Jase Gehring
@skyjase.bsky.social
490 followers 1.1K following 860 posts
scientist at UC Berkeley inventing advanced genomic technologies lover of molecules, user of computers https://scholar.google.com/citations?user=63ZRebIAAAAJ&hl=en
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skyjase.bsky.social
web developers using a stochastic generative algorithm:

omg it's alive u guys. it has rights
skyjase.bsky.social
beating a dead horse, but it is just the height of hubris and ignorance to think that the only thing standing in the way of chemical and bioterrorism is access to a chatbot
skyjase.bsky.social
yup. and even worse intuition for software! not only is software the foundation of modern weapons, propaganda, terrorist and state attacks, etc... LLMs are way, way more powerful for software applications than science!

their threat model is completely backwards
skyjase.bsky.social
OpenAI launched a deepfake propaganda video generator the very same day they deactivated my account for asking basic questions about laboratory research.

LLM companies aren't serious about safety OR advancing scientific research.
skyjase.bsky.social
LLMs have been bricked for biomedical research. OpenAI deactivated my account ('weapons'). Claude won't engage

question: in the last decade, how many hospitals have been held for ransom with chemical, biological, or radiological weapons? and how many have been held for ransom by cyberattacks?
skyjase.bsky.social
it's weird that the web browser has taken over desktop but phones have been colonized by apps. are apps better for thumb-based GUIs? or gathering more user telemetry? or maybe the desktop is just a portal for search and cloud access?
skyjase.bsky.social
oh with some cute text formatting!! they coulda gone for the full plasmid-design-in-a-Word-doc annotations but i guess this is a bit more tasteful, restrained
skyjase.bsky.social
between global researchers choosing the EU over the US, Europeans doing the same, and Americans making the jump.. the EU is going to be flooded with researchers. it's a historical opportunity and Europe would do well to take full advantage
lastpositivist.bsky.social
This is probably a desired goal for the Trump regime? They have inconsistent preferences mind you so there's another sense in which this is undesired. But "drive out the intelligentsia and weaken academia" is, under this aspect, a favoured policy goal of theirs.

www.politico.eu/article/euro...
Top US researchers rush to relocate to Europe
U.S.-based applicants to a prestigious EU research scheme have increased five-fold.
www.politico.eu
skyjase.bsky.social
Haven’t seen that so far! I’m doing some side by sides on generated designs versus colabfold and esmfold, but not done yet. Would be curious how the same sequences fold using other models
Reposted by Jase Gehring
cryoempapers.bsky.social
Cryo-electron tomography reconstructs polymer in liquid film for fab-compatible lithography pubmed.ncbi.nlm.nih.gov/41027883/ #cryoem
skyjase.bsky.social
Congrats Ben! Great work
skyjase.bsky.social
the Gemini button on Chrome browser. you tell it to go away it becomes a slightly smaller button

worst demand vs capital investment of any technology in history
crushbort.bsky.social
oh hell yeah pop ups on my work computer telling me to try copilot or click “later” that then disappear before i can click the settings. definitely don’t kill the guy who put that in
skyjase.bsky.social
mesmerizing wagon-wheel effect using hi-speed camera and droplet generator. droplets enter the channel from the top, flowing counterclockwise around the bend, a mixing feature. droplet generation rate is ~1kHz, droplet size ~80 microns
skyjase.bsky.social
That server was so great. i inferred thousands of structures
skyjase.bsky.social
email is awful. whether you prefer email depends on if the work you are doing is better or worse than awful.
orzelc.bsky.social
I'm more interested in "refuse to go to a meeting when it could be an email" vs "refuse to read an email when they could call a meeting"
kattenbarge.bsky.social
The real generational divide is people who refuse to watch a video if it could be an article versus people who refuse to read an article if it could be a video
skyjase.bsky.social
sac is clustering cells by phenotype, the spatial part being the phenotypes and maybe relative positions of neighboring cells. Segmentation is drawing outlines around cells or other structures in an image. It’s a primitive in image analysis, often used to define cells for sac
skyjase.bsky.social
it appears this may have to do with chatbot companies declaring themselves ASL-3 (lmao). this would be rather embarrassing for them, except they are using these "safety measures" as a fig leaf to avoid real regulation. joke's on us.

support.claude.com/en/articles/...
Understanding Sonnet 4.5's Safety Filters | Anthropic Help Center
support.claude.com
skyjase.bsky.social
claude was responsive until today when it has now become TOO POWERFUL to answer queries regarding laboratory chemistry. again, no weapons nothing even remotely close to weapons.
a man is screaming with the words " unlimited power " behind him
ALT: a man is screaming with the words " unlimited power " behind him
media.tenor.com
skyjase.bsky.social
i have had similar in-person conversations with OpenAI employees, minus the insults.
skyjase.bsky.social
i did have conversations with ChatGPT about its restrictions around biomedical research. i also said some insulting things to ChatGPT about ChatGPT and OpenAI and its employees. because their policies are inane. self-serving. uninformed.