Spencer LaVere Smith
@spencerlaveresmith.bsky.social
270 followers 410 following 76 posts
Prof. @ucsantabarbara.bsky.social ‪- Runs a lab slslab.org - Works on computation, neuroscience, behavior, vision, optics, imaging, 2p / multiphoton, optical computing, machine learning / AI - Blogs at labrigger.com - Founded @pacificoptica.bsky.social
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spencerlaveresmith.bsky.social
Still a few weeks left!
mariusschneider.bsky.social
🚨Our NeurIPS 2025 competition Mouse vs. AI is LIVE!

We combine a visual navigation task + large-scale mouse neural data to test what makes visual RL agents robust and brain-like.

Top teams: featured at NeurIPS + co-author our summary paper. Join the challenge!

Whitepaper: arxiv.org/abs/2509.14446
Mouse vs. AI: A Neuroethological Benchmark for Visual Robustness and Neural Alignment
Visual robustness under real-world conditions remains a critical bottleneck for modern reinforcement learning agents. In contrast, biological systems such as mice show remarkable resilience to environ...
arxiv.org
Reposted by Spencer LaVere Smith
ucsantabarbara.bsky.social
Exciting news: #UCSB physicists John Martinis and Michel Devoret have been awarded the 2025 #NobelPrize in Physics. They were lauded for work that, according to the Royal Swedish Academy of Sciences, "revealed quantum physics in action."

Full story: https://ow.ly/TH7K50X7ULp
UCSB physics professors John Martinis and Michel Devoret win 2025 Nobel Prize in Physics
UCSB physics professors John Martinis and Michel Devoret win 2025 Nobel Prize in Physics
ow.ly
Reposted by Spencer LaVere Smith
metaomicsnerd.bsky.social
We got some more Gaucho Nobels! #UCSB
UC Santa Barbara celebrates new Nobel Prize winners! UCSB professors John Martinis and Michel Devoret have been awarded the 2025 Nobel Prize in Physics
spencerlaveresmith.bsky.social
Thanks for sharing this.

Another bit of his writing: www.abrahamlincolnonline.org/lincoln/spee...

Sharing a country....
Lincoln articulated it well.
"I look upon that enactment not as a law, but as violence from the beginning."
" [...] I do not doubt their candor. But they never vote that way."
Abraham Lincoln's 1855 Letter to Joshua Speed
www.abrahamlincolnonline.org
Reposted by Spencer LaVere Smith
annadevor.bsky.social
Chris Xu talks to Neurophotonics about the 'toy land of optics' and how to channel positive vibes! Thank you Tianyu Wang for conducting this fantastic interview!
www.spiedigitallibrary.org/journals/neu...
#Neurophotonics #Neuroscience #Neuroimaging #BrainImaging #OpticalImaging #Microscopy
Reposted by Spencer LaVere Smith
mbeyeler.bsky.social
👁️🧠 New preprint: We demonstrate the first data-driven neural control framework for a visual cortical implant in a blind human!

TL;DR Deep learning lets us synthesize efficient stimulation patterns that reliably evoke percepts, outperforming conventional calibration.

www.biorxiv.org/content/10.1...
Diagram showing three ways to control brain activity with a visual prosthesis. The goal is to match a desired pattern of brain responses. One method uses a simple one-to-one mapping, another uses an inverse neural network, and a third uses gradient optimization. Each method produces a stimulation pattern, which is tested in both computer simulations and in the brain of a blind participant with an implant. The figure shows that the neural network and gradient methods reproduce the target brain activity more accurately than the simple mapping.
Reposted by Spencer LaVere Smith
superkash.bsky.social
8th grade trip to DC chaperoning is done. Kids were great. Lots of highlights for me... But I really enjoyed seeing the FDR memorial.
A photo taken at the FDR memorial which says we must scrupulously guard the civil Rights and civil liberties of all citizens whatever their background we must remember that any oppression or injustice any hatred is a wedge designed to attack our civilization.
Reposted by Spencer LaVere Smith
ritastrack.bsky.social
Now 3/4 of the way through the @picoquant.bsky.social single-molecule meeting, and I want to share some takeaways and observations (in no particular order of importance)! If you're here, please feel free to add to this thread!
Reposted by Spencer LaVere Smith
dlevenstein.bsky.social
Bet: this flavor of same-stimulus, same-task, compare-behavior, compare-physiology is the future of model testing and theory development in neuroscience.
mariusschneider.bsky.social
🚨Our NeurIPS 2025 competition Mouse vs. AI is LIVE!

We combine a visual navigation task + large-scale mouse neural data to test what makes visual RL agents robust and brain-like.

Top teams: featured at NeurIPS + co-author our summary paper. Join the challenge!

Whitepaper: arxiv.org/abs/2509.14446
Mouse vs. AI: A Neuroethological Benchmark for Visual Robustness and Neural Alignment
Visual robustness under real-world conditions remains a critical bottleneck for modern reinforcement learning agents. In contrast, biological systems such as mice show remarkable resilience to environ...
arxiv.org
Reposted by Spencer LaVere Smith
mariusschneider.bsky.social
🚨Our NeurIPS 2025 competition Mouse vs. AI is LIVE!

We combine a visual navigation task + large-scale mouse neural data to test what makes visual RL agents robust and brain-like.

Top teams: featured at NeurIPS + co-author our summary paper. Join the challenge!

Whitepaper: arxiv.org/abs/2509.14446
Mouse vs. AI: A Neuroethological Benchmark for Visual Robustness and Neural Alignment
Visual robustness under real-world conditions remains a critical bottleneck for modern reinforcement learning agents. In contrast, biological systems such as mice show remarkable resilience to environ...
arxiv.org
spencerlaveresmith.bsky.social
Innovative. This is China? The t-shirt says “izakaya”, right? This establishment seems like an interesting blend of cultures.
Reposted by Spencer LaVere Smith
ucsantabarbara.bsky.social
Tell me you go to #UCSB without telling me.
Blue on residential housing that says “Wash sand off of your feet before you enter.” Bikes parked by residential housing at UCSB. Surfboard racks outside of residential housing at UCSB
spencerlaveresmith.bsky.social
Now available: updated Google Maps from the areas of the Palisades and Eaton fires (01/2025). Over 16,000 homes and other structures destroyed. #2 and #3 most in CA history (since at least the 1940s). en.wikipedia.org/wiki/Palisad... en.wikipedia.org/wiki/Eaton_F... (before/after images)
spencerlaveresmith.bsky.social
I published a paper in Nature Methods. They invoiced us for $10,690.00. It was extra expensive because I wanted it to be open access. US taxpayers fund it, and they also funded the research.

It's nice to have other outlets like NBDT, which is free. nbdt.scholasticahq.com/for-authors
spencerlaveresmith.bsky.social
The info has been out there, and it was phased in this year.

There are some concerns, and we'll have to see how things shake out.
drugmonkey.wordpress.com/2025/08/27/t...

Regardless, I appreciate the work that good people put into this. I'm optimistic that it is an improvement.
(3/3)
spencerlaveresmith.bsky.social
So many good lines in the guidance materials too.

Looking forward to this next study section.

I assume Noni Byrnes and Mike Lauer were key in this effort. The NIH lost them both this year. I hope they are doing well. I appreciate all of the current NIH employees keeping the ship running!
(2/3)
spencerlaveresmith.bsky.social
The people at the NIH did an excellent job with the Simplified Review Framework.

1. Should it be done?
Sets the limit for the overall score.

2. Can it be done well?
Assess rigor & feasibility

3. Sufficient expertise and resources?
Either "sufficient" or list weaknesses.

That's it.
(1/3)
spencerlaveresmith.bsky.social
Interesting idea. Could be good if done well. As a supplement, not a replacement, for NIH, NSF, etc.

CA state tax revenue shouldn’t have to replace Fed R&D $. CA researchers should have a fair shot at competing for federal funds that CA taxpayers pay into. Gift link www.nytimes.com/2025/09/13/u...
California’s $23 Billion Plan to Restore Federal Cuts to Scientific Research
www.nytimes.com
Reposted by Spencer LaVere Smith
ucsantabarbara.bsky.social
#UCSB has secured a lease on a 105k-square-foot R&D facility in Goleta 🔬🌊

Aptly named OASIS, the facility will be a launchpad for cutting-edge technologies, helping power UCSB’s impact on innovation and U.S. economic growth.

Full story: ow.ly/ACZX50WTimn
Goleta R&D hub positions UCSB as national model for tech transfer
A launchpad for cutting-edge technologies, the new facility helps power UCSB’s impact on innovation and U.S. economic growth
ow.ly
spencerlaveresmith.bsky.social
After your SfN in San Diego, drift 130 km up the coast to Irvine for a bit more: cncm.medschool.uci.edu/2025-special... Go ahead and register now.