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Steve Turner @sjturn.bsky.social · 2h

Day 2 of the @embo.org @events.embl.org #EESImaging symposia. Exciting day of science ahead focussing on dynamic single molecule imaging, can’t wait to apply some of this to our own work #scienceyeah #Tcellsarecool #smlmisverycool

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Steve Turner @sjturn.bsky.social · 22h

Oops, I meant #EESImaging

Steve Turner @sjturn.bsky.social · 22h

Excited to be at the @events.embl.org #EEEImaging conference in Heidelberg, Germany, hearing the latest in cutting edge imaging of biological systems. The ATC (G) building is modelled on the double DNA helix, the bridges represent the H bonds b/n nucleotides #scienceyeah #microscopyiscool

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Reposted by Steve Turner

Nicole Robb @nicolerobb.bsky.social · 19d

Excited to announce our latest preprint, exploring the stereochemistry & antiviral properties of natural product MM46115 (pellemicin) against influenza. 🦠 💊 Big thanks to all co authors, including @afifahtasnim.bsky.social @craigpthomp.bsky.social and others. www.biorxiv.org/content/10.1...

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Steve Turner @sjturn.bsky.social · 7d

Bit of colour @monashuniversity.bsky.social today #springshower #melbourneweather #capturemonash

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Steve Turner @sjturn.bsky.social · 8d

In the #BDI infection program retreat, listening to Fran Short, Dept of Micro @monashuniversity.bsky.social Sampling of fresh creek water identified pathogenic E. coli in microbial communities, highly active AMR gene and virulence determinants #dontswiminthedandenongcreek

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Steve Turner @sjturn.bsky.social · 8d

Who remembers these note books? Once a common sight in labs for recording keeping. Was cleaning out my office for a move into a new role and found a set of books from a past grad student, love the fact there is raw data, protocols, even mouse cards all in one place #scienceyeah

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Steve Turner @sjturn.bsky.social · 8d

Quince tree update: we have blooming 💐 now just need bees to pollinate

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Steve Turner @sjturn.bsky.social · 16d

@leonsmyth.bsky.social just gave a fascinating talk on how brain substructures enable brain waste management, interface with immune cells @monashuniversity.bsky.social

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Steve Turner @sjturn.bsky.social · 17d

Quince tree update: We have flower buds, I repeat, we have flower buds

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Steve Turner @sjturn.bsky.social · 20d

TFW the new protocol your grad student set up to test a harebrained idea looks like it worked! #superstargradstudent #Tcellsarecool #epigeneticsiscool #scienceyeah @pacbio.bsky.social #pacbioapplications

Steve Turner @sjturn.bsky.social · Sep 7

Spring is coming #blossoms #springhassprung #quincetreeflowerimg

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Steve Turner @sjturn.bsky.social · Sep 4

Just read the draft of Australia’s National Health & Medical Research Strategy. Great to see full funding of research being addressed as a need — but an emphasis on discovery research is missing. You can’t drive impact without fueling the pipeline with fundamental/discovery science.

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Steve Turner @sjturn.bsky.social · Aug 27

Up next, talking with 2nd yr microbiology students @monashuniversity.bsky.social about how the innate immune system engages with different pathogens, RNA viruses 🦠 Gram +ves, DNA viruses, Gram -ves #scienceyeah #microbiologyiscool #campuslife

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Steve Turner @sjturn.bsky.social · Aug 21

Currently sitting in a seminar from Chris Stubenrauch, learning how efflux pumps found in Gram -ve bugs are also found in Gram +ve bugs, instead of outer membrane interactions, they interact with outer protein layers instead @monashuniversity.bsky.social #scienceyeah #microbesarecool

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Steve Turner @sjturn.bsky.social · Aug 18

So worth it!

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Steve Turner @sjturn.bsky.social · Aug 18

Melbourne is a pretty city at night

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Steve Turner @sjturn.bsky.social · Aug 7

Just finished up an amazing visit to Harry Perkins Medical Institute in Perth. It was a reminder of why I love research. Getting to present our most recent findings, getting great questions, learning about the cool science others are doing, and coming away with new collaborations #scienceyeah

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Steve Turner @sjturn.bsky.social · Jul 31

New preprint: Ever wonder why memory T cells can look like naive T cells but act like effectors? Part the reason is that a chromatin binding protein called SATB1 restrains acquisition of effector phenotypes. Shout out to my grad student Jason Kah for this work. www.biorxiv.org/cgi/content/...

SATB1 maintains naive-like identity in antiviral CD8⁺ T cells by limiting chromatin remodelling at effector gene loci.

Optimal CD8+ T cell differentiation requires the engagement of transcriptional programs that drive effector phenotypes and function, whilst also shutting down transcriptional programs that maintain th...

www.biorxiv.org

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Steve Turner @sjturn.bsky.social · Jul 26

This is a wonderful study, it is amazing to watch how immune cells can get into tight spaces…

Waggoner Lab @labwaggoner.bsky.social · Jul 25

T cells must preserve their structural integrity while migrating through dense environments. A central actin pool under confinement balances forward propulsion with shape integrity to protect nucleus from DNA damage @sciimmunology.bsky.social
www.science.org/doi/10.1126/...

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Steve Turner @sjturn.bsky.social · Jul 23

This is a wonderful paper. Addressing the age old question: how do chromatin remodellers know where to go? I am sharing this with my grad students and postdocs, and what the hell, anyone else that is interested #epigeneticsiscool #transcriptioniscool #scienceyeah

H. Courtney Hodges @hodgeshc.bsky.social · Jul 22

How do chromatin remodelers use #IDRs to find TF binding partners? In our new Molecular Cell paper, we show that β-catenin is an adaptor that links SWI/SNF (cBAF) subunit ARID1A with binding partners via IDR-domain interactions.
www.cell.com/molecular-ce...

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Steve Turner @sjturn.bsky.social · Jul 23

A smorgasbord of immunity seminars this week. Today, we are excited to hear from Prof Kate Schroder, and her uncomfortable truth that the adaptive immune system is important, how inflammasomes can promote effective adaptive immune responses #immunityiscool #inflammasomesarereallycool #scienceyeah

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Steve Turner @sjturn.bsky.social · Jul 22

Prof David Tarlinton telling us about the dynamics of long lived plasma cells. Turns out B cells are also cool, #plasmacellsareforever #immunologyiscool #scienceyeah @monashuniversity.bsky.social

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Steve Turner @sjturn.bsky.social · Jul 21

Networking with biomedical research stars of the future, introducing immunology to the 1st and 2nd yr Biomedical scholars #immunologyiscool #scienceyeah

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Steve Turner @sjturn.bsky.social · Jul 14

A quiet day meeting wise, allowing me to do some reading and prep to write a new review about Killer T cells, now gotta stop procrastinating and get back to it #academicsky #labheadlife #Tcellsarecool #immunityiscool #scienceyeah

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