Sonja Hofer
@sonjahofer.bsky.social
720 followers 120 following 13 posts
Neuroscientist studying neural circuits underlying perception and behaviour. Professor at the Sainsbury's Wellcome Centre, London
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sonjahofer.bsky.social
Should you stick to your goal, try something else, or give up? Your median raphe nucleus in the brainstem knows and will decide for you 😉. First foray of my lab into foraging, behavioural strategies and exploration. Amazing work from the one and only Mehran Ahmadlou: www.nature.com/articles/s41...
A subcortical switchboard for perseverative, exploratory and disengaged states - Nature
Behavioural experiments in mice demonstrate that GABAergic (γ-aminobutyric acid-expressing), glutamatergic and serotonergic neurons in the median raphe nucleus have distinct and complementary function...
www.nature.com
sonjahofer.bsky.social
Thanks so much everyone!
sonjahofer.bsky.social
Mehran collected mindboggling amounts of data and used many behavioural paradigms to get a holistic understanding of the function of median raphe cell types. Mehran will start his own lab in Oxford soon, watch out for this absolute neuroscience star!
sonjahofer.bsky.social
Should you stick to your goal, try something else, or give up? Your median raphe nucleus in the brainstem knows and will decide for you 😉. First foray of my lab into foraging, behavioural strategies and exploration. Amazing work from the one and only Mehran Ahmadlou: www.nature.com/articles/s41...
A subcortical switchboard for perseverative, exploratory and disengaged states - Nature
Behavioural experiments in mice demonstrate that GABAergic (γ-aminobutyric acid-expressing), glutamatergic and serotonergic neurons in the median raphe nucleus have distinct and complementary function...
www.nature.com
sonjahofer.bsky.social
Hi Michael, sorry for the delay, the article is now available to download on my labs webwite: www.sainsburywellcome.org/web/groups/h...
Hofer Lab | Sainsbury Wellcome Centre
www.sainsburywellcome.org
sonjahofer.bsky.social
Thanks so much, Tim!! 😊
sonjahofer.bsky.social
So excited to see this out, heroic effort by the brilliant Sara Mederos, uncovering the detailed brain mechanisms of how animals learn to overcome their instinctive fear responses, from neural circuits & cell types down to synaptic plasticity mechanism! www.science.org/doi/10.1126/...
Overwriting an instinct: Visual cortex instructs learning to suppress fear responses
Fast instinctive responses to environmental stimuli can be crucial for survival but are not always optimal. Animals can adapt their behavior and suppress instinctive reactions, but the neural pathways...
www.science.org
Reposted by Sonja Hofer
carandinilab.net
Neuropixels and Optogenetics are delighted to announce the birth of

Neuropixels Opto

Combining high-resolution electrophysiology and optogenetics

Today in bioRxiv

960 sites, 28 emitters, 2 colors

By Lakunina, @karolinazsocha.bsky.social, Ladd, et al

www.biorxiv.org/content/10.1...

(1/2)
A Neuropixels Opto probe with 3 blue emitters and 3 red emitters lighting up in succession, with corresponding neural activity in different layers of the cortex.
sonjahofer.bsky.social
Hi Guido, could you please add me? Thanks!!
sonjahofer.bsky.social
Could you please add me too? Thanks a lot!!
sonjahofer.bsky.social
Hi Mark, thanks for the list, could you also add me? Thanks!!
sonjahofer.bsky.social
Hi Christos, could you please add me too? Thanks a lot!!
sonjahofer.bsky.social
Recurrent inter-areal connections implement line-attractors that promote consensus-building and consistency in visual representations across cortical areas.
sonjahofer.bsky.social
Cool study led by Mitra Javadzadeh and
Marine Schimel on the function of inter-areal communication in the neocortex, using data from my lab and biologically-constrained latent circuit modelling with Guillaume Hennequin and Yasha Ahmadian #neurosky #neuroskyence www.biorxiv.org/content/10.1...
Dynamic consensus-building between neocortical areas via long-range connections
The neocortex is organized into functionally specialized areas. While the functions and underlying neural circuitry of individual neocortical areas are well studied, it is unclear how these regions op...
www.biorxiv.org
sonjahofer.bsky.social
Hi, I'm new to Bluesky fleeing from X. How can I find the neuroscience crowd?