stephorch.bsky.social
Stephanie Orchanian
@stephorch.bsky.social
22 followers 46 following 2 posts
UCLA Chancellor’s Postdoctoral Fellow studying the maternal gut microbiome
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stephorch.bsky.social
Stephanie Orchanian @stephorch.bsky.social · Jul 10
Excited to share our recent publication in this month's issue of mBio, based on my PhD research. We show that replication of 𝘛. 𝘨𝘰𝘯𝘥𝘪𝘪 is required to trigger a localized immune response in the brain! 🧠 bit.ly/3TA9ALj
Toxoplasma gondii parasites induce a localized myeloid cell immune response surrounding parasites in the brain during acute infection | mBio
Toxoplasma gondii is a brain-infecting parasite, and the mobilization of peripheral immune cells to the brain is critical for controlling T. gondii infection. However, the initial events driving these...
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Reposted by Stephanie Orchanian
pipethero.bsky.social
Elaine Hsiao @pipethero.bsky.social · May 2
Thrilled to share this collaborative work by Kristie Yu, Francis Chandra, Amina Schartup and teams @Scripps_Ocean and @UCLA showing that an engineered gut bacterium can be used to reduce the neurotoxic effects of dietary methylmercury www.cell.com/cell-host-mi...
An engineered gut bacterium protects against dietary methylmercury exposure in pregnant mice
Yu and Chandra et al. engineered a commensal gut microbe, Bacteroides thetaiotaomicron, to detoxify methylmercury (MeHg). The engineered bacterium reduces MeHg in the intestinal lumen, limits its accu...
www.cell.com
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Reposted by Stephanie Orchanian
jci.org
Journal of Clinical Investigation @jci.org · Feb 20
Maternal microbiome is a cornerstone of maternal and fetal health. https://buff.ly/431YoNu

@stephorch.bsky.social‬ & @pipethero.bsky.social highlight gut microbiome x environmental interactions at the maternal-fetal interface that influence the brains of pregnant people and developing offspring.
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stephorch.bsky.social
Stephanie Orchanian @stephorch.bsky.social · Feb 17
Curious about how the gut microbiome modulates the neurological health of pregnant women and their offspring? Check out my recent review with @pipethero.bsky.social out now @jclinical-invest.bsky.social! 🦠🤰👶🧠

www.jci.org/articles/vie...
JCI - The microbiome as a modulator of neurological health across the maternal-offspring interface
www.jci.org
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