Every name on a list compiled by health authorities in Gaza of the child victims of Israel’s offensive

Nature Reviews Genetics, Published online: 16 September 2025; doi:10.1038/s41576-025-00880-9In this Comment, Wendy Bickmore discusses mechanistic models of how 3D genome organization facilitates communication between distant enhancers and their target promoters to regulate gene expression.

Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi have won the Nobel Prize in medicine for their discoveries about peripheral immune tolerance.

Nature Reviews Genetics, Published online: 30 September 2025; doi:10.1038/s41576-025-00892-5Spatial omics has empowered the discovery of developmental and disease-associated molecular signatures, cell states and multicellular niches, as well as the evaluation of disease heterogeneity within and across organs. The authors review spatially resolved molecular changes across diseases and discuss the potential of spatial multi-omics for clinical applications, including the recent impact of artificial intelligence.

Lateralization is a fundamental principle of structural brain organization. In vivo imaging of brain asymmetry is essential for deciphering lateralized brain functions and their disruption in neurodev...

Left-handers are better at some types of sports, but why? A new study investigated left-handers' advantage in sports from an interesting new perspective.

In this Review, Roden and co-workers describe how multiplexed assays of variant effects can be used for high-throughput functional assessment of nearly all coding variants in a target sequence to impr...

Disruption of the 3D genome caused by structural variation contributes to developmental disorders and cancer. The authors review the causes and molecular and clinical consequences of position effects ...

Impaired musical rhythm abilities and developmental speech-language related disorders are biologically and clinically intertwined. Here, the authors explore the correlation between the two traits, finding evidence of epidemiological associations and genetic overlap.

The tech giant blocked access after we revealed the Israeli army had been using its servers to store millions of Palestinians' intercepted phone calls.

Covering The Gaps

Italian Defence Minister Guido Crosetto strongly condemns overnight attack on an international flotilla trying to deliver aid to Gaza.