/...

Reposted by Dana Shaw

Anya O’Neal @anyaoneal.bsky.social · 10h

We’re also hiring a Research Tech: jobs.jhu.edu/job-invite/1...

Research Technologist (Molecular Microbiology & Immunology)

Research Technologist (Molecular Microbiology & Immunology)

Reposted by Dana Shaw

Anya O’Neal @anyaoneal.bsky.social · 6d

The O'Neal Lab in @johnshopkinssph.bsky.social is hiring a Lab Manager to work on ticks and tick-borne diseases! You can apply here: jobs.jhu.edu/job-invite/1...

Laboratory Manager (Molecular Microbiology & Immunology)

Laboratory Manager (Molecular Microbiology & Immunology)

Dana Shaw @shawlab.bsky.social · 14d

💯 These guys are fascinating - I could watch them swim around all day!

Dana Shaw @shawlab.bsky.social · 14d

Check these guys out! #MicroSky #LymeDisease

Baylink Lab @baylinklab.bsky.social · 15d

You’ve heard of #Lymedisease, but have you ever seen the bacteria that causes it? 🦠 Borrelia burgdorferi, the spiral-shaped culprit transmitted by ticks, swims with a creepy wriggling motion and uses #chemotaxis to navigate. Both fascinating... and disgusting #Microsky 🧪 #IDsky @shawlab.bsky.social

Dana Shaw @shawlab.bsky.social · Sep 4

These results indicate that ATR could impact Ixodes population dynamics, prevalence of infected ticks, and pathogen circulation in the wild!

Dana Shaw @shawlab.bsky.social · Sep 4

When challenged with Borrelia or Anaplasma, larvae fed on sensitized mice ingested more bacteria. Notably, although sex did not impact larval feeding success, it did influence pathogen load in the tick, suggesting that undefined variables between male and female mice influence transmission dynamics.

Dana Shaw @shawlab.bsky.social · Sep 4

Ticks fed on sensitized mice ingested more host leukocytes when compared to those fed on naïve hosts, which rarely ingested nucleated cells.

Dana Shaw @shawlab.bsky.social · Sep 4

…with an influx of basophils, eosinophils, neutrophils, and T lymphocytes

Dana Shaw @shawlab.bsky.social · Sep 4

Mice exhibited increasingly severe inflammation at tick bite sites...

Dana Shaw @shawlab.bsky.social · Sep 4

Repeated I. scapularis larval infestations on P. leucopus lead to reduced feeding success (over 50%) and decreased blood meal weight.

Dana Shaw @shawlab.bsky.social · Sep 4

Happy to share the latest pub from our lab!

journals.asm.org/doi/10.1128/...

We found that reservoir host species, Peromyscus leucopus, develop acquired tick resistance against larval Ixodes scapularis, which reduces tick feeding success and affects pathogen ingestion by larvae.

Acquired tick resistance in Peromyscus leucopus alters Ixodes scapularis infection | Infection and Immunity

The incidence of tick-borne disease in the United States has been on the rise over the last decade, with 50,865 cases reported in 2019 increasing to 73,384 cases in 2022 (1). However, passive surveill...

journals.asm.org

Dana Shaw @shawlab.bsky.social · Aug 21

Check out the latest Nature Microbiology Journal Club article written by Cameron Coyle spotlighting the diverse roles that tick haemocytes have in arthropod immunity and fitness!

This piece highlights @rolandelliagus.bsky.social and Joao Pedra’s work, linked here: www.nature.com/articles/s41...

Nature Microbiology @natmicrobiol.nature.com · Aug 21

#JournalClub

An atlas for tick immune cells

#MicroSky

www.nature.com/articles/s41...

An atlas for tick immune cells - Nature Microbiology

Nature Microbiology - An atlas for tick immune cells

Dana Shaw @shawlab.bsky.social · Aug 11

Sunday funday 🤩 🚲 🏊🏻‍♀️

Reposted by Dana Shaw

Harmit Singh Malik @harmitmalik.bsky.social · Jul 31

NIH wants to hear from you. No really.

Request for Information on Maximizing Research Funds by Limiting Allowable Publishing Costs
grants.nih.gov/grants/guide...

NOT-OD-25-138: Request for Information on Maximizing Research Funds by Limiting Allowable Publishing Costs

NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Request for Information on Maximizing Research Funds by Limiting Allowable Publishing Costs NOT-OD-25-138. NIH

Reposted by Dana Shaw

Armando Rosario-Lebrón @rosariolebronentomology.com · Jun 30

University of Nebraska-Lincoln is hiring an Assistant Professor specializing in insect systematics. Opportunities like this are rare and valuable! (Not many jobs like this out there!) Spread the word to anyone who might be interested or benefit.
#entomology #science #sciencejobs #bugsky 🧪

Reposted by Dana Shaw

Science Blog @scienceblog.com · Jun 30

The Tiny Thieves Inside Every Tick Bite

Every summer, millions of Americans venture into tall grass and wooded trails, unknowingly walking into microscopic crime scenes. Inside the ticks waiting in that vegetation, bacteria are pulling off one of nature's most elegant heists—turning their hosts'…

The Tiny Thieves Inside Every Tick Bite

Every summer, millions of Americans venture into tall grass and wooded trails, unknowingly walking into microscopic crime scenes. Inside the ticks waiting in that vegetation, bacteria are pulling off one of nature's most elegant heists—turning their hosts' own cellular machinery into accomplices. New research reveals exactly how the microbes behind Lyme disease and anaplasmosis hijack tick biology to fuel their spread.

scienceblog.com

Dana Shaw @shawlab.bsky.social · Jun 17

Thrilled to see this out in PNAS today!!🎉 Big congratulations to graduate student @kaylee-vosbigian.bsky.social on her first, first-author paper!

www.pnas.org/doi/10.1073/...

Dana Shaw @shawlab.bsky.social · Jun 2

Pro-tips for this summer:

theonion.com/tips-for-pre...

Tips For Preventing And Treating Tick Bites

Summer is tick season. The Onion shares tips for protecting yourself from ticks and the diseases that they carry. Wear long sleeves and tall socks when volunteering at the local tick shelter. Hike in ...

Dana Shaw @shawlab.bsky.social · Apr 1

Spring evening on the Palouse with my best girl

Dana Shaw @shawlab.bsky.social · Mar 8

Repping the WSU CVM today at the Pullman science rally! #standupforscience

Dana Shaw @shawlab.bsky.social · Mar 7

Proud of this crew! #standupforscience #MicroSky

Dana Shaw @shawlab.bsky.social · Mar 7

#standupforscience #microsky

Baylink Lab @baylinklab.bsky.social · Mar 7

Wanted to highlight the incredible efforts by graduate student Siena Glenn in our lab in helping organize our local #standupforscience

www.youtube.com/watch?v=0dfY...

#MicroSky #Microbiology @shawlab.bsky.social

'Stand Up for Science' Pullman- Local Scientists join national march against federal budget cuts

YouTube video by Emily Schmalz

www.youtube.com

Reposted by Dana Shaw

Harmit Singh Malik @harmitmalik.bsky.social · Jan 28

If you have been affected by the fires in LA, or are concerned about your ability to keep precious Drosophila strains going during the latest funding crisis, we will host your strains as a backup. Please email me.

Please amplify. If you are also able to host fly strains, add your name as well.

Dana Shaw @shawlab.bsky.social · Jan 10

Given that lipid hijacking is common among arthropod-borne microbes, ATF6-mediated induction of Stomatin may be a mechanism that is exploited in many vector-pathogen relationships for the survival and persistence of transmissible microbes!

Dana Shaw @shawlab.bsky.social · Jan 10

Using ArthroQuest, we found that, in contrast to humans, the large majority of arthropods had positive hits in the promoter regions of Stomatin orthologs, suggesting that the ATF6-regulated nature of Stomatin may be a common feature among blood-feeding arthropods!