Angry Redhead
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sidherian.bsky.social
Angry Redhead
@sidherian.bsky.social
Aus GenX, cranky femme lesbian 🐈🫖🗾 80s New Wave music nerd. Clean air, N95 😷, Greens member.
#COVIDISNOTOVER #MASKFORYOURLIFE
No DMs.
Which reminded me of this paper. 
Pattern recognition served me very well in my career but there are times I wish it would switch off.
pmc.ncbi.nlm.nih.gov/articles/PMC...
Host Manipulation Mechanisms of SARS-CoV-2 - PMC
Viruses are the simplest of pathogens, but possess sophisticated molecular mechanisms to manipulate host behavior, frequently utilizing molecular mimicry. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been shown to bind to the ...
pmc.ncbi.nlm.nih.gov
November 15, 2025 at 12:28 AM
Interestingly, rather than simply blocking those signals, Toxoplasma gets its way by doing the exact opposite: Bowler and his team found that the parasite actually kickstarts the human inflammatory response, and proceeds to manipulate it according to its own needs. “
November 15, 2025 at 12:28 AM
Under normal circumstances, when cells in your body detect a parasite, a series of molecular signals will activate a protein called p38α, prompting it to move into the cells' nuclei. Here, it activates the genes that trigger an inflammatory response to eliminate the pathogen.
November 15, 2025 at 12:28 AM
And now scientists have figured out how.  
"The parasite rewires the host's inflammatory response," says Matthew Bowler from the European Molecular Biology Laboratory. "It completely subverts the chain reaction that would normally trigger our body's defences."
November 15, 2025 at 12:28 AM
There was new to me infor about how toxo impacts its host. “Toxoplasma has managed to keep body's immune response to it low enough to ensure that it can still thrive in its human hosts, but high enough that those who are infected can live a healthy life as one giant incubator.”
November 15, 2025 at 12:27 AM
She’s an Australian journalist.
November 14, 2025 at 10:16 AM
There’s also community survey & we did a guide with details, links, screenshots & prompts to help you share your lived experience of the new discriminatory barriers to accessing public venues & participating in public life (that others take for granted)
November 11, 2025 at 3:42 AM
#C0VIDisnotover #maskforyourlife #cleantheair

Aus Human Rights Commission calling for subs to Disability Discrimination Act review

@CleanerAirAU did a sub on how discriminatory it is that at risk Australians now lack safe access to participate in public life.
November 11, 2025 at 3:42 AM
Interrupting chain of transmission of IRD will optimize protection of 1st responders, paramedics, nurses, and doctors working in triage sites, emergency rooms, intensive care units, and the general public against cough-droplet-spread diseases.

bmcpublichealth.biomedcentral.com/articles/10....
Effectiveness of cough etiquette maneuvers in disrupting the chain of transmission of infectious respiratory diseases | BMC Public Health | Full Text
Background The effectiveness of recommended measures, such as “cover your mouth when coughing”, in disrupting the chain of transmission of infectious respiratory diseases (IRD) has been questioned. The objective of the current study was to determine the effectiveness of simple primary respiratory hygiene/cough etiquette maneuvers in blocking droplets expelled as aerosol during coughing. Method In this study, 31 healthy non-smokers performed cough etiquette maneuvers in an effort to cover their voluntarily elicited best effort coughs in an open bench format. A laser diffraction system was used to obtain accurate, non-invasive, quantitative, real time measurements of the size and number of droplets emitted during the assessed cough etiquette maneuvers. Results Recommended cough etiquette maneuvers did not block the release and dispersion of a variety of different diameter droplets to the surrounding environment. Droplets smaller than one-micron size dominate the total number of droplets leaked when practicing assessed maneuvers. Conclusions All the assessed cough etiquette maneuvers, performed as recommended, do not block droplets expelled as aerosol when coughing. This aerosol can penetrate profound levels of the respiratory system. Practicing these assessed primary respiratory hygiene/cough etiquette maneuvers would still permit direct, indirect, and/or airborne transmission and spread of IRD, such as influenza and Tuberculosis. All the assessed cough etiquette maneuvers, as recommended, do not fully interrupt the chain of transmission of IRD. This knowledge urges us all to critically review recommended CE and to search for new evidence-based procedures that effectively disrupt the transmission of respiratory pathogens. Interrupting the chain of transmission of IRD will optimize the protection of first responders, paramedics, nurses, and doctors working in triage sites, emergency rooms, intensive care units, and the general public against cough-droplet-spread diseases.
bmcpublichealth.biomedcentral.com
November 8, 2025 at 9:07 AM
All the assessed cough etiquette maneuvers, as recommended, do not fully interrupt the chain of transmission of IRD. This knowledge urges us all to critically review recommended CE and to search for new evidence-based procedures that effectively disrupt the transmission of respiratory pathogens.
November 8, 2025 at 9:07 AM
This aerosol can penetrate profound levels of the respiratory system. Practicing these assessed primary respiratory hygiene/cough etiquette maneuvers would still permit direct, indirect, and/or airborne transmission and spread of IRD, such as influenza and Tuberculosis.
November 8, 2025 at 9:07 AM
Droplets smaller than one-micron size dominate the total number of droplets leaked when practicing assessed maneuvers.

Conclusions   All the assessed cough etiquette maneuvers, performed as recommended, do not block droplets expelled as aerosol when coughing.
November 8, 2025 at 9:06 AM
Results Recommended cough etiquette maneuvers did not block the release and dispersion of a variety of different diameter droplets to the surrounding environment.
November 8, 2025 at 9:06 AM
A laser diffraction system was used to obtain accurate, non-invasive, quantitative, real time measurements of the size and number of droplets emitted during the assessed cough etiquette maneuvers.
November 8, 2025 at 9:06 AM
Method   In this study, 31 healthy non-smokers performed cough etiquette maneuvers in an effort to cover their voluntarily elicited best effort coughs in an open bench format.
November 8, 2025 at 9:06 AM
The objective of the current study was to determine the effectiveness of simple primary respiratory hygiene/cough etiquette maneuvers in blocking droplets expelled as aerosol during coughing.
November 8, 2025 at 9:06 AM
Background.                       The effectiveness of recommended measures “cover your mouth when coughing”, in disrupting chain of transmission of infectious respiratory diseases (IRD) has been questioned.
November 8, 2025 at 9:06 AM
Conclusion
Our results demonstrate a considerable burden of COVID-19-related persistent neurological signs/symptoms in children and adolescents, which should be taken into consideration in healthcare decision-making.
November 5, 2025 at 2:58 AM
Long-COVID-19-related neurological signs/symptoms were more common in the 11–16 age group. Children with immunocompetent profiles were at higher risk of developing long-COVID-19-related neurological signs/symptoms.
November 5, 2025 at 2:58 AM
The global prevalence of long COVID-19 neurological signs/symptoms was estimated between 0.4% (20/5032; 95% CI = 2.1–3%) and 34% (27/79) based on data obtained through online questionnaire; while it varied between 1.8% (4/215) and 83.14% (74/89; 95%CI =   −  0.12; 0.30) based on patient assessment.
November 5, 2025 at 2:58 AM
Results
The results of our analysis of 33 studies found long-COVID-19-related neurological signs/symptoms were predominantly: pain and sensory problems (N = 74,612/91,543; 81.5%), followed by sleep disturbances (N = 14,630/91,543; 15.9%), and cognitive difficulties (N = 2274/91,543; 2.4%).
November 5, 2025 at 2:58 AM