Lightnews — Scholar-powered news

Simon Beggs @simonbeggslab.bsky.social · 2d

"It also demonstrates the fairness of the prize, as Mary Brunkow is a Senior Program Manager (not a professor)". There's another way to interpret that.

2

Simon Beggs @simonbeggslab.bsky.social · 5d

by predominance, take away the care of knowing causes; which is a lust of the mind, that by a perseverance of delight in the continual and indefatigable generation of knowledge, exceedeth the short vehemence of any carnal pleasure."

Written by a man not encumbered by an editor's word limit.

1 2

Simon Beggs @simonbeggslab.bsky.social · 5d

Thomas Hobbes, Leviathan (1651): "Desire, to know why, and how, curiosity; such as is in no living creature but man: so that man is distinguished, not only by his reason; but also by this singular passion from other animals; in whom the appetite of food, and other pleasures of sense...

1 2

Simon Beggs @simonbeggslab.bsky.social · Sep 5

The PhD programmes won’t require a masters, but the competition is such that if you don’t have a masters and some relevant lab experience then your chances are slim.

4

Reposted by Simon Beggs

Kevin A Keay @kevinkeay.bsky.social · Aug 29

Somatotopic organization of brainstem analgesic circuitry | Science www.science.org/doi/10.1126/...

Somatotopic organization of brainstem analgesic circuitry

The lateral periaqueductal gray (lPAG) evokes somatotopically appropriate defensive behaviors, including an analgesia that allows the animal to escape or fight unimpeded. Whether the lPAG and its desc...

www.science.org

1 2 10

Reposted by Simon Beggs

Féaron Cassidy, PhD @fearoncassidy.bsky.social · Aug 27

Once you’ve done that, there is also a link in the thread to contact the lawyers who are filing the lawsuit with your details and details of your work.

1

Reposted by Simon Beggs

Protik Islam-Jakobsson @protik.bsky.social · Aug 23

First party to prioritize getting rid of Teams and SharePoint over screwing with immigrants will coast to landslide victories in national and EU elections

Protik Islam-Jakobsson @protik.bsky.social · Aug 23

For the EU, this should be a very urgent matter of national security. All EU member states should build on Denmark's wise strategy to phase out Microsoft products

2 8 56

Reposted by Simon Beggs

Liam Drew @liamdrew.bsky.social · Aug 6

Hi all, I’m going to be writing an article that looks at when in their careers scientists feel they do their most satisfying work… I’m sure it’ll vary hugely but if you’d like to help provide a starting point please fill in this survey - and please share! survey.alchemer.com/s3/8407348/C...

Careers survey - best work

survey.alchemer.com

4

Reposted by Simon Beggs

Ted Price @tedpricethepainguy.bsky.social · Jul 22

Our paper showing decreased KCC2 expression in the human spinal cord in people who died with a history of neuropathic pain is now published in PAIN: journals.lww.com/pain/abstrac... Great work from @oliviadavis.bsky.social and the teams of the De Koninck and Hildebrand labs. ❤️ 🇨🇦 collabs!

Decreased KCC2 expression in the human spinal dorsal horn... : PAIN

date there is no evidence supporting or opposing this hypothesis in humans. Here, we demonstrate that KCC2 expression is decreased in superficial dorsal horn neurons of organ donors who died with a do...

journals.lww.com

1 8 36

Reposted by Simon Beggs

Tiziana Metitieri @timetit.bsky.social · Jul 15

Happy birthday Brenda Milner! 🧠🎉
Today is her 107th birthday, she's a legend, a superhero.

Nicole Rust @nicolecrust.bsky.social · May 13

My favorite account of the early history is this one:

www.jneurosci.org/content/jneu...

ALSO: AWARD BRENDA MILNER THE NOBEL PRIZE (for work with H.M. and the discovery that the hippocampus the structure that stores memories) - SHE'S 106!)
www.amightygirl.com/blog?p=25635

Heroes of the Engram
In 1904, Richard Semon introduced the term “engram” to describe the neural substrate responsible for (or at least important in) storing and recalling memories (i.e., a memory trace). The recent introduction of a vast array of powerful new tools to probe and manipulate memory function at the cell and neuronal circuit level has spurred an explosion of interest in studying the engram. However, the present “engram renaissance” was not borne in isolation but rather builds on a long tradition of memory research. We believe it is important to acknowledge the debts our current generation of scientists owes to those scientists who have offered key ideas, persevered through failed experiments and made important discoveries before us. Examining the past can also offer a fresh perspective on the present state and future promise of the field. Given the large amount of empirical advances made in recent years, it seems particularly timely to look back and review the scientists who introduced the seminal terminology, concepts, methodological approaches, and initial data pertaining to engrams. Rather than simply list their many accomplishments, here we color in some details of the lives and milestone contributions of our seven personal heroes of the engram (Richard Semon, Karl Lashley, Donald Hebb, Wilder Penfield, Brenda Milner, James McConnell, and Richard Thompson). In reviewing their historic role, we also illustrate how their work remains relevant to today’s studies.

2 14 50

Simon Beggs @simonbeggslab.bsky.social · Jun 27

“It wasn’t like a man, it was like some damned juggernaut”

1

Simon Beggs @simonbeggslab.bsky.social · Jun 5

This is *exactly* what today needed. I am, as ever, in your debt. Cheers!

1 1

Simon Beggs @simonbeggslab.bsky.social · May 15

Very sorry to read this, Stephani. Wishing you all the best for whatever’s next.

2

Simon Beggs @simonbeggslab.bsky.social · May 14

How about using Ancho Reyes instead of vodka? Why am I asking? Will report back!

1 1

Simon Beggs @simonbeggslab.bsky.social · May 13

This is fantastic! The lime really elevates it, can't imagine going back to an El Presidente after this, although I should probably make one now, just to be sure...

1 1

Reposted by Simon Beggs

Ted Price @tedpricethepainguy.bsky.social · May 11

And the office of Pain Policy and Planning was eliminated. That office has coordinated pain research across NIH for ages and played a key role in many important initiatives.

5 9

Simon Beggs @simonbeggslab.bsky.social · May 6

1

Simon Beggs @simonbeggslab.bsky.social · Apr 29

Elbows out and Bottoms Up! Cheers!

1

Simon Beggs @simonbeggslab.bsky.social · Apr 27

Sometimes the answer is an absinthe fountain. Saturday night at The Parlour with @skochlab.bsky.social working out what the question is.

1 5

Simon Beggs @simonbeggslab.bsky.social · Apr 22

Yes it’s three penguin kites on a beach in Le Touquet, what of it?

1 2

Simon Beggs @simonbeggslab.bsky.social · Apr 15

The world is your oyster, quite literally here in Le Touquet in Normandy. I do enjoy a challenge…

1

Simon Beggs @simonbeggslab.bsky.social · Apr 13

A much needed escape to the bucolic Kent countryside for some vintage motorcycle racing. The roar of ancient machines and the perfume of Castrol R in the air. Delicious!

7

Reposted by Simon Beggs

Tom Wallach @mdwallach.bsky.social · Apr 10

Just thinking about how much time I spend applying for grants and how this dumb shit is gonna spend 20 million or something on this dumb nonsense and will publish it in cureus next to Vinay Prasads latest paper “why Arnold ventures should be allowed to buy people and execute them for sport”

Aaron Rupar @atrupar.com · Apr 10

RFK Jr: "By September we will know what has caused the autism epidemic and we will be able to eliminate those exposures."

5 7 28

Simon Beggs @simonbeggslab.bsky.social · Apr 7

Congratulations Greg!

1 1

Reposted by Simon Beggs

⚡️GREG_CORDER⚡️ @flybottleescape.bsky.social · Apr 5

🧠🐭📊🔬🧬BIG PREPRINT UPDATES:

Mimicking opioid analgesia in cortical pain circuits

We built a brain-behavior framework to decode spontaneous chronic pain in mice—and to biologically mimic morphine with our synthetic opioid gene therapy

www.biorxiv.org/content/10.1...

1/15

5 6 21